Protein Alignment wkd and tbc1d25

DIOPT Version :9

• Sequence 1: NP_650089.1
• Gene: wkd / 41390
• FlyBaseID: FBgn0037917
• Length: 363
• Species: Drosophila melanogaster
• Sequence 2: NP_001121708.1
• Gene: tbc1d25 / 556338
• ZFINID: ZDB-GENE-041111-25
• Length: 863
• Species: Danio rerio
• Alignment Length: 376
• Identity: 79/376 - (21%)
• Similarity: 137/376 - (36%)
• Gaps: 90/376 - (23%)

  Fly    10 TISLCSTVSSCPDR-----NGFYGGFQRTDKPKEPLSKAQIIAREKKWLYMIDNWSIYMSKNY-- 67
            |.||.|.|.....|     :..||...:..||  |||.|:.                   .||
Zfish   139 TQSLLSQVGRTLSRVQQALSWSYGEEVKPFKP--PLSDAEF-------------------HNYLN 182

  Fly    68 --------KKIRDRC-RKGIPKSVRPKAWFYLSGAY-----------LLKKKNPNVYNELLEKPG 112
                    :::|.|. ..|:..|:|...|.||...|           .:|:|. ..|::|..:..
Zfish   183 SQGQLSRPEELRLRIYHGGVESSLRKVVWRYLLNVYPDGLTGQERMDYMKRKT-REYDQLKSEWT 246

  Fly   113 NPTTIEEIK-------KDKHRQFPFHEMFL-DEQKVGQIELFNVLKAYSIYNPKVGFCQAQAPIA 169
            ...:.||::       ||..|....|..:. .|.......|.::|..::|.:|:|.:||..:.||
Zfish   247 ARVSSEELEFIRGNVLKDVLRTDRAHPYYAGSEDSPHLTALTDLLTTFAITHPQVSYCQGMSDIA 311

  Fly   170 AFLLMHLPAEDAFWVFVSVCDVY--LQDYFIPGLEVIQNDAGILEGLLKKTCPPVYRHLQKHKVE 232
            :.:|..:  ::....|:..|.:.  |:..|.|..:::......|:.||:.:.|..|.:|.....:
Zfish   312 SPILAVM--DNEAHAFICFCGIMKRLEGNFRPDGQLMSIKFQHLKLLLQYSDPEFYSYLVSKGAD 374

  Fly   233 PLLYMTDWFLCAMTRTLPWETLLRVWDCFLAEGIRVIFKVALVIIGASLSRHKVRKTCTGLCETL 297
            .|.:...|.|..:.|...::..||:                |.:..:||...........|....
Zfish   375 DLFFCYRWLLLELKREFAFDDALRM----------------LEVTWSSLPPDPPETEVELLGPAF 423

  Fly   298 AVLRSPEEHIVEEEFIINNMMRLNLRVEDFQIEHTRQKARRAKQKAQQEAE 348
            ...:|...|.|:.|           .:|:.|.|  ||:.|...:.:::||:
Zfish   424 EADQSDGSHNVDME-----------EMEEKQTE--RQRRRHMLRPSREEAD 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wkd	NP_650089.1	RabGAP-TBC	114..277	CDD:366170	35/172 (20%)
tbc1d25	NP_001121708.1	TBC	198..420	CDD:214540	48/240 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810