DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14710 and Zkscan4

DIOPT Version :9

Sequence 1:	NP_650092.4	Gene:	CG14710 / 41393	FlyBaseID:	FBgn0037920	Length:	415	Species:	Drosophila melanogaster
Sequence 2:	XP_038952138.1	Gene:	Zkscan4 / 291164	RGDID:	1309004	Length:	480	Species:	Rattus norvegicus

Alignment Length:	326	Identity:	86/326 - (26%)
Similarity:	143/326 - (43%)	Gaps:	53/326 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 DEQQEDQSQEVLDFNGFIINESIEEDE------EPNTESPEQI--LISHMDSYVDD--------Q 177
            |...::|..|:|....|:   :|...|      |.:.:|.|::  |:.::|..:|:        :
  Rat    83 DMHSKEQILELLVLEQFL---TILPGELQAWVREQHPDSGEEVVALLEYLDRQLDETPPQVPTGE 144

  Fly   178 QMEELIDDKGELVEELSNANTFYE------VEYGDEELLMSSAPSPHPSFKMDKQKPGRP----- 231
            ...||:..|..||....::.:.:.      .::..:|.|..| |......:|..:..|.|
  Rat   145 WSRELLCCKVALVTSSQDSQSSHSQAMKSLFKHESQESLECS-PLQARGLEMKPETRGLPLAEEY 208

  Fly   232 --RKPDAELKFKRKDI------------NAKERGNQPKCKEEEKFMCILCGNVFYKKSVFTAHMM 282
              :||:..:.|..:|.            ..|.:..|.......:|.|..||..|.:.|..|.|..
  Rat   209 KEQKPEQTVWFLGEDTVQISTSTEASEQEGKLQTTQKNATGNRRFYCHECGKSFAQSSGLTKHKR 273

  Fly   283 THSEYKPHQCEICNKSFRQMGELRAHIRRHTGDRPYKCMYCDRHFYDRSERVRHERVHTNTRPYA 347
            .|:..||::||.|.|:|.....|..|.|.|||::||:|..|.:.|...|..::|:|.||..:||.
  Rat   274 IHTGEKPYECEDCGKTFIGSSALVIHQRVHTGEKPYECEECGKVFSHSSNLIKHQRTHTGEKPYE 338

  Fly   348 CQECGKTFTHTAILKNHILSHSAQKNYNCGICCKSFTLLHQLKAHLQTLTHRNKMEQTIPSSPEM 412
            |.:||||||.:..|..|...|:.:|.:.|.:|.|:|.....|..|.:  .|.:|      ::|::
  Rat   339 CDDCGKTFTQSCSLLEHHKIHTGEKPFQCNLCGKAFRRSSHLLRHQR--IHGDK------AAPKL 395

  Fly   413 L 413
            |
  Rat   396 L 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14710	NP_650092.4	zf-AD	9..83	CDD:285071
		COG5048	<261..395	CDD:227381	51/133 (38%)
		C2H2 Zn finger	264..284	CDD:275368	7/19 (37%)
		zf-C2H2	290..312	CDD:278523	8/21 (38%)
		C2H2 Zn finger	292..312	CDD:275368	8/19 (42%)
		zf-H2C2_2	304..327	CDD:290200	10/22 (45%)
		C2H2 Zn finger	320..340	CDD:275368	6/19 (32%)
		zf-H2C2_2	335..357	CDD:290200	12/21 (57%)
		C2H2 Zn finger	348..368	CDD:275368	9/19 (47%)
		C2H2 Zn finger	376..395	CDD:275368	6/18 (33%)
Zkscan4	XP_038952138.1	SCAN	47..156	CDD:128708	16/75 (21%)
		zf-C2H2	253..275	CDD:395048	8/21 (38%)
		C2H2 Zn finger	255..275	CDD:275368	7/19 (37%)
		zf-H2C2_2	268..290	CDD:404364	9/21 (43%)
		zf-C2H2	281..303	CDD:395048	8/21 (38%)
		C2H2 Zn finger	283..303	CDD:275368	8/19 (42%)
		COG5048	<307..471	CDD:227381	33/98 (34%)
		C2H2 Zn finger	311..331	CDD:275368	6/19 (32%)
		C2H2 Zn finger	339..359	CDD:275368	9/19 (47%)
		C2H2 Zn finger	367..387	CDD:275368	6/21 (29%)
		C2H2 Zn finger	422..442	CDD:275368
		C2H2 Zn finger	450..470	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910