Protein Alignment wkd and MSB4

DIOPT Version :9

• Sequence 1: NP_650089.1
• Gene: wkd / 41390
• FlyBaseID: FBgn0037917
• Length: 363
• Species: Drosophila melanogaster
• Sequence 2: NP_014529.1
• Gene: MSB4 / 854037
• SGDID: S000005472
• Length: 492
• Species: Saccharomyces cerevisiae
• Alignment Length: 347
• Identity: 88/347 - (25%)
• Similarity: 140/347 - (40%)
• Gaps: 75/347 - (21%)

  Fly    48 REKKWLYMI---------DNWSIYMSKNYKKIRDRCRKGIPKSVRPKAWFYLSGAYLLKKKNPNV 103
            |:|||...:         ||..:|.::. .::....|||||...|..||:|.:|.......|..|
Yeast   110 RKKKWENFLLKNKIELHNDNPLVYPART-DELSKFVRKGIPAEWRGNAWWYFAGGQRQLDANVGV 173

  Fly   104 YNEL----LEKPGNPTTIEEIKKDKHRQFP----FH-EMFLDEQKVGQIELFNVLKAYSIYNPKV 159
            |:.|    .|...:...:|.|::|.:|.||    || |.|.:.:......|..||.|:|:|:..:
Yeast   174 YDRLKSDCREGAVSGKDMEAIERDLYRTFPDNIHFHKESFQNGEPAIIRSLRRVLMAFSVYDKTI 238

  Fly   160 GFCQAQAPIAAFLLMHLPAEDAFWVFVSVCDVYLQDYFIPGLEVIQNDAGILEGLLKKTCPPVYR 224
            |:||:...:...||:.:..|.|||:.|.:...||...:...||....|.|:|...:|:..|.::.
Yeast   239 GYCQSMNFLVGLLLLFMEEEKAFWMLVIITGKYLPGVYESDLEGANVDQGVLVLCIKEYLPEIWS 303

  Fly   225 HLQKHKVE---------------------PLLYM--TDWFLCAMTRTLPWETLLRVWDCFLAEGI 266
            |::...:.                     |.|.:  ..||:......:|.||.||:|||...|..
Yeast   304 HIESSYMNGNGSTDQISGPASGEEYLCRLPTLTLCTASWFMSCFVGVVPIETTLRIWDCLFYEES 368

  Fly   267 RVIFKVALVIIGASLSRHKVRKTCTGLCETLAVLRSPEEHIVEEEFIINNMMRLNLRVEDFQIEH 331
            ..:|||||.|:..|                            |.||:.:...:|..:...:....
Yeast   369 HFLFKVALGILKLS----------------------------ESEFLESKSQKLFRQYSSYTFGG 405

  Fly   332 TRQ-----KARRAKQKAQQEAE 348
            :..     |..:.|.|.|:||:
Yeast   406 SNDSDSTFKRLKNKIKTQEEAD 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wkd	NP_650089.1	RabGAP-TBC	114..277	CDD:366170	54/190 (28%)
MSB4	NP_014529.1	COG5210	<53..461	CDD:227535	88/347 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R540
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840