Protein Alignment wkd and TBC1D14

DIOPT Version :9

• Sequence 1: NP_650089.1
• Gene: wkd / 41390
• FlyBaseID: FBgn0037917
• Length: 363
• Species: Drosophila melanogaster
• Sequence 2: XP_011511809.1
• Gene: TBC1D14 / 57533
• HGNCID: 29246
• Length: 727
• Species: Homo sapiens
• Alignment Length: 403
• Identity: 94/403 - (23%)
• Similarity: 154/403 - (38%)
• Gaps: 138/403 - (34%)

  Fly    37 KEPLSKAQIIAREKKWL-------------------YMIDNW-SIYMSKNYKKIRDRCRKGIPKS 81
            |..|.:||   |.||.|                   .::.|| :::.|   :|:||...:|||.|
Human   347 KRELKEAQ---RRKKQLEERCRVEESIGNAVLTWNNEILPNWETMWCS---RKVRDLWWQGIPPS 405

  Fly    82 VRPKAWFYLSGAYLLKKKNPNVYNELL-----------------------EKPG-----NPTTIE 118
            ||.|.|....|..|      |:.:||.                       |..|     ...::|
Human   406 VRGKVWSLAIGNEL------NITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREASLE 464

  Fly   119 EIKKDKHRQFP----FHEMFL------------------DEQKVGQI-----------ELFNVLK 150
            .||.|..|.||    |.::.:                  :..|:.|:           .|.::|.
Human   465 LIKLDISRTFPNLCIFQQVLIFVDFRVGLQKSFQKRKERESTKLQQLWSWCLGGPYHDMLHSILG 529

  Fly   151 AYSIYNPKVGFCQAQAPIAAFLLMHLPAEDAFWVFVSVCDVYLQDYFIPGLEVIQNDAGIL---- 211
            ||:.|.|.||:.|..:.|||.|:::|...|||..|.::.:...|..|      .:.|.|::
Human   530 AYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAF------FRVDHGLMLTYF 588

  Fly   212 ---EGLLKKTCPPVYRHLQKHKVEPLLYMTDWFLCAMTRTLPWETLLRVWDCFLAEGIRVIFKVA 273
               |...::..|.::.|.:|:.:.|.:|:.||.....:::||.:...|:||.|..:|...:|:.|
Human   589 AAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTA 653

  Fly   274 LVIIGASLSRHKVRKTCTGLCETLAVLRSPEEHIVEEEFIINNMMRLNLRV-EDFQIEH------ 331
                                   |.:|:..|:.:.:.:||  :|.:...|: ||...|.
Human   654 -----------------------LGILKLFEDILTKMDFI--HMAQFLTRLPEDLPAEELFASIA 693

  Fly   332 TRQKARRAKQKAQ 344
            |.|...|.|:.||
Human   694 TIQMQSRNKKWAQ 706

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wkd	NP_650089.1	RabGAP-TBC	114..277	CDD:366170	49/202 (24%)
TBC1D14	XP_011511809.1	TBC	398..664	CDD:214540	67/300 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810