DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wkd and GYP5

DIOPT Version :9

Sequence 1:	NP_650089.1	Gene:	wkd / 41390	FlyBaseID:	FBgn0037917	Length:	363	Species:	Drosophila melanogaster
Sequence 2:	NP_015075.1	Gene:	GYP5 / 855827	SGDID:	S000006170	Length:	894	Species:	Saccharomyces cerevisiae

Alignment Length:	267	Identity:	70/267 - (26%)
Similarity:	123/267 - (46%)	Gaps:	32/267 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 WLYMIDNWSIYMSKNYKKIRDRCRKGIPKSVRPKAWFYLSGAYLLKKKNPNVYNELLEKPGNPTT 116
            |..::::::...|...:.:......|||..:|...|..::.:  ..::..::|..||:    ...
Yeast   426 WTQVVNDYATVASNEPENLEAHVTNGIPPQIRGIIWQLMANS--KSREMEDIYETLLD----TEC 484

  Fly   117 IEE--IKKDKHRQFPFHEMFLDEQKVGQIELFNVLKAYSIYNPKVGFCQAQAPIAAFLLMHLPAE 179
            :.|  |::|..|     ..|:.|.|:.  .|:.|:|.||:|:|.||:.|....|||.||::...|
Yeast   485 LHEATIRRDLRR-----TKFVAEDKME--SLYKVIKVYSVYDPDVGYTQGMGFIAAPLLINCENE 542

  Fly   180 -DAFWVFVSVCDVY-LQDYFIPGLEVIQNDAGILEGLLKKTCPPVYRHLQKHKVEPLLYMTDWFL 242
             ::|.:.|.:...| |::.|:||:..:.......:.||::..|.:|..|.:..:...:|.|.|||
Yeast   543 AESFGLLVGLMKNYGLRELFLPGMPGLMLMLYQFDRLLEEHSPSLYNRLIREGISSTMYATQWFL 607

  Fly   243 CAMTRTLPWETLLRVWDCFLAEGIRVIFKVALVIIGASLSRHKVRKTCTGLCETLAVLRSPE--E 305
            .......|.|.:||::|....|||.|:.|.|   :...|...          |||..||..|  :
Yeast   608 TFFAYKFPLEFVLRIFDIVFVEGIEVLLKFA---VNLMLKNE----------ETLVKLRFDELLD 659

  Fly   306 HIVEEEF 312
            .:.:|.|
Yeast   660 FLKDELF 666

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wkd	NP_650089.1	RabGAP-TBC	114..277	CDD:366170	51/166 (31%)
GYP5	NP_015075.1	COG5210	154..737	CDD:227535	70/267 (26%)
GYP5	NP_015075.1	SMC_prok_B	726..>891	CDD:274008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810