Protein Alignment CG6790 and ENPP2

DIOPT Version :10

• Sequence 1: NP_650087.2
• Gene: CG6790 / 41388
• FlyBaseID: FBgn0037915
• Length: 897
• Species: Drosophila melanogaster
• Sequence 2: XP_006716647.1
• Gene: ENPP2 / 5168
• HGNCID: 3357
• Length: 940
• Species: Homo sapiens
• Alignment Length: 255
• Identity: 52/255 - (20%)
• Similarity: 89/255 - (34%)
• Gaps: 77/255 - (30%)

  Fly    87 DRLVVFLLEGLRADTLFSDNCSGAVYIRDIILRQGL--VGISKTSVPT--LTRSAEVALFAGFNP 147
            |::|..|::||:  .|....|...:::.|    .|:  |...:|...:  ||...::.|..|
Human   385 DKIVGQLMDGLK--QLKLHRCVNVIFVGD----HGMEDVTCDRTEFLSNYLTNVDDITLVPG--- 440

  Fly   148 MPSILPTSNFDTIFNRTLAFDKGAFLR-------FSHLSD-LRRRLTKRACLEKLWYANKLVMLV 204
                 ......:.|:....:|..|.:.       ..|... |::.|.||     |.|||
Human   441 -----TLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQHLPKR-----LHYAN------ 489

  Fly   205 NLAEVGGASPLDIGFQMKLHNTQRNIRDAYELIEATFNDS-KTAYLYTSAHGLTYF-GSHG-GGS 266
                                  .|.|.|.:.|:|..::.: |...:|....|..:| |.|| ...
Human   490 ----------------------NRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNK 532

  Fly   267 DEEREAPFLLWGAGVKHVTENITSDFVLNNGVGMQLHKLDQIQLAPLMSALIGLPPPVNN 326
            ....:..|:.:|:..|:.|               ::...:.|:|..:|..|:||.|..||
Human   533 VNSMQTVFVGYGSTFKYKT---------------KVPPFENIELYNVMCDLLGLKPAPNN 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6790	NP_650087.2	GPI_EPT_1	83..331	CDD:293744	52/255 (20%)
		PigN	418..821	CDD:461508
ENPP2	XP_006716647.1	SO	55..98	CDD:197571
		SO	99..142	CDD:197571
		Phosphodiest	166..530	CDD:396300	39/191 (20%)
		AslA	<330..>413	CDD:442353	8/33 (24%)
		NUC	692..922	CDD:214683