Protein Alignment CG14710 and ZNF765-ZNF761

DIOPT Version :10

• Sequence 1: NP_650092.4
• Gene: CG14710 / 41393
• FlyBaseID: FBgn0037920
• Length: 415
• Species: Drosophila melanogaster
• Sequence 2: NP_001337425.1
• Gene: ZNF765-ZNF761 / 110116772
• -ID: -
• Length: 746
• Species: Homo sapiens
• Alignment Length: 412
• Identity: 106/412 - (25%)
• Similarity: 165/412 - (40%)
• Gaps: 115/412 - (27%)

  Fly    63 FVQMWFNFRQMCLN-SQVYWETSSSERPEALAQASDAEY---MLYLYENL-HLKLGTENQEKEEI 122
            |.|....||.:.:. ||..|        :.|..|....|   ||..|.|| .|.:.::...||.:
Human     3 FSQGLLTFRDVAIEFSQEEW--------KCLDPAQRTLYRDVMLENYRNLVSLDISSKCTMKEFL 59

  Fly   123 TAIE------------------EGDEQQEDQSQEVLDFNGFIINESIEEDEEPNTESP------- 162
            :..:                  .||...:|..:::.|:     ....:|||....|:|
Human    60 STAQGNREVFHAGTLQIHESHHNGDFCYQDVDKDIHDY-----EFQWQEDERNGHEAPMTKIKKL 119

  Fly   163 ----EQILISH-MDSYVDDQ---------------QMEELIDDKGELVEELSNANTFYEVEYGDE 207
                |:...|| .:..:.||               |.||.||:  ::|:.:.:|:
Human   120 TGITERYDQSHARNKPIKDQLGSSFHSHLPEMHIFQTEEKIDN--QVVKSVHDAS---------- 172

  Fly   208 ELLMSSA------PSPHPSFKMDKQKPGRPRKPDAELKFKRKDINAKERGNQPKCKEE------- 259
              |:|:|      |..|.|     ...|. ...::.|..::::::.:|:..|  |.|.
Human   173 --LVSTAQRISCRPKTHIS-----NNHGN-NFWNSSLLTQKQEVHMREKSFQ--CNESGKAFNYS 227

  Fly   260 ------------EKFMCILCGNVFYKKSVFTAHMMTHSEYKPHQCEICNKSFRQMGELRAHIRRH 312
                        :|:.|.:||.:|.:|.....|...|:...|::|..|.|:|.|...|..|.|.|
Human   228 SLLRKHQIIHLADKYKCDVCGKLFNQKRNLACHRRCHTGENPYKCNECGKTFSQTSSLTCHRRLH 292

  Fly   313 TGDRPYKCMYCDRHFYDRSERVRHERVHTNTRPYACQECGKTFTHTAILKNHILSHSAQKNYNCG 377
            ||::||||..||:.|:.:|...||..:||..:||.|.||||||...:||..|...|:.:|.|.|.
Human   293 TGEKPYKCEECDKAFHFKSILERHRIIHTEEKPYKCNECGKTFRQKSILTRHHRLHTGEKPYKCN 357

  Fly   378 ICCKSFTLLHQLKAHLQTLTHR 399
            .|.|:|:....|..|     ||
Human   358 ECGKTFSHKSSLTCH-----HR 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14710	NP_650092.4	zf-AD	9..84	CDD:462262	7/21 (33%)
		COG5048	<261..395	CDD:227381	53/133 (40%)
		C2H2 Zn finger	264..284	CDD:275368	6/19 (32%)
		C2H2 Zn finger	292..312	CDD:275368	8/19 (42%)
		C2H2 Zn finger	320..340	CDD:275368	7/19 (37%)
		C2H2 Zn finger	348..368	CDD:275368	10/19 (53%)
		C2H2 Zn finger	376..395	CDD:275368	6/18 (33%)
ZNF765-ZNF761	NP_001337425.1	KRAB	7..48	CDD:460171	13/48 (27%)
		C2H2 Zn finger	217..237	CDD:275368	2/19 (11%)
		COG5048	242..617	CDD:227381	54/138 (39%)
		C2H2 Zn finger	244..264	CDD:275368	6/19 (32%)
		C2H2 Zn finger	272..292	CDD:275368	8/19 (42%)
		C2H2 Zn finger	300..320	CDD:275368	7/19 (37%)
		C2H2 Zn finger	328..348	CDD:275368	10/19 (53%)
		C2H2 Zn finger	356..376	CDD:275368	8/24 (33%)
		C2H2 Zn finger	384..404	CDD:275368
		C2H2 Zn finger	412..432	CDD:275368
		C2H2 Zn finger	440..460	CDD:275368
		C2H2 Zn finger	468..488	CDD:275368
		C2H2 Zn finger	496..516	CDD:275368
		C2H2 Zn finger	524..544	CDD:275368
		C2H2 Zn finger	552..572	CDD:275368
		C2H2 Zn finger	580..600	CDD:275368
		C2H2 Zn finger	608..628	CDD:275368
		C2H2 Zn finger	636..656	CDD:275368
		zf-H2C2_2	648..673	CDD:463886
		SFP1	<651..737	CDD:227516
		C2H2 Zn finger	664..684	CDD:275368
		C2H2 Zn finger	692..712	CDD:275368
		C2H2 Zn finger	720..740	CDD:275368