Protein Alignment wkd and TBC1D26

DIOPT Version :9

• Sequence 1: NP_650089.1
• Gene: wkd / 41390
• FlyBaseID: FBgn0037917
• Length: 363
• Species: Drosophila melanogaster
• Sequence 2: NP_001375394.1
• Gene: TBC1D26 / 353149
• HGNCID: 28745
• Length: 468
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 81/250 - (32%)
• Similarity: 116/250 - (46%)
• Gaps: 33/250 - (13%)

  Fly    48 REKKWLYMIDNWSIYMSKNYKKIRDRCRKGIPKSVRPKAWFYLSGAYLLKKKNPNVYNELLEKPG 112
            |..||..|:.:|:.|.|.  ||:..|..|.||.:||.:||..|.....:|.:||..|..:.||..
Human    74 RTNKWQKMLADWTKYRST--KKLSQRVYKVIPLAVRGRAWSLLLDIDRIKSQNPGKYKVMKEKGK 136

  Fly   113 NPTTIEE-IKKDKHRQFPFHEMFLDEQKVGQIELFNVLKAYSIYNPKVGFCQAQAPIAAFLLMHL 176
            ..:.|.. |:.|.......|.||:....|.|.||.::|.|||.|||:||:.:..:.|.|.||:.|
Human   137 RSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNPEVGYHRDLSRITAILLLCL 201

  Fly   177 PAEDAFWVFVSVCDVYLQDYFIPGLEVIQNDAGILEGLLKKTCPPVYRHLQKHKVEPLLYMTDWF 241
            |.|||||....:..|    ::.|....::......|.:|.|:.|.:.|||.|..
Human   202 PEEDAFWALTQLLAV----FYSPNTAWLERLLSHQEQVLHKSFPKIMRHLGKEG----------- 251

  Fly   242 LC----AMTRTL-------PWETLLRVWDCFLAEGIRVIFKVALVIIGASLSRHK 285
            ||    .:||.|       .:...||:||.|:.||.||:    ..::.||...|:
Human   252 LCIEGSMLTRLLRCFLDGKSFGLTLRLWDVFILEGARVL----TAMVHASFKIHR 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wkd	NP_650089.1	RabGAP-TBC	114..277	CDD:366170	54/174 (31%)
TBC1D26	NP_001375394.1	TBC	98..306	CDD:214540	71/223 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D976276at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820