DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6790 and Enpp3

DIOPT Version :9

Sequence 1:	NP_650087.2	Gene:	CG6790 / 41388	FlyBaseID:	FBgn0037915	Length:	897	Species:	Drosophila melanogaster
Sequence 2:	NP_062243.2	Gene:	Enpp3 / 54410	RGDID:	708511	Length:	875	Species:	Rattus norvegicus

Alignment Length:	354	Identity:	70/354 - (19%)
Similarity:	115/354 - (32%)	Gaps:	124/354 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 TFLWCFFSVVVNVSFV-LYRRLT------YRLVGKVQVLMELWKSKVVLVHLLLLICIMRIFYQS 65
            ::.|....|.||.||. :||..:      .|:...:|.| :|.|::....:.:.:.......::|
  Rat   269 SYYWPGSDVAVNGSFPNIYRNYSNSVPYESRIATLLQWL-DLPKAERPSFYTIYVEEPDSAGHKS 332

  Fly    66 GPLSQLEPQKTLLDMGVPPA---ADRLVVFLLEGLRADTLFSDNCSGAVYIRDIILRQGLVGISK 127
            ||:|          .||..|   .|.....|:|||:...|  .||...:.:.|       .|:.:
  Rat   333 GPVS----------AGVIKALQLVDDAFGMLMEGLKQRNL--HNCVNIIVLAD-------HGMDQ 378

  Fly   128 TSVPTLTRSA----EVALFAGFNPMPSI----LPTSNFDTIFNRTLAFDKGAFLRFSHLS----- 179
            ||...:....    |:..:....|.|.|    :| .:|.|..:..:..|........|..
  Rat   379 TSCDRVEYMTDYFPEINFYMYQGPAPRIRTRNIP-QDFFTFNSEEIVRDLSCRKSDQHFKPYLTP 442

  Fly   180 DLRRRL--TKRACLEKL-------W--YANKLVMLVNLAEVGGASPLDIGFQMKLHNTQRNIRDA 233
            ||.:||  .|...::|:       |  |.||           |:|
  Rat   443 DLPKRLHYAKNVRIDKVHLMVDRQWLAYRNK-----------GSS-------------------- 476

  Fly   234 YELIEATFNDSKTAYLYTSAHGLTYFGSHGGGSD-EEREAPFLLWGAGVKHVTENITSDFVLNNG 297
                              :..|    |:||..:: :..||.||..|...|..|
  Rat   477 ------------------NCEG----GTHGYNNEFKSMEAIFLAHGPSFKEKT------------ 507

  Fly   298 VGMQLHKLDQIQLAPLMSALIGLPPPVNN 326
               .:...:.|::..|:..|:.:.|..||
  Rat   508 ---VIEPFENIEVYNLLCDLLHIQPAPNN 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6790	NP_650087.2	GPI_EPT_1	83..331	CDD:293744	51/272 (19%)
CG6790	NP_650087.2	PigN	418..821	CDD:282796
Enpp3	NP_062243.2	SO	51..94	CDD:197571
		Cell attachment site. /evidence=ECO:0000255	79..81
		SO	95..138	CDD:197571
		Phosphodiesterase	141..510		64/329 (19%)
		Phosphodiest	162..486	CDD:396300	57/290 (20%)
		Nuclease	605..875
		NUC	608..867	CDD:238043
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900