DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6791 and Sry-delta

DIOPT Version :9

Sequence 1:	NP_650090.1	Gene:	CG6791 / 41391	FlyBaseID:	FBgn0037918	Length:	1243	Species:	Drosophila melanogaster
Sequence 2:	NP_524581.1	Gene:	Sry-delta / 43572	FlyBaseID:	FBgn0003512	Length:	433	Species:	Drosophila melanogaster

Alignment Length:	433	Identity:	93/433 - (21%)
Similarity:	149/433 - (34%)	Gaps:	163/433 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 SDFEEGEAESG----VAELE----DSEQYGNGNDDFLGDTAILDSGDAIDDLLDAEEDEREEEDD 69
            |:||  ..|||    |.|:|    |.|...:...|.|....:.|..::..::.....||.|||||
  Fly    95 SEFE--VPESGEDILVEEVEIPQSDVETDADAEADALFVELVKDQEESDTEIKREFVDEEEEEDD 157

  Fly    70 YEKNSKEPKQPDPDDDALFDFNMEPIVDIAEPQRPSLAPAGPMSQ-QVRPPMQRHSFPGAGGRPR 133
                       |.||:.:.:     .||:.:    |.|..|..|. :.||..:|
  Fly   158 -----------DDDDEFICE-----DVDVGD----SEALYGKSSDGEDRPTKKR----------- 191

  Fly   134 LGSGLSVRPTTS----------QINATDENGVPINYELGVVYICPACGGEFRQQDHWKRHMNHIH 188
                :....||.          |.:.::|:....|      :|||.||...|.:::.:.||| :|
  Fly   192 ----VKQECTTCGKVYNSWYQLQKHISEEHSKQPN------HICPICGVIRRDEEYLELHMN-LH 245

  Fly   189 K-----------------YNTLRGLNFTPLDKLYQRCRECNKRIAMHSRENLL-KHKFTH----- 230
            :                 .||||.:......|.|| |.:|..|.   |::||| .|:..|
  Fly   246 EGKTEKQCRYCPKSFSRPVNTLRHMRMHWDKKKYQ-CEKCGLRF---SQDNLLYNHRLRHEAEEN 306

  Fly   231 --------LPFRCTK-----------------CYICKREYKYRQDLMVHLRMVHCDEVVAMMREG 270
                    :.|:..|                 |.:|.:.:..|..|.:|:: .|..:||
  Fly   307 PIICSICNVSFKSRKTFNHHTLIHKENRPRHYCSVCPKSFTERYTLKMHMK-THEGDVV------ 364

  Fly   271 YNAAGRKTRVRESRTEQLLREKSFRENDDLGEESDRIEVRNELLEPDADESGTQEQTVSEEVSKK 335
            |.                :||::..:...:.||          |..|.|||......:..: :.:
  Fly   365 YG----------------VREEAPADEQQVVEE----------LHVDVDESEAAVTVIMSD-NDE 402

  Fly   336 KAGTRGAAELCEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYV 378
            .:|              .|..|.|:.:...:...|::|.||.|
  Fly   403 NSG--------------FCLICNTNFENKKELEHHLQFDHDVV 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6791	NP_650090.1	C2H2 Zn finger	167..188	CDD:275368	8/20 (40%)
		C2H2 Zn finger	208..230	CDD:275368	8/22 (36%)
		C2H2 Zn finger	235..256	CDD:275368	6/37 (16%)
		C2H2 Zn finger	516..532	CDD:275368
		C2H2 Zn finger	557..580	CDD:275368
		C2H2 Zn finger	589..609	CDD:275368
		COG5236	<939..>1096	CDD:227561
Sry-delta	NP_524581.1	COG5048	<205..360	CDD:227381	36/166 (22%)
		C2H2 Zn finger	225..245	CDD:275368	8/20 (40%)
		C2H2 Zn finger	253..273	CDD:275368	4/19 (21%)
		C2H2 Zn finger	281..301	CDD:275368	8/22 (36%)
		C2H2 Zn finger	310..327	CDD:275370	2/16 (13%)
		zf-C2H2	337..359	CDD:278523	5/22 (23%)
		C2H2 Zn finger	339..359	CDD:275368	5/20 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455506
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030