DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6790 and PIG-G

DIOPT Version :9

Sequence 1:	NP_650087.2	Gene:	CG6790 / 41388	FlyBaseID:	FBgn0037915	Length:	897	Species:	Drosophila melanogaster
Sequence 2:	NP_610292.2	Gene:	PIG-G / 35685	FlyBaseID:	FBgn0033187	Length:	927	Species:	Drosophila melanogaster

Alignment Length:	971	Identity:	187/971 - (19%)
Similarity:	334/971 - (34%)	Gaps:	309/971 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 MELWKSKVV--LVHLLLLIC---IMRIFYQSGPLSQLEPQKT--------LLDMGV---PPAADR 88
            ||..||.:|  :..|...:|   :..|.:.....|..|.:.|        ||.|.:   |||.|.
  Fly     1 MEQHKSWLVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPPPAYDS 65

  Fly    89 LVVFLLEGLRADTLFSDNCSGAV-YIRDIILRQGLVGISKTSVP--------TLTRSAEVAL--- 141
            .|:.|::.||.|  |.|..|..| |.|.....:..|.|...::|        ||:...::||
  Fly    66 FVLLLVDALRDD--FPDATSMPVAYSRACEKLKLHVDIPTVTMPRLKSITTGTLSNFIDIALNVG 128

  Fly   142 ---------------------FAGFNPMPSILPTSNFDTIFNRTLAFDKGAFLRFSHLSDLRRRL 185
                                 |||.:....:.|:.     |.|.:......::...:..|.....
  Fly   129 HTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLFPSE-----FTRQVENHDSFYVNDFYEGDRNVTK 188

  Fly   186 TKRACLEKLWYANKLVMLVNLAEV----GGASPLDIGFQMKLHNTQRNIRDAYELIEATFNDSKT 246
            |....||:..::..::..:.|..:    |.|||          .....:::..|:::... |.|:
  Fly   189 TLETELERSDWSLLILHYLGLDHIGHVEGNASP----------RVPLKLKEMDEVVKKIL-DHKS 242

  Fly   247 ----AYLYTSAHGLTYFGSHGGGSDEEREAPFLLWGAGVKHVTENITSDFVLNN--GVGMQLHKL 305
                ..:.|..||:...|.|||.:..|...|..|:                .||  .......:.
  Fly   243 FPNVLLMLTGDHGMADGGGHGGNTPAETLVPLYLY----------------YNNCSKTPSASKRY 291

  Fly   306 DQIQLAPLMSALIGLPPPVNNL-AILPQGYMKVSREYARKSVHLNALQLLTQAKAIIRLHE---R 366
            :||.|||.:|.|:.:..|..:: .::|:....:|.|:...:...||..||.:|:.... ||   |
  Fly   292 NQIDLAPTLSVLLSVEIPTLSIGCLIPEMLQSLSLEHQLYAYFYNAHHLLNKARVKFG-HEIVHR 355

  Fly   367 GVFHKWLP-------------KDKDLDLQQIAYYQNQMDHLLDMGWRSKALETSTLAIKVALKSL 418
            ..::.|..             ::.|.......||||     ..:.:...|.|.|.|   ::...:
  Fly   356 SDYYTWYQNATLLHKKLLRPLREGDGGGASQVYYQN-----AKLNYMRVAREISDL---LSESLV 412

  Fly   419 KFYHNYYHIPLVVTT------VLALLGWQFYQLVKLSQNVMAPHYMRRGYLTWCTIFLASLGLLL 477
            ||.:.:..:.|.:||      |:::|.....:.::|.                        ||.:
  Fly   413 KFDYGFIAVGLALTTSTSLHIVISVLYLDLTEQLQLD------------------------GLKV 453

  Fly   478 GEMVFLQWAPFMTVICLVVPFGVWCMTLAALPQNGGWIFEPLKHLRWIVGPAAVMIASIYCNCPL 542
            |::                    |...:||:      :.....|...|:..::.:. ||....|:
  Fly   454 GQL--------------------WLSVIAAV------VLNYTSHALDIIMTSSTLY-SILLLVPI 491

  Fly   543 SLAYILCVG------------FYNRRGWLH---PSPKFLAWLALVLLLG--GFL------WSQKG 584
            |:|..|.:.            .|.||..:.   |.|....:....|.||  .|:      |...|
  Fly   492 SIAVYLTIDVAQALLKIALPPLYTRRLKISIPLPLPLLACYAIRTLTLGSSSFIEFEYNTWYYLG 556

  Fly   585 MQILMTTNYRVVLQAISMLVVIVRPCVLNENHKWKVW----VINGGILFVAAIGIFLKEMGKPVP 645
            ..:::.|.:|.:                    :|::.    .:||..|:..| ...|.:|.|.:.
  Fly   557 NTLILLTAFRTL--------------------RWRITKTNVELNGRHLYTIA-STCLWQMRKVLV 600

  Fly   646 LYLFAANWAYLIYAFASVPCSSRTTPQSRLELIRFNLLTLHVLLSDSYVSLFAQGLIIEYQMGLE 710
            :.:......|:                .||:.||..::...:||      |:|:         |.
  Fly   601 VLMLLTLMRYI----------------HRLQAIRSTVVIFSMLL------LWAR---------LH 634

  Fly   711 VHEKFKEADEDVKILTSSKHLQM--CYRFAVSILLYFYASLFGTGHWVGGFTYLANSARLFLPDS 773
            .|.:..::      |.|...|.|  |:|.....:|:|...           :::|  |:|
  Fly   635 RHSQLPQS------LASGAALFMVYCFRGLNGQVLFFDVP-----------SHMA--AKL----- 675

  Fly   774 SSGLVPLLVLIHLLIPSIVIMASVVAL---SSFGR--------QQIRTIFSSLMLIC------NA 821
               :||.||:....:..::::....||   .|||:        |.::|..:|.:|:.      :.
  Fly   676 ---MVPTLVIFWCCLALVLMLGYRAALPQAHSFGKVPPTGALLQLLQTNLTSSLLLAALLQRVHN 737

  Fly   822 VVLFFVVFVPHNAYWPMAHPSVVHALLAQLTVILILACESIVTIFFRRL------NMNRCS 876
            ::|..|:.|.....:.:.  .|......:.:|.|:...:.|:|||..|:      |.|..|
  Fly   738 ILLLPVLLVALQQTYKLC--DVYGTSARKFSVRLVHVYKIIMTIFLARMFFFYQGNSNSLS 796

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6790	NP_650087.2	GPI_EPT_1	83..331	CDD:293744	60/291 (21%)
CG6790	NP_650087.2	PigN	418..821	CDD:282796	78/454 (17%)
PIG-G	NP_610292.2	GPI_EPT_2	60..317	CDD:293748	60/290 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1524
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810