Protein Alignment CG5342 and GPI13

DIOPT Version :10

• Sequence 1: NP_650088.2
• Gene: CG5342 / 41389
• FlyBaseID: FBgn0037916
• Length: 837
• Species: Drosophila melanogaster
• Sequence 2: NP_013069.1
• Gene: GPI13 / 850628
• SGDID: S000003954
• Length: 1017
• Species: Saccharomyces cerevisiae
• Alignment Length: 941
• Identity: 178/941 - (18%)
• Similarity: 307/941 - (32%)
• Gaps: 335/941 - (35%)

  Fly    13 LLLLFAVVLIYLRSTY--PGSLEPQEV--------EHLKEPPPADRLVVLVRDGLSAQSFLANRC 67
            :||:|..:|.::...:  .|.|..:.|        |..|.||..::.|:||.|.|...
Yeast    37 ILLVFIAILQFISIAFFTRGFLLSRHVLDNISSQNETSKLPPRFNKAVILVIDALRFD------- 94

  Fly    68 TNVPLLRELFLHQGLVGISRPETITYHSISPYISLFSGF--NEDAASVARGWLGTPASIDSIFDR 130
            ..:|:...   |...       .:.||  :..:||:..|  ::||:|:...::..|.
Yeast    95 FAIPVNES---HSNY-------NLNYH--NNILSLYDSFASDKDASSLLLKFIADPP-------- 139

  Fly   131 CKRSFAWTTTELISRFPKIERPRELSFETYGEGVTKSCSEMEDF-----VCRSVQRFLGGGSRLL 190
                   |||  :.|...:......:|...|.....:..|.::|     :.....:|.|.
Yeast   140 -------TTT--LQRLKGLTTGSLPTFIDAGSNFDGTVIEEDNFLKQLHLANKTVKFAGD----- 190

  Fly   191 LNTTGVIFFIHMTGVEPSCESLQRIQENVWN-------VYKSF-EKTFPDQRTAYLFTSNLG--- 244
             :|...:|...::......|||     |||:       |...| :....|:....:....||
Yeast   191 -DTWMALFHPFLSNDSFPLESL-----NVWDLDTVDNGVMDYFHDHLQQDKEWDVMIGHMLGIDH 249

  Fly   245 -------DPQTKSEYSLAVESPFFLW---------------GSGVNHIKSMPGRSFMANEAGLRL 287
                   |..|..|..:.|:. |..|               ..|::|..:..|.|....|:.|.|
Yeast   250 VGHKYGPDHFTMREKQIQVDQ-FIDWILKSIDDDTLLVILGDHGMDHTGNHGGDSIDELESTLFL 313

  Fly   288 --------------PLHVLNTPH---------LTALMSALLGVPPPVYSRGMLP----------- 318
                          ..::.|..|         |.:.::.|:|.|.|..:.|. |
Yeast   314 YSKKPDMWRLKETSNYNIDNLGHDYRSVRQIDLVSSLALLMGQPIPFNNLGW-PIDEIARNDREW 377

  Fly   319 KGMLNAS---LRYEANAMLI---NAKQLLAQARRLRELHPKRMPAFWLSFQMMDNFVKESLALKK 377
            ...:|::   |:...:.|.|   |.:.|...|:.:....|...|         :.|||  |..|.
Yeast   378 SQFVNSAISQLQLYKDTMQIHHGNDEILEPLAKNISNTPPTSDP---------EKFVK--LGHKY 431

  Fly   378 QRRFRALLDYSCNYMPVLIKGMDYFK-DYYRHVSI-TAVSFAGIAWIYCLRCHLTVGKKCRNLIE 440
            |:.|.    .:|..:        :.| |||   || |.::....:.:.              ||.
Yeast   432 QKVFL----QTCEEL--------WAKFDYY---SIATGITLLATSLVL--------------LIS 467

  Fly   441 IQEVISSKRLVYARGFHRLLTGVLVIIMMLERIPLVVQAILLI---PSL---YWRTTLKILGERP 499
            |.::|.|  :|..:.....:.|:::::::..   |....|..:   ||.   :|.|
Yeast   468 ITKLIPS--IVVNQMVPEFVPGIIIMVLVTN---LCFHGIFYVYQQPSFVDQFWGT--------- 518

  Fly   500 KMVCRKSLMSTALLALI-CFGGFFRRYILAVGYLGFASYNNREAFKRRGHQFYLWLLLLLGLTVV 563
                   |::||:..:| |:...|.||                        .::|:.:.||.|:.
Yeast   519 -------LLATAIGIIIGCYITIFDRY------------------------NFIWIAMRLGETLA 552

  Fly   564 SALPESLGCSQPGALMFSIFLTVLRPLACGVYLNLLTWLSNIPVLLAALEYILIGWHPWIMYLVS 628
            ......       |:||.|             ::.|.:.||
Yeast   553 DYWSRI-------AVMFMI-------------IHALLFTSN------------------------ 573

  Fly   629 WIYLGFLVLWQRRNLQASEVFFFDLSTLYTLTCTSYESVVI---QMLAMELQLALRMKLKRNESI 690
                 ...:|:.|      :..|.|||...||.  ||.|.:   |.....|...:..|......:
Yeast   574 -----SFTIWEDR------IVAFLLSTFGMLTL--YEFVFLPKRQSTTALLTATISEKEGTTSGV 625

  Fly   691 GPKTA-AHYI-------LVYSWYSLFIIGSFPAFDDFLDILHETCFGYSPLTY-----------G 736
            .|.|| ::|:       |:..::|..:| .|......:.|..|....|...|:           |
Yeast   626 NPSTANSNYLPLTRFARLLGGYHSAVLI-IFTRLASMITICREEQGEYCIPTFNNQNNSSWWVLG 689

  Fly   737 LVMVLKLILPWLLVLCIMAGNYKSLASYEQ------QIFVR-LLLMN----SAMSLVLLHGITNV 790
            |..::..|||    .|| .|.|...:||:.      .:|:: :|.:|    |..||.....:..:
Yeast   690 LCFLMIFILP----ACI-TGYYNLTSSYQAAAPIWINVFLKGILGLNFVYWSLTSLENNSAVIAI 749

  Fly   791 GPWRDI-LSRFAEFAVVHVFPLV-----WLL 815
            ...||: :.:|....::..|.|:     ||:
Yeast   750 PFLRDVTIFKFTLARIIAGFSLIASNVGWLM 780

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5342	NP_650088.2	GPI_EPT_1	43..318	CDD:293744	62/337 (18%)
		PigN	397..781	CDD:461508	80/425 (19%)
GPI13	NP_013069.1	GPI_EPT_3	77..367	CDD:293747	62/338 (18%)