DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6790 and enpp5

DIOPT Version :9

Sequence 1:	NP_650087.2	Gene:	CG6790 / 41388	FlyBaseID:	FBgn0037915	Length:	897	Species:	Drosophila melanogaster
Sequence 2:	XP_005160520.3	Gene:	enpp5 / 563498	ZFINID:	ZDB-GENE-041014-10	Length:	512	Species:	Danio rerio

Alignment Length:	437	Identity:	75/437 - (17%)
Similarity:	115/437 - (26%)	Gaps:	210/437 - (48%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 LVHLLLLICIMRIFYQSGPLSQLEPQKTLLDMGVPPAADRLVVFLLEGLRADTLFSDNCSGAVYI 113
            ::....|.|::.:...||  ||.|.|..||          ||.|  :|.|.|           ||
Zfish    45 VIRSCFLSCLLALLQTSG--SQQEEQNQLL----------LVSF--DGFRWD-----------YI 84

  Fly   114 RDI-------ILRQG-LVGISKTSVPTLTRSAEVALFAGFN-PMPSILPTSNFDTIFNRTLAFD- 168
            ..:       ::.:| ||...:.:..|.|......|..|.: ....::....:|.|.||:.:.:
Zfish    85 NRVPTPNFHALMDEGVLVEKVENTYITKTYPNHYTLVTGLHAESHGVVANEMYDPIHNRSFSIEG 149

  Fly   169 ---------KGAFLRFSHLSDLRRRLTKRACLEKLWYANKLVMLVNLAEVGGASPLDIGFQMKLH 224
                     :.|                    |.||..|:.....:.|.:...|.:.||.....|
Zfish   150 PEVYDAWWWEEA--------------------EPLWVTNQKAGRKSGAAMWPGSDVAIGGTFPTH 194

  Fly   225 NTQRNIRDAYE--------------------------------------LIEATFND-------- 243
            ..:.|....:|                                      |::....|
Zfish   195 YLRYNASMLFETRVQKLIDWFSGPEAINFGVLYWEEPDESGHNLGPESPLMDVVLADIDEKLGFL 259

  Fly   244 ---SKTAYLY-------TSAHGLTYFGSHG----------------------------GGSDEE- 269
               .|:|.||       ||.||:|.. ||.                            .|..||
Zfish   260 REKLKSAGLYDKVNLIVTSDHGMTQL-SHDKIIELDTYVSRDLYTWIDKSPVVGILPKEGKLEEV 323

  Fly   270 -----------------------------REAPFLL-----WGAGVKHVTENITSDFVL-NNGVG 299
                                         |..|.::     |     .|.:|....|:| |:|..
Zfish   324 YGLLKNANPNMVVYKKEEIPDHYHYRHNARIMPLIIEVKEGW-----TVMQNRNGSFMLGNHGYN 383

  Fly   300 MQLHKLD--------------------QIQLAPLMSALIGLPPPVNN 326
            ..|..:.                    .:.|.|||.:::.|.|..||
Zfish   384 NSLPNMHPVFVARGPAFRRDYTKTSMRSVDLYPLMCSILALKPLPNN 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6790	NP_650087.2	GPI_EPT_1	83..331	CDD:293744	65/403 (16%)
CG6790	NP_650087.2	PigN	418..821	CDD:282796
enpp5	XP_005160520.3	Enpp	71..422	CDD:293742	63/399 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900