DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wkd and si:ch211-288d18.1

DIOPT Version :9

Sequence 1:	NP_650089.1	Gene:	wkd / 41390	FlyBaseID:	FBgn0037917	Length:	363	Species:	Drosophila melanogaster
Sequence 2:	XP_686696.2	Gene:	si:ch211-288d18.1 / 558401	ZFINID:	ZDB-GENE-060503-323	Length:	603	Species:	Danio rerio

Alignment Length:	326	Identity:	110/326 - (33%)
Similarity:	163/326 - (50%)	Gaps:	25/326 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 DRNGFYGGFQ-RTDKPKEPLSKAQIIAREKKWLYMIDNWSIYMSKNYKKIRDRCRKGIPKSVRPK 85
            ||.||....: .|....|...|...|.|.:|||.|:.|||.|  :|..::..|..||||..:|.:
Zfish    45 DRFGFLHEEELPTPSALEEKQKQVEIERVQKWLKMLKNWSKY--RNSDRMMKRVFKGIPLQLRGQ 107

  Fly    86 AWFYLSGAYLLKKKNPNVYNELLEKPG--NPTTIEEIKKDKHRQFPFHEMFLDEQKVGQIELFNV 148
            ||..|.....:|..|...|..:.|:..  :| .|::|..|.:|.|..|.||:|...|.|..||:|
Zfish   108 AWALLLDVEKVKSDNAGKYERMKEQAQLYSP-EIKQIDLDINRTFRNHIMFMDRFGVKQQSLFHV 171

  Fly   149 LKAYSIYNPKVGFCQAQAPIAAFLLMHLPAEDAFWVFVSVCDVY---LQDYFIPGLEVIQNDAGI 210
            |.|||:||.:|.:||..:.|||.|||.:..|||||....:....   :..:|:||...:|.....
Zfish   172 LSAYSVYNTEVSYCQGMSQIAAILLMFMNEEDAFWALSQLLTNQKHGMHGFFVPGFPKLQRFQNH 236

  Fly   211 LEGLLKKTCPPVYRHLQKHKVEPLLYMTDWFL-CAMTRTLPWETLLRVWDCFLAEGIRVIFKVAL 274
            .:.:|.|..|.:.:||.|.::...:|.|.||| |.:.|| |:...||:||.|:.||.:|:..:|.
Zfish   237 HDQILSKLLPKLKKHLDKEQMSSGIYSTKWFLQCFINRT-PFTLTLRLWDIFILEGEKVLTAMAY 300

  Fly   275 VIIGASLSRHKVRKTCTGLCETLAVLRSPEEHIVEEEFIINNMMRLNLRVEDFQIEHTRQKARRA 339
            .|    |..||.|.    |..:|..||...:..:.|...:|:    :|.:|  |::.:..:.|:.
Zfish   301 TI----LQLHKKRL----LKMSLEELREFLQEKIGESIYLND----DLVIE--QLKVSMSELRKM 351

  Fly   340 K 340
            |
Zfish   352 K 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wkd	NP_650089.1	RabGAP-TBC	114..277	CDD:366170	63/166 (38%)
si:ch211-288d18.1	XP_686696.2	TBC	98..311	CDD:214540	80/222 (36%)
si:ch211-288d18.1	XP_686696.2	DUF4688	<356..>444	CDD:292380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D976276at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920