Protein Alignment wkd and TBC1D3C

DIOPT Version :9

• Sequence 1: NP_650089.1
• Gene: wkd / 41390
• FlyBaseID: FBgn0037917
• Length: 363
• Species: Drosophila melanogaster
• Sequence 2: XP_006721967.1
• Gene: TBC1D3C / 414060
• HGNCID: 24889
• Length: 610
• Species: Homo sapiens
• Alignment Length: 383
• Identity: 103/383 - (26%)
• Similarity: 160/383 - (41%)
• Gaps: 76/383 - (19%)

  Fly     3 TAPRSLDTISLCSTVSSCPDRNGFYGGFQRTDKPKEPLSKAQI------IAREKKWLYMIDNWSI 61
            :|||.....:.||: |:.|       |...::....||:..:.      |:|:.||:.|:.:|..
Human    92 SAPRLGPLQAPCSS-SALP-------GLPYSETELPPLTAREAKQIRREISRKSKWVDMLGDWEK 148

  Fly    62 YMSKNYKKIRDRCRKGIPKSVRPKAWFYLSGAYLLKKKNPNVYNELLEKPGNPTT--IEEIKKDK 124
            |  |:.:|:.||..||:|.::|...|..|.....:|.|||..| :::::.|..::  |:.|.:|.
Human   149 Y--KSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRY-QIMKEKGKRSSEHIQRIDRDV 210

  Fly   125 HRQFPFHEMFLDEQKVGQIELFNVLKAYSIYNPKVGFCQAQAPIAAFLLMHLPAEDAFWVFVSVC 189
            ......|..|.|.....|.||.::|.||..|||:||:|:..:.|||..|::||.|||||..|.:.
Human   211 SGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLL 275

  Fly   190 DV---YLQDYFIPGLEVIQNDAGILEGLLKKTCPPVYRHLQKH----KVEPL----LYMTDWFLC 243
            ..   .||.:..|....:|......|.::..:.|....|..|.    :..||    ..:.|....
Human   276 ASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISL 340

  Fly   244 AMTRTLPWETLLRVWDCFLAEG-------IRVIFKVALVIIGASLSRHKVRKTCTGLCETLAVLR 301
            .:|        ||:||.:|.||       .|:.|||           .:.|.|.|..|...|
Human   341 GLT--------LRLWDVYLVEGEQALMPITRIAFKV-----------QQKRLTKTSRCGPWA--- 383

  Fly   302 SPEEHIVEEEFIINNMMRLNLRVEDFQIEHTRQKARRAKQK-------AQQEAESSGS 352
                      ...|..:....|.||..::|.|...::..:|       |:.|..||.|
Human   384 ----------RFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSAS 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wkd	NP_650089.1	RabGAP-TBC	114..277	CDD:366170	53/182 (29%)
TBC1D3C	XP_006721967.1	TBC	160..373	CDD:214540	65/232 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D976276at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820