DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6790 and Enpp4

DIOPT Version :9

Sequence 1:	NP_650087.2	Gene:	CG6790 / 41388	FlyBaseID:	FBgn0037915	Length:	897	Species:	Drosophila melanogaster
Sequence 2:	XP_006244660.1	Gene:	Enpp4 / 301261	RGDID:	1308689	Length:	605	Species:	Rattus norvegicus

Alignment Length:	341	Identity:	56/341 - (16%)
Similarity:	107/341 - (31%)	Gaps:	145/341 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 YQSGPLSQLEPQKTLLDMGVPPAADRLVVFLLEGLRADTLF--------SDN----CS--GAVYI 113
            ::.||..:...::.|.::      |.|:..|::.|:|..|:        ||:    ||  ..:|:
  Rat   344 HKYGPEDKFNMRRVLKEV------DGLIGDLVQKLKALGLWESLNVIITSDHGMAQCSENRRIYL 402

  Fly   114 RDIILRQGLVGISKTSVPTLTRSAEVALFAGFNPMPSILPTSNFDTIFNRTLAFDKGAFLRFSHL 178
                  ...:..|..||..||            |:.:|||..|...::|           :..|.
  Rat   403 ------DTCINHSDYSVIDLT------------PVAAILPKINVTEVYN-----------KLKHC 438

  Fly   179 SDLRRRLTKRACLEKLWYAN----KLVMLVNLAEVGGASPLDIGFQMKLHNTQRNIRD-AYELIE 238
            :.......|.|...:.:|.:    :.::||          .|.|:.:.|:.:...:.| .|:
  Rat   439 NPHMTVYLKEAIPNRFYYQHSDRIQPILLV----------ADEGWTIALNTSSSKLGDHGYD--- 490

  Fly   239 ATFNDSKTAYLYTSAHGLTYFGSHGGGSDEEREAPFLLWGAGVKHVTENITSDFVLNNGVGMQLH 303
               |...:.:.:.:|||..:           |:                           |.:..
  Rat   491 ---NSLPSMHPFLAAHGPAF-----------RK---------------------------GYRQS 514

  Fly   304 KLDQIQLAPLMSALIGLPPPVNN-------------------------------------LAILP 331
            .::.:.:.|:|..::||.|..||                                     |.|..
  Rat   515 TINTVDIYPMMCYILGLKPHPNNGTFSHSKCLLVDQWCINLPEAIGIVVSALLALTVLTGLIIFM 579

  Fly   332 QGYMKVSREYARKSVH 347
            |.....||.::|..:|
  Rat   580 QNRASASRPFSRLQLH 595

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6790	NP_650087.2	GPI_EPT_1	83..331	CDD:293744	48/303 (16%)
CG6790	NP_650087.2	PigN	418..821	CDD:282796
Enpp4	XP_006244660.1	Enpp	177..530	CDD:293742	44/274 (16%)
Enpp4	XP_006244660.1	Phosphodiest	179..490	CDD:279931	35/190 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900