Protein Alignment wkd and Tbc1d8

DIOPT Version :9

• Sequence 1: NP_650089.1
• Gene: wkd / 41390
• FlyBaseID: FBgn0037917
• Length: 363
• Species: Drosophila melanogaster
• Sequence 2: XP_017177250.1
• Gene: Tbc1d8 / 54610
• MGIID: 1927225
• Length: 1160
• Species: Mus musculus
• Alignment Length: 365
• Identity: 102/365 - (27%)
• Similarity: 155/365 - (42%)
• Gaps: 80/365 - (21%)

  Fly    30 FQR--TDKPKEPLSKAQIIAREKKWLYMIDNWSIYMSK--------NYKKIRDRCRKGIPKSVRP 84
            ||:  :..|...||:.||         .|..|:.:..:        ..:|||.....|||:|:|.
Mouse   471 FQQSGSQSPDSRLSREQI---------KISLWNDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRG 526

  Fly    85 KAWFYLSGAYLLKKKNPNVYNELLEKP-GNPTTI-EEIKKDKHRQFPFHEMFLDEQKVGQIELFN 147
            :.|...|.|......:|..|..|:|:. |....: |||::|.||..|.|..|.:|  .|...|..
Mouse   527 RLWLLFSDAVTDLASHPGYYGNLVEQSLGRCCLVTEEIERDLHRSLPEHPAFQNE--TGIAALRR 589

  Fly   148 VLKAYSIYNPKVGFCQAQAPIAAFLLMHLPAEDAFWVFVSVCDVYLQDYFIPGLEVIQNDAGILE 212
            ||.||:..|||:|:||:...:.:.||::...|:|||:.|:||:..|.|||...:...|.|..:.|
Mouse   590 VLTAYAHRNPKIGYCQSMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNHRVIGAQVDQSVFE 654

  Fly   213 GLLKKTCPPVYRHLQKHKVEPLLYMTDWFLCAMTRTLPWETLLRVWDCFLAEGIRVIFKVALVII 277
            .|:|:..|.:..|:........:.:: |||......:|.|:.:.|.|||..:||:.||::.|.::
Mouse   655 ELIKEQLPELAEHMSDLSALASISLS-WFLTLFLSIMPLESAVHVVDCFFYDGIKAIFQLGLAVL 718

  Fly   278 GASLSRHKVRKTCTGLC------ETLAVLRSPEEHIVEEEF------------------------ 312
            .|:...         ||      :.|.||....:||..|:.
Mouse   719 EANAEE---------LCSSKDDGQALMVLSRFLDHIKNEDSPGPPIGSHHAFFSDDQEPYPVTDI 774

  Fly   313 --IINNMMRL-------------NLRVEDFQIEHTRQKAR 337
              :|.:...|             |..||  ||||.|.|.|
Mouse   775 ADLIRDSYELWTQAVPVSMQKFGNQSVE--QIEHLRCKHR 812

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wkd	NP_650089.1	RabGAP-TBC	114..277	CDD:366170	56/163 (34%)
Tbc1d8	XP_017177250.1	PH-GRAM1_TBC1D8	171..269	CDD:270156
		PH-GRAM2_TBC1D8	311..406	CDD:270160
		TBC	519..725	CDD:214540	70/217 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R540
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840