DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6790 and AT3G01380

DIOPT Version :9

Sequence 1:	NP_650087.2	Gene:	CG6790 / 41388	FlyBaseID:	FBgn0037915	Length:	897	Species:	Drosophila melanogaster
Sequence 2:	NP_001326691.1	Gene:	AT3G01380 / 821231	AraportID:	AT3G01380	Length:	1001	Species:	Arabidopsis thaliana

Alignment Length:	1010	Identity:	221/1010 - (21%)
Similarity:	398/1010 - (39%)	Gaps:	233/1010 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 ELWKSKVVL---VHLLLLICIMRIFYQSGPLSQLEPQKTLLDMGVP-----PAADRLVVFLLEGL 97
            |.|  .|||   :|.:.::.|..|::::..:..::|        ||     |.|.|||:.:.:||
plant    43 ETW--LVVLGVALHAVYMLSIFDIYFKTPIVHGMDP--------VPPRFSEPPAKRLVLLISDGL 97

  Fly    98 RADTLFSDNCSG---AVYIRDIILRQGLVGISKTSVPTLTRSAEVALFAGFNPMPSILPTS---- 155
            |||..|..:..|   |.::|:||..||..|:|....||.:|...||:.|||...||.:...
plant    98 RADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARPPTESRPGHVAIIAGFYEDPSAVTKGWKAN 162

  Fly   156 --NFDTIFNR---TLAFDK-----------------------------GAFL---RFSHLSDLRR 183
              .||::||:   |.||..                             .:||   .|.....|..
plant   163 PVEFDSVFNQSRHTFAFGSPDIIPIFCSALPHSTWNSYPHEYEDFATDASFLDEWSFDQFEGLLN 227

  Fly   184 RLTKRACLEKLWYANKLVMLVNL--AEVGGAS--PLDIGFQMKLHNTQRNIRDAYELIEATFNDS 244
            |......|::|.:.:|||:.::|  .:..|.:  |....:...:....:.....|.|:|..:.|:
plant   228 RSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDN 292

  Fly   245 KTAYLYTSAHGLTYFGSHGGGSDEEREAPFLLWGAGV---KHVTENITSD----FVLNNGVGM-- 300
            :|:|::|:.||::..||||.|.....:.|.:.||||:   |..:.|..||    ||..:...|
plant   293 RTSYIFTADHGMSDKGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSHSDSVTTFVDKHAHDMPT 357

  Fly   301 -------QLHKLD--QIQLAPLMSALIGLPPPVNNLAILPQGYMKVSREYARKSVHLNALQLLTQ 356
                   ::.::|  |..:|||||.|:|||.|||::..||.||||::.....::|..|..|:|.|
plant   358 PYDWGLRRVERVDVNQADIAPLMSTLLGLPCPVNSVGNLPLGYMKLNEAEEVEAVVANTKQILNQ 422

  Fly   357 --AKAIIRLHERGVFHKWLPKDKDLDLQQIAYYQNQMDHLLDMGWRSKALETSTLAIKVALKSLK 419
              .|:.|:......|..:.|      |...::..:|:|.|:.......|::.:.....::|:.|.
plant   423 LLRKSYIKSSNSLFFKPFKP------LVHHSFSLSQIDELISAKSYEAAMKLAVDLRNLSLEGLH 481

  Fly   420 FYHNYYHIPLVVTTVLALLGWQFYQLVKLSQNVMAPHYMR-----------------------RG 461
            ::..|..:.|:....|...||..         |:|.|.::                       :.
plant   482 YFQTYDWLMLMTVITLGYTGWMI---------VLALHVLQCYSSLSGDLSKKEHLSVQKKDSGKV 537

  Fly   462 YLTWCTIFLASLGLL-------------LGEMVFLQWAPFMTVICLVVPFGVWCMTLAALPQNGG 513
            |::.| :.:|.|.:|             :|..||| |....:...|:  .|:|
plant   538 YISGC-LLMAILSVLNLVEHSPPLYHAYIGMTVFL-WTQIFSEYRLI--RGLW------------ 586

  Fly   514 WIFEPLKHLR----------WIVGPAAVMIASI----YCNCPLSLAYILCVG------FYNRRGW 558
                  |:||          ......||:|..:    :....|...:.|..|      .:....|
plant   587 ------KYLRERRADYFIKLLFAAAVAVVIVELLVHSFTERKLYTWFFLIAGVVASILLHFSIPW 645

  Fly   559 LHPSPKFL---AWLALVLLLGGFLWSQKGMQILMTTNYRVVLQAISMLVVIVRPCVLNENHK--- 617
            ....|.|:   .|...|..|         |...:..|..:|:.:.::::||.......:.|.
plant   646 RSGIPVFVCISCWFLSVFTL---------MPAEIPDNNNLVVTSGAIIIVISLAAKWLDTHAEGN 701

  Fly   618 --WK--------------VWVINGGILFVAAIGIFLKEMGKPVPLYLFAA----NWAYLIYAFAS 662
              |:              ::.|...::.|:::.:||....:.....|.::    ||   :.|.:|
plant   702 KFWQSITFHESRTQMCSMLYCIQIFLVGVSSVMVFLSTKHRTQNQELHSSHQFINW---LVAGSS 763

  Fly   663 --VPCSSRTTPQSRLELIRFNLLTLHVLLSDSYVSLFAQGLI------IEYQMGLEVHEKFKEA- 718
              :|..|.....|||..|........:|||..|.::|...|.      |.::.......|.||:
plant   764 MVLPLFSANGILSRLSSIFLGFAPPFLLLSIGYEAVFYSALAVVLMAWILFENASHHSSKVKESS 828

  Fly   719 ------DEDVKILTSSKHLQMC-YRFAVSILLYFYASLFGTGHWVGGFTYLANSARLFLPDSSSG 776
                  :|.:.|.:..::||:. .|..:..::.|..:.||||::....::..:|...|:...|..
plant   829 LSENNTEEHITIGSDERYLQLSDVRIPLVFMVLFNVAFFGTGNFASIASFEISSVYRFITIFSPF 893

  Fly   777 LVPLLVLIHLLIPSIVIMASVVALSSFGRQQIRTIFSSLMLICNAVVLFFVVFVPHNAYWPMAHP 841
            |:..|::..|.||.::::.:..|::...|......:..::|..:.:.:.|...|.:...|.....
plant   894 LMAALLIFKLFIPFMLVICAFSAITKLVRVPRLGCYFLVILFSDIMTIHFFFLVKNTGSWMEIGN 958

  Fly   842 SVVHALLAQLTVILILACESIVTIFFRRLNMNRCS 876
            |:.|..:....|:.:|...::..::.|.:.:...|
plant   959 SISHFGIVSAQVVFVLLLFALTNLYTRSIRIKPLS 993

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6790	NP_650087.2	GPI_EPT_1	83..331	CDD:293744	91/318 (29%)
CG6790	NP_650087.2	PigN	418..821	CDD:282796	90/500 (18%)
AT3G01380	NP_001326691.1	GPI_EPT_1	83..397	CDD:293744	90/313 (29%)
AT3G01380	NP_001326691.1	PigN	479..952	CDD:398585	92/515 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	119	1.000	Domainoid score	I1899
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55072
OrthoDB	1	1.010	-	-		D270107at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12250
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.890