DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wkd and usp6nl

DIOPT Version :9

Sequence 1:	NP_650089.1	Gene:	wkd / 41390	FlyBaseID:	FBgn0037917	Length:	363	Species:	Drosophila melanogaster
Sequence 2:	XP_031754908.1	Gene:	usp6nl / 100135167	XenbaseID:	XB-GENE-998647	Length:	844	Species:	Xenopus tropicalis

Alignment Length:	331	Identity:	101/331 - (30%)
Similarity:	163/331 - (49%)	Gaps:	35/331 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 DRNGFYGGFQRTDKP--KEPLSKAQI--IAREKKWLYMIDNWSIYMSKNYKKIRDRCRKGIPKSV 82
            ||.||   ..:.:.|  .|...|.::  |.|..||:.||.:|..|  ||.:|:..|..||||..:
Frog    71 DRFGF---LHKEELPIHDEVAQKQKLLEIERTTKWVKMIKSWDKY--KNSEKLHRRIYKGIPLQL 130

  Fly    83 RPKAWFYLSGAYLLKKKNPNVYNELLEKPGN-PTTIEEIKKDKHRQFPFHEMFLDEQKVGQIELF 146
            |.:.|..:.....||::..::|..|.:|... ...|.:|..|.:|.|..|.||.:...|.|..||
Frog   131 RGEVWSLILEVSKLKEERKDLYLVLKQKARRLSADIRQIDLDVNRTFRDHIMFRERYGVKQQALF 195

  Fly   147 NVLKAYSIYNPKVGFCQAQAPIAAFLLMHLPAEDAFWVFVSVCD---VYLQDYFIPGLEVIQNDA 208
            :||.|||:||.:||:||..:.|.|.|||::..|||||..|.:..   ..:..:|:||...:....
Frog   196 HVLAAYSLYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVPGFPKLLRFQ 260

  Fly   209 GILEGLLKKTCPPVYRHLQKHKVEPLLYMTDWFL-CAMTRTLPWETLLRVWDCFLAEGIRVIFKV 272
            ...:.:|||..|.:.:|.:..::...||...||. |.:.|| |:...||:||.::.||.|::..:
Frog   261 EHHDRILKKFMPKLKQHFETQELYTSLYTMKWFFQCFLDRT-PFTLNLRIWDIYILEGERILTAM 324

  Fly   273 ALVIIGASLSRHK---VRKTCTGLCETLAVLRSPEEHIVEEEFIINNMMRLNLRVEDFQIEHTRQ 334
            :..|    |..||   ::::...|.|.|....:.:.| .:::::|:            |:..:..
Frog   325 SYAI----LKLHKRTLIKQSLEDLIEFLQEELARDFH-YDDDYVID------------QLSLSMT 372

  Fly   335 KARRAK 340
            :.||||
Frog   373 ELRRAK 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wkd	NP_650089.1	RabGAP-TBC	114..277	CDD:366170	57/166 (34%)
usp6nl	XP_031754908.1	TBC	122..337	CDD:214540	72/219 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D976276at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920