DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wkd and gyp51

DIOPT Version :9

Sequence 1:	NP_650089.1	Gene:	wkd / 41390	FlyBaseID:	FBgn0037917	Length:	363	Species:	Drosophila melanogaster
Sequence 2:	NP_594886.1	Gene:	gyp51 / 2542680	PomBaseID:	SPAC26F1.09	Length:	1031	Species:	Schizosaccharomyces pombe

Alignment Length:	189	Identity:	49/189 - (25%)
Similarity:	83/189 - (43%)	Gaps:	14/189 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 YNELLEKPGNPTTIEEIKKDKHRQFP---FHEMFLDEQKV--------GQIELFNVLKAYSIYNP 157
            |:.|..|  |..:.:.|:||..|.|.   ....|.:.|::        ....|..||::.:|..|
pombe   635 YSSLSIK--NCDSDKAIRKDLDRTFAPEILSHFFSNRQQLEPTDNIAESTANLHRVLRSLAIVLP 697

  Fly   158 KVGFCQAQAPIAAFLLMHLPAEDAFWVFVSVCDVY-LQDYFIPGLEVIQNDAGILEGLLKKTCPP 221
            :||:.|..:.||..|||||||..||.:.|.:...| ||:.|...:..:.........|::...|.
pombe   698 QVGYTQGMSWIAGALLMHLPAPQAFALLVFLFKNYHLQNIFSSEMRGLSRVLHQFTRLVEDYMPS 762

  Fly   222 VYRHLQKHKVEPLLYMTDWFLCAMTRTLPWETLLRVWDCFLAEGIRVIFKVALVIIGAS 280
            :..|.::..::...|.::|||.......|.|.:..::|.....|..::|...|.::..|
pombe   763 LAIHFKRQDIKTCSYASEWFLTLFAYKFPLEVVAHLYDILFLYGPGILFNFGLALLSHS 821

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wkd	NP_650089.1	RabGAP-TBC	114..277	CDD:366170	44/174 (25%)
gyp51	NP_594886.1	COG5210	233..890	CDD:227535	49/189 (26%)
		TBC	569..826	CDD:214540	49/189 (26%)
		PspA	889..>1024	CDD:224755
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810