Protein Alignment CG5342 and ENPP2

DIOPT Version :10

• Sequence 1: NP_650088.2
• Gene: CG5342 / 41389
• FlyBaseID: FBgn0037916
• Length: 837
• Species: Drosophila melanogaster
• Sequence 2: XP_006716647.1
• Gene: ENPP2 / 5168
• HGNCID: 3357
• Length: 940
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 66/298 - (22%)
• Similarity: 104/298 - (34%)
• Gaps: 91/298 - (30%)

  Fly    87 RPETITYHSISPYISLFSG-----FNEDAASVARGWLGTPASIDSIFDRCKRSFAWTTTELISRF 146
            ||....::|..|.   |||     |..:.:|....:  |||.      |.||..|....:.....
Human   300 RPSVYAFYSEQPD---FSGHKYGPFGPEESSYGSPF--TPAK------RPKRKVAPKRRQERPVA 353

  Fly   147 P------KIERPRELSFETYGEGVTKSCSEMEDFVCRSVQRFLGGGSRLLLNTTGVIFFIHMTGV 205
            |      ||.|....:.||..:.:|....|::    :.|.:.:.|..:|.|:....:.|:...|:
Human   354 PPKKRRRKIHRMDHYAAETRQDKMTNPLREID----KIVGQLMDGLKQLKLHRCVNVIFVGDHGM 414

  Fly   206 EP-SCESLQRIQENVWNVYKSFEKTFPDQRTAYLFTSNLGDPQTKSEYSLAVESPFFLWGSGVNH 269
            |. :|:..:.:...:.||         |..|  |....||  :.:|::|              |:
Human   415 EDVTCDRTEFLSNYLTNV---------DDIT--LVPGTLG--RIRSKFS--------------NN 452

  Fly   270 IKSMPGRSFMANEAGLRLPLHVLNTPHLTALMSALLGVPPPVYSRGMLPKGMLNASLRYEANAML 334
            .|..| ::.:||....:...|.  .|:|                :..|||     .|.| ||...
Human   453 AKYDP-KAIIANLTCKKPDQHF--KPYL----------------KQHLPK-----RLHY-ANNRR 492

  Fly   335 INAKQLLAQARRLRELHPKRMPAFWLSFQMMDNFVKES 372
            |....||.:    |..|..|.|        :|.:.|.|
Human   493 IEDIHLLVE----RRWHVARKP--------LDVYKKPS 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5342	NP_650088.2	GPI_EPT_1	43..318	CDD:293744	49/242 (20%)
		PigN	397..781	CDD:461508
ENPP2	XP_006716647.1	SO	55..98	CDD:197571
		SO	99..142	CDD:197571
		Phosphodiest	166..530	CDD:396300	66/298 (22%)
		AslA	<330..>413	CDD:442353	20/94 (21%)
		NUC	692..922	CDD:214683