DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wkd and si:ch211-266k8.4

DIOPT Version :9

Sequence 1:	NP_650089.1	Gene:	wkd / 41390	FlyBaseID:	FBgn0037917	Length:	363	Species:	Drosophila melanogaster
Sequence 2:	XP_687788.5	Gene:	si:ch211-266k8.4 / 559362	ZFINID:	ZDB-GENE-131121-469	Length:	617	Species:	Danio rerio

Alignment Length:	431	Identity:	107/431 - (24%)
Similarity:	171/431 - (39%)	Gaps:	100/431 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LDTISLCSTVSSC--PDRNGFYGGFQRTDKPKEPLSKAQIIAREKKWLYMIDNWSIYMSKNYKKI 70
            |..:|..|:..||  |.|.....||   |:.....||    .|:||......::| |...|..|:
Zfish     3 LRRVSSSSSGKSCNKPRRRSSSVGF---DEFGFAFSK----KRDKKLQQRCHDYS-YPQPNPVKV 59

  Fly    71 RDRC---------------------RKGIPKSVRPKAWFYLSGAYLLKKKNPNVYNELLEKPGNP 114
            ::.|                     |.|||.::|.:.|..|.....|:..:...|.:...:...|
Zfish    60 KELCEFLSYWNGSSFICRSQIERFIRIGIPPAIRGRVWRCLLNIDSLRATSCFNYEDCQSEIRRP 124

  Fly   115 --------------------------------------TTIEEIKKDKHRQFPFHEMFLDEQK-- 139
                                                  |..::|..|..|.||.|...:.::.
Zfish   125 LVDLGVSEYSIISSIDSLVDTENEISSGQASSPQVADLTLFKQIALDLQRSFPTHRTLMGDRPEA 189

  Fly   140 -VGQIELFNVLKAYSIYNPKVGFCQAQAPIAAFLLMHLPAEDAFWVFVSVCD--VYLQDYFIPGL 201
             .||.:||.||.|::.|||.:|:.|..:.|||.|||.|..|:|||..|::.:  .||.:.|...:
Zfish   190 IEGQAKLFRVLSAFARYNPLIGYVQGMSYIAAVLLMILSEEEAFWALVALLEKPKYLSELFDSSM 254

  Fly   202 EVIQNDAGILEGLLKKTCPPVYRHLQKHKVEPLLYMTDWFLCAMTRTLPWETLLRVWDCFLAEGI 266
            :.||:.|.:...|||...|.:::||:...|..:.::..|||...|....|:::|.:||..:..|:
Zfish   255 KKIQHQALVFHQLLKHRKPLLFQHLETLGVSCVHFIMQWFLTLFTSLPCWDSVLAIWDLIMLHGL 319

  Fly   267 RVIFKVALVIIGASLSRHKVRKTCTGLCETLAV----LRSPEE---HIV---------EEEFIIN 315
            :.:|:..|.||....||      ...:.|...|    ||.|.:   |.|         .:|:.||
Zfish   320 QAVFRTGLTIILLLESR------IMNMTEEATVLPLLLRVPIDICHHRVLIPALWSTDLQEWEIN 378

  Fly   316 NMMRLNLRVEDFQIEHTRQKARRAKQKAQQEAESSGSGNGH 356
            .|..|.|.    :::.|:.:.:..|:..:....|...|..|
Zfish   379 CMNSLVLE----ELDSTQDEEKANKENTKISTASFSDGQLH 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wkd	NP_650089.1	RabGAP-TBC	114..277	CDD:366170	56/205 (27%)
si:ch211-266k8.4	XP_687788.5	RabGAP-TBC	166..338	CDD:278964	58/177 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D976276at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820