Protein Alignment CG6790 and GPI13

DIOPT Version :10

• Sequence 1: NP_650087.2
• Gene: CG6790 / 41388
• FlyBaseID: FBgn0037915
• Length: 897
• Species: Drosophila melanogaster
• Sequence 2: NP_013069.1
• Gene: GPI13 / 850628
• SGDID: S000003954
• Length: 1017
• Species: Saccharomyces cerevisiae
• Alignment Length: 1087
• Identity: 198/1087 - (18%)
• Similarity: 359/1087 - (33%)
• Gaps: 394/1087 - (36%)

  Fly    47 VVLVHLLLLICIMRIFYQSGPL----------SQLEPQKTLLDMGVPPAADRLVVFLLEGLRADT 101
            ::||.:.:|..|...|:..|.|          ||.|..|      :||..::.|:.:::.||.|.
Yeast    37 ILLVFIAILQFISIAFFTRGFLLSRHVLDNISSQNETSK------LPPRFNKAVILVIDALRFDF 95

  Fly   102 LFSDNCSGAVY--------------------IRDIILR----------QGLVGISKTSVPTLTRS 136
            ....|.|.:.|                    ...::|:          |.|.|::..|:||.
Yeast    96 AIPVNESHSNYNLNYHNNILSLYDSFASDKDASSLLLKFIADPPTTTLQRLKGLTTGSLPTF--- 157

  Fly   137 AEVALFAGFNPMPSILPTSNFD-TIFNRTLAFDKGAFLRFSHLSDLRRRLTKRACLEKLWYA--- 197
                :.||          |||| |:      .::..||:..||::    .|.:...:..|.|
Yeast   158 ----IDAG----------SNFDGTV------IEEDNFLKQLHLAN----KTVKFAGDDTWMALFH 198

  Fly   198 ----NKLVMLVNLAEVGGASPLDIGFQMKLHNTQRNIR---------------------DAYELI 237
                |....|.:| .|.....:|.|.....|:..:..:                     |.:.:.
Yeast   199 PFLSNDSFPLESL-NVWDLDTVDNGVMDYFHDHLQQDKEWDVMIGHMLGIDHVGHKYGPDHFTMR 262

  Fly   238 EATFN------------DSKTAYLYTSAHGLTYFGSHGGGSDEEREAPFLLWGAGVKHVTENITS 290
            |....            |..|..:....||:.:.|:|||.|.:|.|:...|:...........||
Yeast   263 EKQIQVDQFIDWILKSIDDDTLLVILGDHGMDHTGNHGGDSIDELESTLFLYSKKPDMWRLKETS 327

  Fly   291 DFVLNNGVGMQLHKLDQIQLAPLMSALIGLPPPVNNLAILPQGYMKVSREYARKSVHLNALQLLT 355
            ::.::| :|.....:.||.|...::.|:|.|.|.|||........:..||::         |.:.
Yeast   328 NYNIDN-LGHDYRSVRQIDLVSSLALLMGQPIPFNNLGWPIDEIARNDREWS---------QFVN 382

  Fly   356 QAKAIIRLHERGVFHKWLPKDKDLDLQQIAYYQNQMDHLLDMGWRSKALETSTLAIKVALKSLKF 420
            .|.:.::|::              |..|| ::.|  |.:|:.  .:|.: ::|.......|.:|.
Yeast   383 SAISQLQLYK--------------DTMQI-HHGN--DEILEP--LAKNI-SNTPPTSDPEKFVKL 427

  Fly   421 YHNYYHIPL-------------VVTTVLALLGWQFYQLVKLSQ-------NVMAPH--------- 456
            .|.|..:.|             .:.|.:.||......|:.:::       |.|.|.
Yeast   428 GHKYQKVFLQTCEELWAKFDYYSIATGITLLATSLVLLISITKLIPSIVVNQMVPEFVPGIIIMV 492

  Fly   457 -------------YMRRGYLT--WCTIFLASLGLL-------------------LGEMVFLQWA- 486
                         |.:..::.  |.|:...::|::                   |||.:...|:
Yeast   493 LVTNLCFHGIFYVYQQPSFVDQFWGTLLATAIGIIIGCYITIFDRYNFIWIAMRLGETLADYWSR 557

  Fly   487 ---PFMTVICLVV---PFGVW-CMTLAALPQNGG------WIFEPLKHLRWIVGPAAVMIASIYC 538
               .||.:..|:.   .|.:| ...:|.|....|      ::|.|.:.     ...|::.|:|
Yeast   558 IAVMFMIIHALLFTSNSFTIWEDRIVAFLLSTFGMLTLYEFVFLPKRQ-----STTALLTATI-- 615

  Fly   539 NCPLSLAYILCVGFYNRRG---WLHPS---PKFLAWLALVLLLGGFLWSQKGMQILMTTNYRVVL 597
                          ..:.|   .::||   ..:|.......||||:   ...:.|:.|
Yeast   616 --------------SEKEGTTSGVNPSTANSNYLPLTRFARLLGGY---HSAVLIIFT------- 656

  Fly   598 QAISMLVVIVR--------PCVLNENH-KWKVWVINGGILFV---------------------AA 632
             .::.::.|.|        |...|:|: .|  ||:  |:.|:                     ||
Yeast   657 -RLASMITICREEQGEYCIPTFNNQNNSSW--WVL--GLCFLMIFILPACITGYYNLTSSYQAAA 716

  Fly   633 ---IGIFLKEMGKPVPLYLFAANWAYLIYAFASVPCSSRTTPQSRLELIRFNLLTLHVLLSDSYV 694
               |.:|||.        :...|:.|  ::..|:..:|.......|..:.....||..:::.  .
Yeast   717 PIWINVFLKG--------ILGLNFVY--WSLTSLENNSAVIAIPFLRDVTIFKFTLARIIAG--F 769

  Fly   695 SLFAQGLIIEYQMG-----LEVHEKFKEADED---------------------VKILTSSKHLQ- 732
            ||.|..  :.:.||     |.:|....::.|.                     :.||..:|.|.
Yeast   770 SLIASN--VGWLMGPLCIKLNIHNTDVKSHEATILGYTNIYGSEFFLLVINVLISILLFNKPLAQ 832

  Fly   733 -----MCYRFAVSIL-------------------LYFYASLFGTGH--------WVGGFTYLANS 765
                 ||.:. :|||                   |..|...|.|||        |..||..   |
Yeast   833 LSYFLMCNQL-LSILEIIDLLKLKENIIGPIALGLLSYQHFFTTGHQATIPSVQWDIGFML---S 893

  Fly   766 ARLFLPDSSSGLVPLLVLIHLLIPSIVIMASVVALSSFGRQ----QIRTIFSSLM---------- 816
            .::..|     ...:.::::...|.|::..||..|:.:.:.    :.:|:...::
Yeast   894 EKVTFP-----FTQIAIILNTFGPHILVSLSVALLTLWSQPPDVLKPQTLLGRIVSNCGILLTYN 953

  Fly   817 -LICNAVVLFFVVFVPHNAYWPMAHPSVVHALLAQLTVILILACESI 862
             ::|.:..::...|..|...|.:..|..:.|.|:.:...|::...:|
Yeast   954 TILCLSSFIWVTHFRRHLMVWKIFCPRFIFASLSLIVTQLVVTFGTI 1000

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6790	NP_650087.2	GPI_EPT_1	83..331	CDD:293744	65/318 (20%)
		PigN	418..821	CDD:461508	100/592 (17%)
GPI13	NP_013069.1	GPI_EPT_3	77..367	CDD:293747	65/318 (20%)