DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14710 and Neu2

DIOPT Version :9

Sequence 1:	NP_650092.4	Gene:	CG14710 / 41393	FlyBaseID:	FBgn0037920	Length:	415	Species:	Drosophila melanogaster
Sequence 2:	NP_649316.1	Gene:	Neu2 / 40375	FlyBaseID:	FBgn0037085	Length:	382	Species:	Drosophila melanogaster

Alignment Length:	178	Identity:	56/178 - (31%)
Similarity:	86/178 - (48%)	Gaps:	20/178 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   243 KDINAKER-----------GNQP-------KCKEEEKFMCILCGNVFYKKSVFTAHMMTHSEYKP 289
            :::.|.||           ||:|       |.||:..|.|..|...|..||....||.:|:..:|
  Fly    82 EEVEAAERDLQDGADDVDSGNEPDINECDIKAKEKPGFSCSHCPKSFQVKSNLKVHMRSHTGERP 146

  Fly   290 HQCEICNKSFRQMGELRAHIRRHTGDRPYKCMYCDRHFYDRSERVRHERVHTNTRPYACQECGKT 354
            ..|.:|.|||.....|:.|:|.|||:||::|.:|.|.|........|.::|.......|..|.|.
  Fly   147 FTCSLCPKSFGYSSGLQNHMRTHTGERPFQCSHCPRSFTAGHHLKAHIQMHERRGSLRCPYCQKC 211

  Fly   355 FTHTAILKNHILSHSAQKNYNCGICCKSFTLLHQLKAHLQTLTHRNKM 402
            |..:.|||.|:.:|:.:..:.|..|.|||.:.|:|..|::  .|:.::
  Fly   212 FLTSLILKQHLATHTDETQFKCSQCSKSFQVEHELWMHMR--VHQERL 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14710	NP_650092.4	zf-AD	9..83	CDD:285071
		COG5048	<261..395	CDD:227381	46/133 (35%)
		C2H2 Zn finger	264..284	CDD:275368	7/19 (37%)
		zf-C2H2	290..312	CDD:278523	8/21 (38%)
		C2H2 Zn finger	292..312	CDD:275368	8/19 (42%)
		zf-H2C2_2	304..327	CDD:290200	11/22 (50%)
		C2H2 Zn finger	320..340	CDD:275368	5/19 (26%)
		zf-H2C2_2	335..357	CDD:290200	6/21 (29%)
		C2H2 Zn finger	348..368	CDD:275368	8/19 (42%)
		C2H2 Zn finger	376..395	CDD:275368	8/18 (44%)
Neu2	NP_649316.1	zf-AD	1..63	CDD:285071
		COG5048	<119..241	CDD:227381	42/121 (35%)
		C2H2 Zn finger	121..141	CDD:275368	7/19 (37%)
		zf-H2C2_2	133..158	CDD:290200	9/24 (38%)
		C2H2 Zn finger	149..169	CDD:275368	8/19 (42%)
		zf-H2C2_2	162..185	CDD:290200	11/22 (50%)
		C2H2 Zn finger	177..197	CDD:275368	5/19 (26%)
		C2H2 Zn finger	205..225	CDD:275368	8/19 (42%)
		zf-C2H2_8	206..286	CDD:292531	17/54 (31%)
		C2H2 Zn finger	233..253	CDD:275368	8/21 (38%)
		C2H2 Zn finger	260..297	CDD:275368
		C2H2 Zn finger	303..323	CDD:275368
		C2H2 Zn finger	353..373	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446595
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930