Protein Alignment CG6791 and hang

DIOPT Version :10

• Sequence 1: NP_650090.1
• Gene: CG6791 / 41391
• FlyBaseID: FBgn0037918
• Length: 1243
• Species: Drosophila melanogaster
• Sequence 2: NP_001138204.1
• Gene: hang / 32613
• FlyBaseID: FBgn0026575
• Length: 2223
• Species: Drosophila melanogaster
• Alignment Length: 1662
• Identity: 301/1662 - (18%)
• Similarity: 467/1662 - (28%)
• Gaps: 637/1662 - (38%)

  Fly    54 DDLLDAEEDER----EEEDD-------YEKNSKEPKQP----DPDDDALFDFNMEPIVDIAEPQR 103
            |:.:|.::|.:    :|.||       .|::..|...|    |.|..|....|...:.....|..
  Fly   505 DEPIDTDDDYQMKSIDESDDMVDPTMFLERSEHEGDVPLTASDYDYTAQHGVNASSVAASLPPNA 569

  Fly   104 -PSLAPAG----------PMSQQVRPPMQRHSFPGAGGRPRLGSGLSVRPTTSQINATDENGVPI 157
             .::|.||          .:....|...:||.             .::.|...|::....:..||
  Fly   570 VANVAAAGDSKVASCRACSLQFSTRANARRHE-------------RNLHPNLFQLSTDSPHNTPI 621

  Fly   158 -------------------------NYELGVVYICPACGGEFRQQDHWKRHMNHIHK-----YNT 192
                                     |...|      |.||....|.:.:..||...|     |:.
  Fly   622 TKPTPALAAALEMQRAAAAAATAEANRAAG------AAGGNISTQKYRQVVMNAFIKCEGGGYDY 680

  Fly   193 LRGLNFTPL---DKL------------YQ--RCRECNKRIAMHSRENLLKH---KFTHLPFRCTK 237
            .....:.||   ||:            ||  .||.|||..:.:  :|.:.|   |:..||...
  Fly   681 DNPEQYRPLLTRDKVEFIEQNDEFLEQYQTMTCRCCNKYFSTY--KNFMAHVRKKYPQLPRNL-- 741

  Fly   238 CYICKREYKYRQDLMVHLRMVHCDEVVAMMREGYNA-AGRKTRVRESRTEQLLREKSFRENDDLG 301
            |:.|.:....:...:.||:..:|..:..::    || .|:.|.|.....            ||:.
  Fly   742 CFNCLKMNDSKALFISHLKKRNCINLFRVL----NALRGKTTTVVVPIA------------DDVA 790

  Fly   302 EESDRIEVRNELLEPDADES------GTQEQTVSEEVSKKKAGTR-----GAAELCEDYIHYMCP 355
            ::.....:      |.||..      .:...|.|.||.....|:.     .|.||..:.: |.|.
  Fly   791 DDGATGSI------PVADAGAGVVAMNSPTVTASGEVVTPGGGSERPEKLRAKELLVNKL-YECK 848

  Fly   356 DCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRSVDMQMQCLEC-KKIVTPNTIKSLRAHKFSHLSQ 419
            .|.....|..::..|:...|..|.|:..|      .:||..| .....|..    |...::::..
  Fly   849 LCPKGFRTKHEFRTHVYDKHADVQRKDNN------SIQCSFCGLDFADPVD----RRRHYNNMDC 903

  Fly   420 PEWLRCKLCYKGYTDHQEIIRHLLQQHHMDT---LMSEDAEEE-DGDAPSAIEDECDGDNG--NG 478
            ...|||..|......||..:.|:.|.|....   .:|::|... .|.|.|...:...|...  ..
  Fly   904 IVRLRCMTCDAKLETHQRFLDHVYQDHLGGVGGGAVSDNASTTGSGMARSNSMEHSPGKRSLLGA 968

  Fly   479 EGNGAPLDED-----SPYFEDAPR--------RGGRISSD-----------DIFEPHIDY----- 514
            .|.|:..:|.     :|.....|:        .||..|:.           |...|...|
  Fly   969 LGVGSSAEESRSSSAAPPLTSTPKLAGGNQVGGGGSTSASAAAAAQSSANRDASAPKSQYFSRMP 1033

  Fly   515 -LCPQCGKEFIEKKHWRTHVVMAHSMNDLSKLNFEMINERQLKCTECDKIITNAYGIQNAQQHRI 578
             :||.||:::                                          |.|  .|..:|..
  Fly  1034 QVCPICGQQY------------------------------------------NNY--NNVLRHME 1054

  Fly   579 THLPFK---AYARCRKCHKSYTDRKGLVKHLATHHRVGWPRKLSGG------CPAPILTPAKQPR 634
            :..|.|   .| :|.:|...|.....|.:|:...|.|...|. |||      ..|..|.....|
  Fly  1055 SKHPNKLPETY-KCVRCGLGYPRISYLREHMINVHGVDKNRH-SGGFEYIVNADAVKLADGSTP- 1116

  Fly   635 KQIVTVANETYEIIYLD--DVDQGGMEEDNDFGEQMQAEEDEYPIAPPPPSPPPPPQPTTQGNH- 696
                .|....|:.:..|  .:..||..:|         ||:|      |.|.....:.....|:
  Fly  1117 ----NVYTGRYDYVMKDLMSITNGGTLDD---------EEEE------PGSVAKKMRLDDSSNNS 1162

  Fly   697 -------QRYKCVHCGTLFATQAAVRVHISEKRCRKTVVR------RRRQP-------------- 734
                   |:.:|..|..:|:....:..|:.........|.      .|..|
  Fly  1163 SLVGVASQQKECPICNAVFSNNIGLSNHMRSHYTASNAVNAALAAANRMTPKSLTITATPATDSE 1227

  Fly   735 -----VMSSADPSVP----------TVEQNYIF---------------LCPSCGFEYKTQFEWRR 769
                 .||.:.|:.|          |.::..:|               .|..|...:.::..:|.
  Fly  1228 LGVGGTMSESAPATPANVPPAMANQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRY 1292

  Fly   770 HINEVHNFDKRQYLNMRQLDKYRYQCTQCKDIVCNSKL---KGLQDH----HFRHLPYRLYLK-- 825
            |:...|.....|::             :||  :||::.   |||:.|    |.:.:...:.:|
  Fly  1293 HMLTDHQVQNVQFI-------------KCK--LCNAEFAYEKGLKVHLFKVHGKAIKDEMIIKQF 1342

  Fly   826 -CLICGTCYNHKPNIAAHLRARHSIFDRETPTMITKPKQVLGRYKDNSRENPKLPSPPPAPALAP 889
             |.:|...|:.:..:..|.|:.|.:......|..:...::    .|:|..:...|:
  Fly  1343 ECDVCSIVYSSESELQQHKRSVHKLTSASASTSASTSSKI----DDDSLMDDGKPT--------- 1394

  Fly   890 APPSPPACSSSAAASASSRSLKPQPGGLPARPAGLNT---LEDSISYHNAVDLDFITYFCPKCNQ 951
              .|..|..|:.||..|:.|...........|:..||   |...|:.|:  :.|...|.|..|..
  Fly  1395 --SSDLADLSTLAAGGSTASAPLYWYQCKYCPSNFNTNKKLAIHINSHD--EFDSNDYSCKDCGN 1455

  Fly   952 NFDSHAFWRKHIVEQHNF--NSREGLNFRQI-------DNHHYLCLECYKRVTVTHTKGA----I 1003
            .:........|..::|..  |..|....|::       |||...|    .|..:|.| ||    .
  Fly  1456 VYSGRKSLWVHRYKKHPQVPNPAECSLCRKVFFDRQMHDNHTPTC----NRKPITST-GAHQQQD 1515

  Fly  1004 GQLQSHK------FRH----------------LPHR----------------------SFK---- 1020
            |||.||.      |||                |..|                      |.|
  Fly  1516 GQLHSHHTAKRTIFRHKTGDDDDEEDDDEQQQLEERANSDGNGTTVGVASGSTAAAGTSLKIRIP 1580

  Fly  1021 ---CLTCGGEFVRKQMFFKHLNRDTNR--CDNRPHREFDDDEPD----QDTLLSTIYHLTCPQCG 1076
               |..||..|..::.|.||:.:....  .||.....|||...|    |....:......|..|.
  Fly  1581 EVACTICGARFTDQEHFSKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCA 1645

  Fly  1077 DNF------KTHNKKEWR------------------EHINDHHGLTKLELLHMTKVG-------- 1109
            ..|      |.|.|..:|                  .|..:::....:.|..:..||
  Fly  1646 KTFPQVIALKVHRKWHFRGDSKQNPIDGEATQLTNNNHTTNNNNNNSMHLRELHAVGLMPNQQQQ 1710

  Fly  1110 --------------------------EDVYRCQDCDEELETN-----RQWVLQFHRFQHLP---- 1139
                                      :...:|:.|.....:|     ..:.|..|...:||
  Fly  1711 SLNNSCNSSMNHNNNSSSNRSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPV 1775

  Fly  1140 -----HAAYIRCKL--------CKQSSAD------------GADAVGELHSLRE-LQQHIRKH-- 1176
                 |....||:|        .:...||            |.|..||..|.:| |..||..|
  Fly  1776 IVVDDHLTCRRCQLKFDTKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLMNHINNHLK 1840

  Fly  1177 -------------------HPGLGDAEMISLIEQIIQ---------------------------- 1194
                               .....||...:.:..:.:
  Fly  1841 EEVIVPVATKAAIERTAAMESAAADANAAATLSALGEGAETEDQFAEKVEAAGATTTDKLTNPDE 1905

  Fly  1195 -----------------------------DEKEQEEGTEQTNDGENPTGQDSGPYMPLPPHLL-- 1228
                                         |:.|..||.::..:|:...|:|.....| |..||
  Fly  1906 EDSDDLDEDSSGDDDDSSGTGDDDDDDDSDDDEDGEGEDEDEEGDGGEGEDEEGVQP-PAQLLPQ 1969

  Fly  1229 ---------------------------DDDGDVEFED 1238
                                       ||||:||.:|
  Fly  1970 QQHKTDLNLNQDDDDLVEEVISSDDDEDDDGEVESDD 2006

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6791	NP_650090.1	C2H2 Zn finger	167..188	CDD:275368	6/20 (30%)
		C2H2 Zn finger	208..230	CDD:275368	8/24 (33%)
		C2H2 Zn finger	235..256	CDD:275368	3/20 (15%)
		C2H2 Zn finger	516..532	CDD:275368	4/15 (27%)
		C2H2 Zn finger	557..580	CDD:275368	4/22 (18%)
		C2H2 Zn finger	589..609	CDD:275368	5/19 (26%)
		COG5236	<939..>1096	CDD:227561	52/250 (21%)
hang	NP_001138204.1	zf-AD	80..154	CDD:462262
		C2H2 Zn finger	1036..1057	CDD:275368	8/64 (13%)
		C2H2 Zn finger	1067..1088	CDD:275368	5/20 (25%)
		C2H2 Zn finger	1279..1298	CDD:275371	3/18 (17%)
		C2H2 Zn finger	1308..1325	CDD:275371	7/18 (39%)
		C2H2 Zn finger	1420..1440	CDD:275368	5/19 (26%)
		C2H2 Zn finger	1450..1468	CDD:275368	3/17 (18%)