Protein Alignment wkd and Tbc1d8b

DIOPT Version :10

• Sequence 1: NP_650089.1
• Gene: wkd / 41390
• FlyBaseID: FBgn0037917
• Length: 363
• Species: Drosophila melanogaster
• Sequence 2: NP_001388066.1
• Gene: Tbc1d8b / 315912
• RGDID: 1563084
• Length: 1118
• Species: Rattus norvegicus
• Alignment Length: 299
• Identity: 87/299 - (29%)
• Similarity: 141/299 - (47%)
• Gaps: 42/299 - (14%)

  Fly    58 NWSIYMSK--------NYKKIRDRCRKGIPKSVRPKAWFYLSGAYLLKKKNPNVYNELLEKPGNP 114
            :|:|..|:        ..||.||...:|||:::|.:.|...|||......||..|.|::|:....
  Rat   459 SWNILFSECGRGVSMFRTKKTRDLVVRGIPETLRGELWMLFSGAVNDMAANPGYYAEVVEQSLGT 523

  Fly   115 TTI--EEIKKDKHRQFPFHEMFLDEQKVGQIELFNVLKAYSIYNPKVGFCQAQAPIAAFLLMHLP 177
            :.:  |||::|..|..|.|..|  :...|...|..||.||:..|||:|:|||...:.:.||::..
  Rat   524 SNLATEEIERDLRRSLPEHPAF--QSDTGISALRRVLTAYAYRNPKIGYCQAMNILTSVLLLYAK 586

  Fly   178 AEDAFWVFVSVCDVYLQDYF---IPGLEVIQNDAGILEGLLKKTCPPVYRHLQKHKVEPLLYMTD 239
            .|:|||:.|:||:..|.|||   |.|..|   |..:.|.|::...|.:..|           |||
  Rat   587 EEEAFWLLVAVCERMLPDYFNRRIIGALV---DQAVFEELIRDHLPQLTDH-----------MTD 637

  Fly   240 ----------WFLCAMTRTLPWETLLRVWDCFLAEGIRVIFKVALVIIGASLSRHKVRKTCTGLC 294
                      |||......||.|:.:.|.|||..:||:.|.::.|.|:..:|.:   ..||....
  Rat   638 MTFFSSVSLSWFLTLFISVLPIESAVNVVDCFFYDGIKAILQLGLAILDYNLDK---LLTCKDDA 699

  Fly   295 ETLAVLRSPEEHIVEEEFIINNMMRLNLRVEDFQIEHTR 333
            |.:..|....::::.::..:.:.::....:.|.:..|.:
  Rat   700 EAVTALNRFFDNVINKDSPLPSNVQQGSNINDGKSNHAK 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wkd	NP_650089.1	TBC	74..278	CDD:214540	73/218 (33%)
Tbc1d8b	NP_001388066.1	PH-GRAM1_TBC1D8B	156..254	CDD:275419
		PH-GRAM2_TBC1D8B	296..388	CDD:270159
		TBC	485..693	CDD:214540	74/226 (33%)