Protein Alignment wkd and Tbc1d2b

DIOPT Version :10

• Sequence 1: NP_650089.1
• Gene: wkd / 41390
• FlyBaseID: FBgn0037917
• Length: 363
• Species: Drosophila melanogaster
• Sequence 2: NP_919315.2
• Gene: Tbc1d2b / 67016
• MGIID: 1914266
• Length: 965
• Species: Mus musculus
• Alignment Length: 272
• Identity: 80/272 - (29%)
• Similarity: 135/272 - (49%)
• Gaps: 23/272 - (8%)

  Fly    27 YGGFQRTDKPKEPLSKAQIIAREKKWLYMIDN--------WSIYMSKNYKK-------IRDRCRK 76
            ||.....|..:|....|::.|.:.|.||:.||        |..|.:....:       :::..|.
Mouse   599 YGFRTVPDDDEEEKLVAKVRALDLKTLYLTDNQEVSTGVKWENYFASTMNREMACSPELKNLIRA 663

  Fly    77 GIPKSVRPKAWFYLSGAYLLKKKN---PNVYNELLEK---PGNPTTIEEIKKDKHRQFPFHEMFL 135
            |||...|.|.|.:....:..|.|:   |:.:..||:|   ..||.: ::|:.|..|..|.::.:.
Mouse   664 GIPHEHRSKVWKWCVDRHTRKFKDSMEPDYFQTLLQKALEKQNPAS-KQIELDLLRTLPNNKHYS 727

  Fly   136 DEQKVGQIELFNVLKAYSIYNPKVGFCQAQAPIAAFLLMHLPAEDAFWVFVSVCDVYL-QDYFIP 199
            .....|..:|.:||.|:|..||.:|:||....:.|..|::|..|||||..|::.:|:: :||:..
Mouse   728 SPTSEGIQKLRSVLLAFSWRNPDIGYCQGLNRLVAVALLYLDQEDAFWCLVTIVEVFMPRDYYTK 792

  Fly   200 GLEVIQNDAGILEGLLKKTCPPVYRHLQKHKVEPLLYMTDWFLCAMTRTLPWETLLRVWDCFLAE 264
            .|...|.|..:...||.:..|.::.|.:::||:..|...:|||.....::..:.|.::||.||.|
Mouse   793 TLLGSQVDQRVFRDLLSEKLPRLHTHFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYE 857

  Fly   265 GIRVIFKVALVI 276
            |.:|||:.||.:
Mouse   858 GPKVIFRFALAL 869

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wkd	NP_650089.1	TBC	74..278	CDD:214540	67/210 (32%)
Tbc1d2b	NP_919315.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27
		PH_TBC1D2A	36..144	CDD:269966
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..288
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	310..340
		CwlO1	345..>586	CDD:443091
		RabGAP-TBC	709..878	CDD:459855	52/162 (32%)