DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6791 and CG2120

DIOPT Version :9

Sequence 1:	NP_650090.1	Gene:	CG6791 / 41391	FlyBaseID:	FBgn0037918	Length:	1243	Species:	Drosophila melanogaster
Sequence 2:	NP_572446.2	Gene:	CG2120 / 31737	FlyBaseID:	FBgn0030005	Length:	315	Species:	Drosophila melanogaster

Alignment Length:	372	Identity:	67/372 - (18%)
Similarity:	113/372 - (30%)	Gaps:	143/372 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   294 FRENDDLGEESDRIEVRNELLEPDAD-------ESGTQEQTVSEE-----------VSKKKAGTR 340
            |.:.:||..|  |:.:..|||.|.::       ....|::..:|.           .:.|:..|.
  Fly    33 FAQLEDLSGE--RLPMEMELLNPGSEYDLLELVNGALQQRNTTEHKPTDMCKPKRTPTTKRHRTT 95

  Fly   341 GAAELC--------EDY---IHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRSVDMQMQC 394
            |....|        |.|   ||.|         ||.....|:                      |
  Fly    96 GKDHTCDICDRRFSEAYNLRIHKM---------THTDEKPHV----------------------C 129

  Fly   395 LECKKIVTPNTIKSLRAHKFSHLSQ-PEWLRCKLCYKGY------TDHQEIIR------------ 440
            :||.|..  ..:..||.|..:|.:: |.  :|.:|.||:      |.|:.:..
  Fly   130 VECGKGF--RQLNKLRIHAVTHTAERPH--KCDICGKGFRYANYLTVHRRLHTGEKPYPCLATDC 190

  Fly   441 ----HLLQQHHMDTLMSEDAEEEDGDAPSAIEDECDGDNGNGEGNGAPLDEDSPYFEDAPRRGGR 501
                |.:....:.|.:...|:.:.                         |.:.|..|...|....
  Fly   191 HLSFHSIHARRIHTKLRHAAQTDP-------------------------DPEHPLAEQEQRDTSA 230

  Fly   502 ISSDDIFEPHIDYLCPQCGKEFIEKKHWRTHVVMAHSMNDLSKLNFEMINERQLKC--TECDKII 564
            :|          :.||.|.:...::.:...|:          |.::   |:|...|  .||.|
  Fly   231 LS----------FTCPVCSRVLTDQCYLSIHL----------KRHY---NQRDFPCPQPECGK-- 270

  Fly   565 TNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLATHHR 611
             ..:.....:.|:|.|...:.:| |..|...:..:....:||..|.|
  Fly   271 -RFFSASELKHHQIAHTQQRPFA-CPLCPARFLRKSNHKQHLKVHER 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6791	NP_650090.1	C2H2 Zn finger	167..188	CDD:275368
		C2H2 Zn finger	208..230	CDD:275368
		C2H2 Zn finger	235..256	CDD:275368
		C2H2 Zn finger	516..532	CDD:275368	3/15 (20%)
		C2H2 Zn finger	557..580	CDD:275368	6/24 (25%)
		C2H2 Zn finger	589..609	CDD:275368	4/19 (21%)
		COG5236	<939..>1096	CDD:227561
CG2120	NP_572446.2	C2H2 Zn finger	101..121	CDD:275368	6/28 (21%)
		zf-H2C2_2	113..138	CDD:290200	10/57 (18%)
		C2H2 Zn finger	129..149	CDD:275368	7/21 (33%)
		zf-H2C2_2	142..166	CDD:290200	9/25 (36%)
		COG5048	151..>264	CDD:227381	22/162 (14%)
		C2H2 Zn finger	157..177	CDD:275368	6/19 (32%)
		C2H2 Zn finger	185..206	CDD:275368	2/20 (10%)
		C2H2 Zn finger	235..255	CDD:275368	5/29 (17%)
		C2H2 Zn finger	263..285	CDD:275368	6/24 (25%)
		C2H2 Zn finger	293..313	CDD:275368	4/19 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100