Protein Alignment wkd and tbc-12

DIOPT Version :9

• Sequence 1: NP_650089.1
• Gene: wkd / 41390
• FlyBaseID: FBgn0037917
• Length: 363
• Species: Drosophila melanogaster
• Sequence 2: NP_508458.1
• Gene: tbc-12 / 180556
• WormBaseID: WBGene00044061
• Length: 614
• Species: Caenorhabditis elegans
• Alignment Length: 364
• Identity: 88/364 - (24%)
• Similarity: 150/364 - (41%)
• Gaps: 68/364 - (18%)

  Fly    31 QRTDKPK------EPLSKAQIIAREKKWL-YMIDNWSIYMSKNYKKIRDRCRKGIPKSVRPKAWF 88
            ||.:|.:      :...:.|..|..:.|: .::..|.  ..|:.|:.|:...:|:|..||.:.||
 Worm   247 QRAEKERLQAKAEQKRLEEQTAAHCRVWVEQILPKWE--EMKDSKRCRELWWQGVPAKVRGELWF 309

  Fly    89 YLSGAY----------LLKKKNPNVYNELLEKPGN-----PTTIEEIKKDKHRQFPFHEMFLDEQ 138
            ...|..          |:.:....:..:|.|:..|     .|::.:|..|..|.|....||   |
 Worm   310 LTIGNQIEITKELYDGLMDQAEEKIAKQLAEQNKNSAERKETSVTQIHLDATRTFTSLGMF---Q 371

  Fly   139 KVGQI--ELFNVLKAYSIYNPKVGFCQAQAPIAAFLLMHLPAEDAFWVFVSVCDVYLQDYFIPGL 201
            |.|..  .|..:|.||:|..|.:|:.|:...|||.||:.:....||..|.::.|..||..|. ||
 Worm   372 KDGPYYDHLLKLLSAYAILRPDIGYVQSMTFIAAVLLIQMDPYPAFISFANLLDRSLQSAFF-GL 435

  Fly   202 EVIQNDAGIL--EGLLKKTCPPVYRHLQKHKVEPLLYMTDWFLCAMTRTLPWETLLRVWDCFLAE 264
            :..|.....:  :..|::..|.:::||.|..|.|.||:.:|......::||.:...|:||.:..:
 Worm   436 KQPQMTEYFIAYDRYLEQELPALHQHLDKLDVRPDLYLIEWTFAMYAKSLPLDVTCRIWDVYFRD 500

  Fly   265 GIRVIFKVALVIIGASLSRHKVRKTCTGLCETLAVLRSPEEHIVEEEF---------IINNMMRL 320
            |...:||.|                       |.:||..|..::..:|         :.|.:...
 Worm   501 GEEFLFKAA-----------------------LGILRMYEPKLLTMDFDDCVEFLTKLPNTLTGA 542

  Fly   321 NL--RVEDFQIEHTRQKARRAKQKAQ--QEAESSGSGNG 355
            .|  .:|.|...:..:.:|..|:.:|  ||.:...:..|
 Worm   543 ELFRNIEPFMRPYNGESSRSKKRFSQIFQEIDERVNPGG 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wkd	NP_650089.1	RabGAP-TBC	114..277	CDD:366170	52/166 (31%)
tbc-12	NP_508458.1	TBC	295..521	CDD:214540	67/252 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810