Protein Alignment CG6790 and PIG-O

DIOPT Version :10

• Sequence 1: NP_650087.2
• Gene: CG6790 / 41388
• FlyBaseID: FBgn0037915
• Length: 897
• Species: Drosophila melanogaster
• Sequence 2: XP_061507434.1
• Gene: PIG-O / 1276923
• VectorBaseID: AGAMI1_013429
• Length: 1147
• Species: Anopheles gambiae
• Alignment Length: 1018
• Identity: 201/1018 - (19%)
• Similarity: 314/1018 - (30%)
• Gaps: 386/1018 - (37%)

  Fly    83 PPAADRLVVFLLEGLRAD-TLFS-DNCSGAVY-----IRDIILR--------------------Q 120
            ||.| |:::.:::.||.| .|:: ||...|.|     |...:||                    |
Mosquito    86 PPKA-RVILLVIDALRYDFGLYNPDNPQPAPYENKLPIMTELLRKHPDHSRRLKFVADPPTTTMQ 149

  Fly   121 GLVGISKTSVPTLTRSAEVALFAGFNPMPSILPTSNFDTIFNRTLAFDK-GAFLRFSHLSDL-RR 183
            .|.||:..|:||.     :.:.:.|     ..|..|.|.:.::.:..:: ..||..|..::| ..
Mosquito   150 RLKGITTGSLPTF-----IDIGSNF-----ASPEINEDNLIDQVVRANRTSVFLGDSTWTELFPH 204

  Fly   184 RLTKRACLEKLWYANKLVMLVNLAEVGGASPLDIGFQMKLHNTQRNIRDAYELIEATF------- 241
            |.|:.       ||.....:.:|..|..|....:..:|        .|..::||.|.|
Mosquito   205 RFTRE-------YAYPSFNIYDLDTVDSAIERQLPREM--------ARGDWDLIVAHFLGVDHCG 254

  Fly   242 -----------------ND----------SKTAYLYTSAHGLTYFGSHGGGSDEEREAPFLLWGA 279
                             ||          ..|..|....||:|..|.|||.::.|.|:....:..
Mosquito   255 HRYGPVHDEMGRKLGEMNDVIRNITEQMADGTTLLVIGDHGMTQTGDHGGETENEVESLLFAYSK 319

  Fly   280 GVKHVTENITSDFVLNNGVGMQLHKLDQIQLAPLMSALIGLPPPVNNLA-----ILPQGYMKVSR 339
            |..          :|..........:.||.|.|.::.|:|:|.|.:||.     :||...:....
Mosquito   320 GSP----------LLPRAYDGHADTMQQIDLVPTLATLLGVPVPYSNLGQIMFQLLPDKRVDSFL 374

  Fly   340 EYARKSVHL--NALQ-------------------------------------LLTQA-------- 357
            .|....|||  ||.|                                     :|||.
Mosquito   375 RYQLALVHLWQNARQVQNYYQQYGEPRPIADATDPLEPDQEQELDDAENLFLMLTQRVNSVYTEA 439

  Fly   358 -----KAIIRLHERGVF----HKWLPKDKDLDLQQIAYYQNQMDH---LLDMGWRSKA-LETSTL 409
                 ...:|.:.||:.    ..|:..|..|           :.|   :..:|..|.| |...:.
Mosquito   440 AFQSFSGDLRHYLRGILDGYRRIWVKFDPQL-----------ISHGLLITFLGCFSMAILIVHSS 493

  Fly   410 AIKVALKSLKFYHNYYHIPLVVTTVLALLGWQFYQLVKLSQNVMAPHYMRRGYLTWCTIFLASLG 474
            |.::.....:..::.|...|||  ..|..|:..::|..||.   |.|    |.:.:.::   |..
Mosquito   494 AHQLVAMFTEGNNSSYAFLLVV--FAAQTGYACHELFGLSS---AQH----GVIMFGSV---SSV 546

  Fly   475 LLLGEMVFLQWA-------------------PFMTVICL---------------VVPFGVWCMTL 505
            |||..:....||                   .|:...|:               .|..|.:...|
Mosquito   547 LLLALLAIRHWASISENMASWKRSSNLLTRVSFVFTTCVFFANSFIVQEQKILSYVLMGFFLTAL 611

  Fly   506 AALPQNGGWIFEPLKHLRWIVGPAAVMIASIYCNCPLSLAYILCV----GFY------------- 553
            ..|.:.||..  .|..:||    |||..:::.....|:|..::.:    |::
Mosquito   612 YQLHRLGGRF--ALPRMRW----AAVRKSTLAKLVALTLFALVMIRLSGGYFRCREEQANCTDHL 670

  Fly   554 ------------NRRGWLHPSPKFLAWLALVLLLGGFLWSQKGMQILMTTNYRVVLQAISMLVVI 606
                        .||.........|..:||||.:.......|....|..|:..|:|......|.:
Mosquito   671 VKAPSTTSPTEGQRRRGTSADIGLLPCVALVLYIVCSRMYLKACGNLTGTSVNVLLARYGPTVAV 735

  Fly   607 VRPCVLNENHKWKV-------------WVINGGILFVAAIGIFLKEMGKPVPLYLF--------- 649
            |..|......|..|             ||:..  |.:..:|:.   :|.|:.||:.
Mosquito   736 VCTCAHFTVSKTGVQNGVPQLHVDALAWVVYA--LLLVQVGVL---VGSPLLLYVLPKRTDVLNV 795

  Fly   650 -----AANWAYLIY---------------AFASVP--CSSRTTPQSRLELIRFNLLTLHV-LLSD 691
                 .:|.|..||               :.|.:|  |...|. .|.:.:....|||:.: ||..
Mosquito   796 LYGGERSNLAPEIYRQLKENFRGRSGNDVSPADIPIVCGLGTV-YSSVFVAAGALLTITLALLLG 859

  Fly   692 SYVSL---------FAQGL---IIEYQMGLEVHEKFKEADEDVKILTSSKHLQMCYRFAVSILLY 744
            |:.::         .|.|:   |::|:.                   |...|..|.:.....||.
Mosquito   860 SHGTMGLIIVNCVAVAYGIIASILQYEQ-------------------SHTSLAGCIQPTFPTLLT 905

  Fly   745 FYA----SLFGTGH--------WVGGFTYLANSARLFLPDSSSGLVPLLVLIHLLIPSIVIMASV 797
            :..    ..|.|.|        |...|.     .|.:..|.|:.|...|||::
Mosquito   906 WVILQQYGFFATAHQPTLSQIDWNAAFV-----GRTYHFDGSNLLSGTLVLLN------------ 953

  Fly   798 VALSSFGRQQIRTIFSSLMLICNAVVLF-FVVFVPHNAY--WP 837
                         .||...|:.   ||| .:||||...|  ||
Mosquito   954 -------------TFSVTFLLS---VLFPLLVFVPFCVYTMWP 980

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6790	NP_650087.2	GPI_EPT_1	83..331	CDD:293744	68/315 (22%)
		PigN	418..821	CDD:461508	99/534 (19%)
PIG-O	XP_061507434.1	None