Protein Alignment wkd and tbc-9

DIOPT Version :9

• Sequence 1: NP_650089.1
• Gene: wkd / 41390
• FlyBaseID: FBgn0037917
• Length: 363
• Species: Drosophila melanogaster
• Sequence 2: NP_502598.2
• Gene: tbc-9 / 178316
• WormBaseID: WBGene00012868
• Length: 1247
• Species: Caenorhabditis elegans
• Alignment Length: 327
• Identity: 89/327 - (27%)
• Similarity: 147/327 - (44%)
• Gaps: 53/327 - (16%)

  Fly     7 SLDTISLCSTVSSCPDRNGFYGGFQRTDKPKEPLSKAQIIAREKKWLYMIDNWSIYMSK------ 65
            |..:.|....:..||....:..|...:||           .|||        |:.|:.:
 Worm   430 SSSSSSFDKLIWDCPLIEKYPFGADASDK-----------CREK--------WNKYLQEYGTGVC 475

  Fly    66 NYK--KIRDRCRKGIPKSVRPKAWFYLSGAYLLKKKNPNVYNELLEKPGN--PTTIEEIKKDKHR 126
            .|:  ::.....:|:|..:|.:.|...|||......||..|.|||.|...  ...:|||::|.||
 Worm   476 MYRTVELHRLLLEGVPLQLRGQIWMVCSGAAAEMALNPGYYRELLHKNQGVYSVALEEIERDLHR 540

  Fly   127 QFPFHEMFLDEQKVGQIELFNVLKAYSIYNPKVGFCQAQAPIAAFLLMHLPAEDAFWVFVSVCDV 191
            ..|.|..|  :|..|...|..:|.||:..||.:|:|||...:.:.||:....|:|||:.|:||:.
 Worm   541 SLPEHPAF--QQGPGIDALRRILTAYAFRNPNIGYCQAMNIVGSVLLLFTKEEEAFWLLVAVCER 603

  Fly   192 YLQDYF---IPGLEVIQNDAGILEGLLKKTCPPVYRHLQKHKVEPLLYMTDWFLCAMTRTLPWET 253
            .|.||:   :.|..|   |.|:...|:::..|.|...|.:..::.::.:: |||......:.::.
 Worm   604 LLPDYYNTKVVGALV---DQGVFSELVERLLPTVGAQLTRLGLDDMVALS-WFLTVFLSAIKFDA 664

  Fly   254 LLRVWDCFLAEGIRVIFKVALVIIGASLSRHKVRKTCTGLCET------LAVLRSPEEHIVEEEF 312
            .:|:.|.|..||.|::|:|||.::   ....|:      :||:      |..|....|.|.|.:.
 Worm   665 AVRILDLFFFEGARLMFQVALEML---KENEKL------ICESRDDGEILMSLAKYTESIYEGDT 720

  Fly   313 II 314
            ::
 Worm   721 VV 722

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wkd	NP_650089.1	RabGAP-TBC	114..277	CDD:366170	54/165 (33%)
tbc-9	NP_502598.2	PH-GRAM1_TCB1D9_TCB1D9B	154..253	CDD:275420
		PH-GRAM2_TCB1D9_TCB1D9B	309..406	CDD:270161
		TBC	489..695	CDD:214540	69/220 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R540
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940