Protein Alignment wkd and TBC1D21

DIOPT Version :9

• Sequence 1: NP_650089.1
• Gene: wkd / 41390
• FlyBaseID: FBgn0037917
• Length: 363
• Species: Drosophila melanogaster
• Sequence 2: XP_006720472.1
• Gene: TBC1D21 / 161514
• HGNCID: 28536
• Length: 399
• Species: Homo sapiens
• Alignment Length: 328
• Identity: 61/328 - (18%)
• Similarity: 111/328 - (33%)
• Gaps: 97/328 - (29%)

  Fly    35 KPKEPLSKAQIIAREKKWLYMIDNWSIYMSKNYKKIRD-RC----RKGIPKSVRPKAWFYLSGAY 94
            |.|.|:.|.:       |....|.     |.:..|.|| .|    .:|:...||.:||.:|:|.:
Human    22 KRKPPIDKTE-------WDSFFDE-----SGHLAKSRDFICVNILERGLHPFVRTEAWKFLTGYF 74

  Fly    95 -------------LLKKKNPNVYNELLEKPGNPTTIEEIKKDKHRQF------------------ 128
                         .:::||.....::.||      |:.:.::.||.|
Human    75 SWQSSQDERLTVDSMRRKNYKALCQMYEK------IQPLLENLHRNFTETRNNIARDIQKIYDKD 133

  Fly   129 PFHEMFLDEQKVGQIELFNVLKAYSIYNPKVGFCQAQAP--------IAAFLLMHLPAEDAFWVF 185
            |...:.:|::::.:|.|.:.:            |..||.        :..|.||.....:.||:|
Human   134 PLGNVLIDKKRLEKILLLSYV------------CNTQAEYQQGFHEMMMLFQLMVEHDHETFWLF 186

  Fly   186 VSVCDVYLQDYFIPGLE-------VIQNDAGILEGLLKKTCPPVYRHLQKHKVEPLLYMTDWF-L 242
                     .:|:...|       .:..:..:|..|:....|....||:......:..:..|| .
Human   187 ---------QFFLQKTEHSCVINIGVAKNLDMLSTLITFLDPVFAEHLKGKGAGAVQSLFPWFCF 242

  Fly   243 CAMTRTLPWETLLRVWDCFLAEGIRVIFKVALVIIGASLSRHKVRKTCTG------LCETLAVLR 301
            |.......::.:.|:|:..|.......|:|.:......:.|.:|.:...|      .|..|..|.
Human   243 CFQRAFKSFDDVWRLWEVLLTGKPCRNFQVLVAYSMLQMVREQVLQESMGGDDILLACNNLIDLD 307

  Fly   302 SPE 304
            :.|
Human   308 ADE 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wkd	NP_650089.1	RabGAP-TBC	114..277	CDD:366170	32/196 (16%)
TBC1D21	XP_006720472.1	TBC	62..287	CDD:214540	43/251 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810