DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6790 and NPP1

DIOPT Version :9

Sequence 1:	NP_650087.2	Gene:	CG6790 / 41388	FlyBaseID:	FBgn0037915	Length:	897	Species:	Drosophila melanogaster
Sequence 2:	NP_009955.2	Gene:	NPP1 / 850391	SGDID:	S000000621	Length:	742	Species:	Saccharomyces cerevisiae

Alignment Length:	242	Identity:	46/242 - (19%)
Similarity:	76/242 - (31%)	Gaps:	82/242 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 DIILRQGLVGISKTSVPTLTRSAEVALFAGFNPMPSILPTSNFDTIFNRTLAFDKGAFLRFSHLS 179
            |..|:|.:..:.:.::.:.|.    .:....:.|..|:..||  .|....|..:|
Yeast   389 DTFLKQLVESLQERNLTSFTN----LVIVSDHGMSDIVVPSN--VIIWEDLLDEK---------- 437

  Fly   180 DLRRRLTKRACLEKLWYANKLVMLVNLAEVGGASPLDIGFQMKLHNTQRNI-RDAYELI------ 237
             ||:.....|.||      ..:|.::|.:.|..:.:       .||.:.:| .|.|.:.
Yeast   438 -LRKDYVSHAYLE------GPMMAISLKDSGNINEV-------YHNLKTSIDEDKYTVYVNGNFP 488

  Fly   238 -EATFNDSKT------------AYLYTSAHGLTYFGSHGGGSDEEREAPFLLWGAGVKHVTENIT 289
             |..|||.|.            .|.......|... :.|...|:..:..|.:...|..
Yeast   489 KEWNFNDGKNHHMASIWIVPEPGYAVMKKEQLKKV-AKGDHKDKNEDNVFTIGSHGYD------- 545

  Fly   290 SDFVLNNGVGMQLHKLDQIQLAPLMSALIGLPPPVNNLAILPQGYMK 336
                 ||.:.|:             |..||:.|      ..||||::
Yeast   546 -----NNAIDMR-------------SVFIGMGP------YFPQGYIE 568

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6790	NP_650087.2	GPI_EPT_1	83..331	CDD:293744	42/235 (18%)
CG6790	NP_650087.2	PigN	418..821	CDD:282796
NPP1	NP_009955.2	Phosphodiest	170..545	CDD:396300	35/186 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900