DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14710 and CG17385

DIOPT Version :9

Sequence 1:	NP_650092.4	Gene:	CG14710 / 41393	FlyBaseID:	FBgn0037920	Length:	415	Species:	Drosophila melanogaster
Sequence 2:	NP_001286418.1	Gene:	CG17385 / 36603	FlyBaseID:	FBgn0033934	Length:	278	Species:	Drosophila melanogaster

Alignment Length:	194	Identity:	65/194 - (33%)
Similarity:	96/194 - (49%)	Gaps:	16/194 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   232 RKPDAELKFKR-KDINAKERGNQPKCKEEEKFMCILCGNVFYKKSVFTAHMMTHSEYKPHQCEIC 295
            ::.|...:.|| :.::.:|..|..|...|    |.||...|........||..|::.:|..|.||
  Fly    19 KRCDRTFRSKRDQTLHRQEVHNHNKTTYE----CKLCAKSFCNSGNLDRHMKVHNDVRPFVCNIC 79

  Fly   296 NKSFRQMGELRAHIRRHTGDRPYKCMYCDRHFYDRSERVRHERVHTNTRPYACQECGKTFTHTAI 360
            :|:|.|...|:.|...|:|:||:.|.:|::.|..:|...||:..||..:|:.||.||:.|:....
  Fly    80 SKAFAQAVNLQRHYAVHSGERPFTCNFCNKSFTQQSNMKRHKMTHTGEKPFRCQRCGRYFSQLVN 144

  Fly   361 LKNHILSHSAQKNYNCGICCKSFTLLHQLKAHLQTLTH-RNKMEQTIPSS--------PEMLES 415
            ||.|.|.|...|.|.|..|.|.||.|...|.|||  :| :..::..:|:|        .|.|||
  Fly   145 LKKHKLGHLNAKPYQCNYCEKGFTQLSNFKRHLQ--SHIKEGVDVDVPASIQAAAALARERLES 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14710	NP_650092.4	zf-AD	9..83	CDD:285071
		COG5048	<261..395	CDD:227381	50/133 (38%)
		C2H2 Zn finger	264..284	CDD:275368	6/19 (32%)
		zf-C2H2	290..312	CDD:278523	8/21 (38%)
		C2H2 Zn finger	292..312	CDD:275368	8/19 (42%)
		zf-H2C2_2	304..327	CDD:290200	8/22 (36%)
		C2H2 Zn finger	320..340	CDD:275368	6/19 (32%)
		zf-H2C2_2	335..357	CDD:290200	10/21 (48%)
		C2H2 Zn finger	348..368	CDD:275368	9/19 (47%)
		C2H2 Zn finger	376..395	CDD:275368	9/18 (50%)
CG17385	NP_001286418.1	COG5048	<13..181	CDD:227381	58/167 (35%)
		C2H2 Zn finger	18..39	CDD:275368	4/19 (21%)
		C2H2 Zn finger	48..68	CDD:275368	6/19 (32%)
		C2H2 Zn finger	76..96	CDD:275368	8/19 (42%)
		C2H2 Zn finger	104..124	CDD:275368	6/19 (32%)
		C2H2 Zn finger	132..148	CDD:275368	7/15 (47%)
		C2H2 Zn finger	160..180	CDD:275368	10/21 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446661
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930