DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14710 and CG15436

DIOPT Version :9

Sequence 1:	NP_650092.4	Gene:	CG14710 / 41393	FlyBaseID:	FBgn0037920	Length:	415	Species:	Drosophila melanogaster
Sequence 2:	NP_608840.1	Gene:	CG15436 / 33657	FlyBaseID:	FBgn0031610	Length:	346	Species:	Drosophila melanogaster

Alignment Length:	391	Identity:	90/391 - (23%)
Similarity:	139/391 - (35%)	Gaps:	119/391 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 CRICLGDFEESQMICLFGDKGESDLRKKLEL--------CCRIRVRQSPQLPEKACNSCCEFVQM 66
            ||:|: |. ..:::.:|      |.|::..:        |....|::.....|..|..|.|.|:.
  Fly     5 CRVCM-DI-SGKLVNIF------DARRRTRVSIAEMIAQCTGFEVKRGDLFSEMICPQCYEDVKS 61

  Fly    67 WFNFRQMCLNSQVYWETSSSERPEALAQASDAEYMLYLYENLHLKLGTENQEKEEITAIEEGDEQ 131
            .:..||.|..|..:                            :.::..|..|......:||.|.:
  Fly    62 AYGIRQTCEESHQF----------------------------YCRVRDEGIEDALCALLEEEDWE 98

  Fly   132 QEDQSQEVLDFNGFIINESIEEDEEPNTESPEQILISHMDSYVDDQQMEELIDDKGELVEELSNA 196
                               |.|||:...:|                  ....||.|
  Fly    99 -------------------ISEDEDARIDS------------------ASAADDDG--------- 117

  Fly   197 NTFYEVEYGDEELLMSSAPSPHPSFKMDKQKPGRPRKPDAELKFKRKDINAKERGNQPKCKEEEK 261
                                     |.|.:|.....: :...|::||....:.....   .:.:.
  Fly   118 -------------------------KSDSKKVAFECR-ECHKKYQRKGTFLRHMRTH---MDGQS 153

  Fly   262 FMCILCGNVFYKKSVFTAHMMTHSEYKPHQCEICNKSFRQMGELRAHIRRHTGDRPYKCMYCDRH 326
            |.|..|...|..:....|||.||:..||::|..|.|:|.|...|::|.|.|||:||:||..|.:.
  Fly   154 FPCPYCKRNFRLRVTLKAHMKTHNAAKPYECSHCAKTFAQQSTLQSHERTHTGERPFKCSQCSKT 218

  Fly   327 FYDRSERVRHERVHTNTRPYACQECGKTFTHTAILKNHILSHSAQKNYNCGICCKSFTLLHQLKA 391
            |...|:..||.|.|.:.||:.|.:|.||||....|.||..||:.::.:.|..|.|:|.:...||.
  Fly   219 FIKSSDLRRHIRTHGSERPFKCSKCTKTFTRKFHLDNHFRSHTGERPFKCSHCPKAFAMKQHLKQ 283

  Fly   392 H 392
            |
  Fly   284 H 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14710	NP_650092.4	zf-AD	9..83	CDD:285071	18/80 (23%)
		COG5048	<261..395	CDD:227381	53/132 (40%)
		C2H2 Zn finger	264..284	CDD:275368	6/19 (32%)
		zf-C2H2	290..312	CDD:278523	8/21 (38%)
		C2H2 Zn finger	292..312	CDD:275368	8/19 (42%)
		zf-H2C2_2	304..327	CDD:290200	11/22 (50%)
		C2H2 Zn finger	320..340	CDD:275368	7/19 (37%)
		zf-H2C2_2	335..357	CDD:290200	11/21 (52%)
		C2H2 Zn finger	348..368	CDD:275368	9/19 (47%)
		C2H2 Zn finger	376..395	CDD:275368	7/17 (41%)
CG15436	NP_608840.1	zf-AD	4..78	CDD:285071	18/108 (17%)
		C2H2 Zn finger	128..148	CDD:275368	3/20 (15%)
		C2H2 Zn finger	156..176	CDD:275368	6/19 (32%)
		COG5048	<180..341	CDD:227381	44/105 (42%)
		C2H2 Zn finger	184..204	CDD:275368	8/19 (42%)
		zf-H2C2_2	197..219	CDD:290200	11/21 (52%)
		C2H2 Zn finger	212..232	CDD:275368	7/19 (37%)
		zf-H2C2_2	224..249	CDD:290200	11/24 (46%)
		C2H2 Zn finger	240..260	CDD:275368	9/19 (47%)
		zf-H2C2_2	252..276	CDD:290200	8/23 (35%)
		C2H2 Zn finger	268..288	CDD:275368	7/17 (41%)
		C2H2 Zn finger	296..316	CDD:275368
		C2H2 Zn finger	324..341	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446581
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I1804
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.890