Protein Alignment CG6790 and Pigo

DIOPT Version :10

• Sequence 1: NP_650087.2
• Gene: CG6790 / 41388
• FlyBaseID: FBgn0037915
• Length: 897
• Species: Drosophila melanogaster
• Sequence 2: NP_064419.3
• Gene: Pigo / 56703
• MGIID: 1861452
• Length: 1093
• Species: Mus musculus
• Alignment Length: 1207
• Identity: 232/1207 - (19%)
• Similarity: 377/1207 - (31%)
• Gaps: 480/1207 - (39%)

  Fly     2 KLALLQTFLWCFFSVVVNVSFVLYRRLTYRLVGKVQVLMEL------------------------ 42
            |:::|....|        |.|:.|..:.....|.:...:||
Mouse     3 KVSVLLFLAW--------VCFLFYAGIALFTSGFLLTRLELTNQSSCQELPGPGPLPWGSHGKPG 59

  Fly    43 --WK----SKVVLVHLLLLICIMRIFYQSGPLSQLEPQKTLLDMGVPPAADRLVVFLLE-GLRAD 100
              |.    |:||||    ||..:|..:       .:||::.:. |.||.:   |.||.: |....
Mouse    60 ACWMPSRFSRVVLV----LIDALRFDF-------AQPQRSHVP-GEPPVS---VPFLGKLGSLQR 109

  Fly   101 TLFSDNCSGAVYIRDIILRQGLVGISKTSVPTLTRSAEVALFAGFNPMPSILPT-SNF------- 157
            .|.|....|.:|            .|:...||.|.....||..|  .:|:.:.. |||
Mouse   110 ILESQPHHGRLY------------RSQVDPPTTTMQRLKALTTG--SLPTFIDAGSNFASHAIVE 160

  Fly   158 DTIFN-----------------RTL---AFDKGAFLRFSHLSDLRRRLTKRACLEKL-------- 194
            |.:..                 |.|   ||.:..|....::.||  .......||.|
Mouse   161 DNVIQQLNSAGRRVVFMGDDTWRDLFPGAFSQAFFFSSFNVRDL--HTVDNGILEHLYPTLDGGS 223

  Fly   195 WYANKLVMLVNLAEVGGA----SPLDIGFQMKLHNTQRNIRDAYELIEATFNDSKTAYLYTSAHG 255
            |.    |::.:...|...    .|.......||....:.|:.   |||...||  |..:....||
Mouse   224 WD----VLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQG---LIERLEND--TLLVVAGDHG 279

  Fly   256 LTYFGSHGGGSDEEREAPFLLWGAGVKHVTENITSDFVLNNGVGMQLHK-LDQIQLAPLMSALIG 319
            :|..|.|||.|:.|..|...|:            |...|...|..:..: :.|:.|.|.::.|:|
Mouse   280 MTMNGDHGGDSELEVSAALFLY------------SPTALFPSVPPEEPEVIPQVSLVPTLALLLG 332

  Fly   320 LPPPVNN----LAILPQGYMKVSREYARKSVHLNALQLLTQAKAIIRLHERGVFHKWLPKDKDLD 380
            ||.|..|    :|.|..|....|..::.....::||.:  .|:.:.|.     .|.:....:||.
Mouse   333 LPIPFGNTGEVMAELFSGGSDSSHPHSSALAQVSALHI--NAQQVSRF-----LHTYSAATQDLQ 390

  Fly   381 LQQI-----------AYYQNQMDHLLDMGWRSKALETSTLAIKVALKSLKFYHNYYHIPLVVTTV 434
            ::::           |.||:   .|.|......||.|.|...:..|:..:              .
Mouse   391 VKELHRLQTLFSKASARYQH---FLRDPQEAEAALSTLTAEFQQFLRGAR--------------A 438

  Fly   435 LALLGWQFYQLVKL-----------------SQNVMAPHYMRRGY--------LTWCTIFLASLG 474
            |.:..|..:.||::                 ||..:||.::.|..        ||| ||..|.:.
Mouse   439 LCIESWARFSLVRMAGGAALLAAACLLCLLASQLAVAPGFLFRPLLLIPVAWGLTW-TILYAGVS 502

  Fly   475 LLLGEMVFL------------------QW---------APFMTV-----ICLVVPFGVWCMTLAA 507
            :..|..:.|                  .|         ||.:.|     |.|::....:......
Mouse   503 VTTGSKIDLVVLGAVAAAGSLLPFLWKAWVSRGSKRPLAPLLPVPRPVLILLLIRLATFFSDSFV 567

  Fly   508 LPQN-------GGWIFEPLKHLRW---IVGPAAVMIASIYCNCPL-----SLAYILCVG-----F 552
            :.:.       |..:|..:..|.|   ::.|..:.::.:..:.|.     |.|:.|.:|     |
Mouse   568 VAEARATPFLLGSLVFFLVAQLHWEGQLLPPKPLTMSRLGSSAPTAPPRHSGAHALWLGIGLLLF 632

  Fly   553 YNRRGWLH------PSPKFLAWLA-LVLLLGG---FLWSQKGMQILMTTNYRVVLQAISMLVVIV 607
            ....|..|      |:.:...||: |..::||   .||            |...:.|:..|:|:|
Mouse   633 TRLAGLFHRCPEETPACRSSPWLSPLASMVGGRAKNLW------------YGACVGALVALLVVV 685

  Fly   608 R-------------PCVLNENHKWKV----------WVINGG----------------------I 627
            |             |.||..  :|.:          |.:..|                      :
Mouse   686 RLWLRRYGNLKSPEPPVLFV--RWGMPLMVLGTAAYWALASGAEEAPPRLRALVAGASAVLPRAV 748

  Fly   628 LFVAAIGIFLKEMGKPVPLYLFA----ANWAYLIYAFASVPCSSR----TTP----------QSR 674
            :.:||:|:.|. :.:||.:.:.|    :....::..|:..|.|..    ..|          |.|
Mouse   749 MGLAALGLVLL-LWRPVTVLVKAGAATSRTRTILTPFSGPPTSQADLDYVVPQIYRHMQEEFQGR 812

  Fly   675 LE----------------------------LIRFNLLTLHV-LLSDSYVSLFAQGLIIEYQMGLE 710
            ||                            |:.|.|:.||| .:|..::.||.|..::.:.:.
Mouse   813 LERTKAQGPITVAAYQLGSVYSAAMVTALLLLAFPLMLLHVERVSLVFLLLFLQSFLLLHLLA-- 875

  Fly   711 VHEKFKEADEDVKILTSSKHLQMCYRFAVSILL---YFYAS----LFGTGHWVGGFTYLANSARL 768
                     ....:.|......:....:..:||   .||::    :|...||        ::|.:
Mouse   876 ---------AGTPVATPGPFTVLWQAVSAWVLLATQTFYSTGHQPVFSAIHW--------HAAFV 923

  Fly   769 FLPD---SSSGLVPLLVLIHLLIPSIVIMASVVALSSFGRQQIRTIFSSLMLICNAVVLFFVVFV 830
            ..||   ||:.|           |::::.|:.              |:|.:|        |.|..
Mouse   924 GFPDGHGSSTWL-----------PALLVGANT--------------FASHLL--------FAVGC 955

  Fly   831 PHNAYWPMA----------------------------------------HPSVVHALLAQLTV-- 853
            |....||..                                        .|:..:|.|.||.:
Mouse   956 PLLLLWPFLCERQGPKRRQPLPGSESEARVRPEEEEELQEPLMEMRLRDAPNHFNAALLQLGLKY 1020

  Fly   854 --IL---ILACESIVTIFFRRLNMNRCSDWRQEADEF 885
              ||   ||||....:|..|.|.:     |:..|.:|
Mouse  1021 LFILGAQILACALAASILRRHLMV-----WKVFAPKF 1052

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6790	NP_650087.2	GPI_EPT_1	83..331	CDD:293744	69/293 (24%)
		PigN	418..821	CDD:461508	100/591 (17%)
Pigo	NP_064419.3	GPI_EPT_3	64..344	CDD:293747	79/331 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	971..991		0/19 (0%)