Protein Alignment CG6790 and MCD4

DIOPT Version :10

• Sequence 1: NP_650087.2
• Gene: CG6790 / 41388
• FlyBaseID: FBgn0037915
• Length: 897
• Species: Drosophila melanogaster
• Sequence 2: NP_012756.1
• Gene: MCD4 / 853690
• SGDID: S000001648
• Length: 919
• Species: Saccharomyces cerevisiae
• Alignment Length: 981
• Identity: 212/981 - (21%)
• Similarity: 382/981 - (38%)
• Gaps: 243/981 - (24%)

  Fly    48 VLVHLLLLICIMRIFYQSGPLSQLEPQKTLLDMGVP-PAADRLVVFLLEGLRADTLF---SDNCS 108
            ||.||..|..|..|::.|..:..:.|.::     .| |.|.||.:.:.:||||||.|   :...|
Yeast    14 VLFHLFYLWSIFDIYFISPLVHGMSPYQS-----TPTPPAKRLFLIVGDGLRADTTFDKVTHPVS 73

  Fly   109 G-----AVYIRDIILRQGLVGISKTSVPTLTRSAEVALFAGF-------------NPMPSILPTS 155
            |     |.:||.:::.....|||.|.:||.:|...||:.|||             ||:
Yeast    74 GKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVSAVTKGWKSNPV------- 131

  Fly   156 NFDTIFNR---TLAF------------------------------------DKGAFLRFSHLSDL 181
            |||:.||:   |.:|                                    :..||: |.||..|
Yeast   132 NFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDFTQSSIELDAFV-FRHLDQL 195

  Fly   182 RRRLTKRACLEKLWYANKLVMLVNLAEVGGASPLDIGFQMKLHNTQRNIRDAYEL----IEATFN 242
            ....|..:.|:.....:..|..::|.....|......:..:.::..:.|.|...:    :...|.
Yeast   196 FHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYIDDQIPILIDKVNKFFA 260

  Fly   243 DSKTAYLYTSAHGLTYFGSHGGGSDEEREAPFLLWGAGVKH-------VTENITSDFVLNNGVGM 300
            |.|||:::|:.||::.|||||.|.......|.:.||||:..       |::|.|.::.|::   :
Yeast   261 DDKTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLNKPVHNPFPVSDNYTENWELSS---I 322

  Fly   301 QLHKLDQIQLAPLMSALIGLPPPVNNLAILPQGYMKVSREYARKSVHLNALQLLTQ--------- 356
            :.:.:.|..:|.|||.|||:..|.|::..||..|:.........:::.||..:|.|
Yeast   323 KRNDVKQADIASLMSYLIGVNYPKNSVGELPIAYIDGKESDKLAALYNNARSILEQYLVKQDEVI 387

  Fly   357 -----AKAIIRLHERGVFHKWLPKDKDLDLQQIAYYQNQMDHLLDMGWRSKALETSTLAIKVALK 416
                 .|...:..|:...| :|.:.:.| :|:|:..:|.::        .:|:..:...:::.|:
Yeast   388 DSQFFYKEYFKFVEKSHSH-YLEEIETL-IQRISEGENYLE--------QEAITLTEELMQITLE 442

  Fly   417 SLKFY--HNYYHIPLVVTTVLALLGWQFYQLV-----KLSQNVM-----AP--HYMRRGYLTWCT 467
            .|.:.  :|:..|..:||  ...:||.|:..:     .:.:||:     :|  |          .
Yeast   443 GLHYLTTYNWRFIRTIVT--FGFVGWIFFSFIIFLKSFILENVIDDQKASPLSH----------A 495

  Fly   468 IFLASLGLLLGEMVFLQWAPFMTVICLVVPFGVWCMTLAALPQNGGWIFEPLKHLR--------- 523
            :| .|:|:||..::|.|.:||...:.|:.|...|           .:||.....||
Yeast   496 VF-GSIGILLNWILFYQHSPFNFYMYLLFPLYFW-----------SYIFTNRSVLRSGIKEFFKG 548

  Fly   524 ---WIVGPAAVMIASIYCNCPLSLAYILCVGFYNRRGW----------LHP--------SPKFLA 567
               |......:.|.|:|    ..:.|    ||::|  |          .:|        |...|
Yeast   549 TSPWKRVLITISIISVY----EGIVY----GFFHR--WTFTLITNILAFYPFICGVRELSVNIL- 602

  Fly   568 WLALVLLLGGFLWSQ------------KGMQILMTTNYRV---------VLQAISMLVVIVRPCV 611
            |:...:||..|....            .|:.|:::..|.:         ..:||..:.:.:...:
Yeast   603 WIITSVLLSTFTLFDAVKIEDLNQIHLAGLLIILSAFYALYKIHSRINSYTRAIFAIQISLVAAM 667

  Fly   612 LNENHKWKVWVINGGILFVAAIGIFLKEMGKPVPLYLFAANWAYLIYAFASVPCSSRTTPQS--- 673
            |...|:             :.|.:.|::   .:|.....|.|.....:...:|......|.:
Yeast   668 LAVTHR-------------SVISLQLRQ---GLPRESQVAGWIIFFVSLFVMPILHYRKPNNDYK 716

  Fly   674 -RLELIRFNLLTLHVLLSDSYVSLFAQGLIIEYQM-GLEVHEKFKEADEDVKILTSSKHLQMCYR 736
             ||.:|........::|:.|:.||| ..|...|.: .:|:..|.||    :|.......||:
Yeast   717 VRLLIIYLTFAPSFIILTISFESLF-YFLFTSYMVQWIEIENKIKE----MKTQKDENWLQV--- 773

  Fly   737 FAVSILLYF--YASLFGTGHWVGGFTYLANSARLFLPDSSSGLVPLLVLIHLLIPSIVIMASVVA 799
            ..||::.:|  ..:.||||:.....::...|....||.....|:..|:::.|:||..::...:..
Yeast   774 LRVSVIGFFLLQVAFFGTGNVASISSFSLESVCRLLPIFDPFLMGALLMLKLIIPYGLLSTCLGI 838

  Fly   800 LSSFGRQQIRTIFSSLMLICNAVVLFFVVFVPHNAYWPMAHPSVVHALLAQLTVILILACESIVT 864
            |:.....:..||.|.::.:.:.:.|.|...:.....|.....::.:..||.|:.:.:|..|.:..
Yeast   839 LNLKLNFKDYTISSLIISMSDILSLNFFYLLRTEGSWLDIGITISNYCLAILSSLFMLILEVLGH 903

  Fly   865 IFFRRL 870
            :..:.:
Yeast   904 VLLKNV 909

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6790	NP_650087.2	GPI_EPT_1	83..331	CDD:293744	84/319 (26%)
		PigN	418..821	CDD:461508	94/474 (20%)
MCD4	NP_012756.1	GPI_EPT_1	46..353	CDD:293744	83/317 (26%)
		PigN	442..874	CDD:461508	96/490 (20%)