Protein Alignment Mrp4 and ABCC14

DIOPT Version :10

• Sequence 1: NP_650086.2
• Gene: Mrp4 / 41387
• FlyBaseID: FBgn0263316
• Length: 1316
• Species: Drosophila melanogaster
• Sequence 2: NP_191829.1
• Gene: ABCC14 / 825444
• AraportID: AT3G62700
• Length: 1539
• Species: Arabidopsis thaliana
• Alignment Length: 1344
• Identity: 441/1344 - (32%)
• Similarity: 718/1344 - (53%)
• Gaps: 135/1344 - (10%)

  Fly    17 SSPLSSLMFCFALPVLFKGRKKTLEQKDLYRALKEHKSDSLGDRLCAAWDEQVAKNETPRLGRAL 81
            :|.:|...:.:..|:|.||.|..|....:.....||:::.|.....:.|.:....:..| :...|
plant   253 ASFISKTFWLWMNPLLRKGYKSPLNLDQVPTLSPEHRAEKLATLFESKWPKPQENSRNP-VRTTL 316

  Fly    82 TKVFGFHLFITGVFLLAQEFLTKVTQPICLIGVMAYFAGNDPDRSKAQLWAAGLIAGSVFSVCIG 146
            .:.|...:..|.|..:.:..:..| .|:.:...:.:.:|.....|:.......|:......|...
plant   317 IRCFWKEIAFTAVLAIIRLSVIYV-GPVLIQSFVDFTSGKRSSPSQGYYLVLILLIAKFVEVLST 380

  Fly   147 HPYMLGLLHLGMKMRIALSSLIYRKALRLSRTALGDTTVGQVVNLLSNDVGRFDLVLINVHYLWI 211
            |.:......|||.:|..|.:.:|:|.|:|:.:|..:..|||:||.::.|..:...:::.:|.:|:
plant   381 HQFNFNSQKLGMLIRSTLITALYKKGLKLTGSARQNHGVGQIVNYMAVDAQQLSDMMLQLHAIWL 445

  Fly   212 APLELIAVTYLMYLEIG---ISSMFGVAIMLLFLPFQSYLG-KRTSVLRLRTALRTDERVRMMNE 272
            .||::.|...|:|..:|   ::::.|:..:.:|:    .|| ||.:..:....:..|.|::..||
plant   446 MPLQVAAAIVLLYNTLGPSVVTTVIGLTGIFVFI----LLGTKRNNRYQFSLMMNRDSRMKATNE 506

  Fly   273 IISGIQVIKMYAWEKPFGKVVEMTRFNEMLCIKQVNYIRGILISFAMFLSRIFTSSSLIA----- 332
            :::.::|||..|||..|.:  .:.:|.||    :..::...|.|.|..:..::::..||:
plant   507 MLNYMRVIKFQAWEDHFNE--RILKFREM----EFGWLSKFLYSIAGNIIVLWSTPVLISALTFT 565

  Fly   333 -FVLLGNILNAEKAFFVTAYYNILRRSVTMFFPQGISEFAELLVSVRRLEAFMHRPE--TKVRDK 394
             .|.||..|:|...|..|..:.||:..:.. |||.:...::.::|:.||:|:|...|  .:..::
plant   566 TAVFLGVKLDAGTVFTTTTIFKILQEPIRT-FPQSMISLSQAMISLGRLDAYMMSRELSEETVER 629

  Fly   395 SKVKNANQKAESPNGDSPKGNGIPENLIEFSQFQARWESHSLEPTLEDINLQLGRRKLVAVIGPV 459
            |:..:.|...|..:|             .||     |:....||.:|:||.::.:.:|.|::|.|
plant   630 SQGCDGNVAVEIKDG-------------SFS-----WDDEDDEPAIENINFEVKKGELAAIVGTV 676

  Fly   460 GAGKSSLIQAILGELPGESGTLRINGSYSYAAQEPWLFTGTVRQNILFGLDWDKHRYRTVVKKCA 524
            |:|||||:.::|||:...||.:|:.|:.:|.||..|:..|||:.||||||..::.:|..|:|.|.
plant   677 GSGKSSLLASVLGEMHKLSGKVRVCGTTAYVAQTSWIQNGTVQDNILFGLPMNRSKYNEVLKVCC 741

  Fly   525 LERDFELLPFGDKTIVGERGASLSGGQKARISLARAVYRRADIYLLDDPLSAVDTHVGRHLFDQC 589
            ||:|.:::.|||:|.:||||.:||||||.||.||||||:.:|:|||||..||||.|.|..:|.:|
plant   742 LEKDMQIMEFGDQTEIGERGINLSGGQKQRIQLARAVYQESDVYLLDDVFSAVDAHTGSDIFKKC 806

  Fly   590 MRGYLRSELVILVTHQLQFLEQADLIVIMDKGRISAMGTYSSMKRSGLDFAQLLTAPNKDAEDLD 654
            :||.|:.:.::|||||:.||...|.|::|..|.|...|.|..:..|||||.:|:.|.....|.::
plant   807 VRGALKGKTILLVTHQVDFLHNVDRILVMRDGMIVQSGKYDELVSSGLDFGELVAAHETSMELVE 871

  Fly   655 EIDGAGGDGLDLLNVPSLS---------------------RRGSKNSKPSTRNNSFTS------- 691
                ||.......|||..|                     |..|..|....|..|..|
plant   872 ----AGSASATAANVPMASPITQRSISIESPRQPKSPKVHRTTSMESPRVLRTTSMESPRLSELN 932

  Fly   692 ----LSSMAESMAQEAS-LQMQETRVEGKIGLGLYKEYLTSGSSWFMIFFMVFLCLATQILCSAA 751
                .|.:..::.::.| |..:|.|..|::...:||.|.|....|:.:..:||..:|.|....|:
plant   933 DESIKSFLGSNIPEDGSRLIKEEEREVGQVSFQVYKLYSTEAYGWWGMILVVFFSVAWQASLMAS 997

  Fly   752 DYFLSYWVDKNVDGQTDINTDPQDMYYFAALNVAVVVFTIVRTML--FY--KMAMRSSTQLHNAM 812
            ||:|:|    ....:.:::.|..   .|..:.|.:...:||...|  ||  .:.::::......:
plant   998 DYWLAY----ETSAKNEVSFDAT---VFIRVYVIIAAVSIVLVCLRAFYVTHLGLKTAQIFFKQI 1055

  Fly   813 YQGITRAAMYFFNTNPSGRILNRFSKDLGQLDEVLPSVMLDVVQLFLTLLGIIVVICITNPY--- 874
            ...:..|.|.||:|.||||||:|.|.|...:|..:|.::..|..::.|||.|.:|.|   .|
plant  1056 LNSLVHAPMSFFDTTPSGRILSRASTDQTNVDIFIPFMIGLVATMYTTLLSIFIVTC---QYAWP 1117

  Fly   875 --YLILTLALAIIFYYIREFYLKTSRDVKRLEAVARSPIYSHLSATITGLPTIRALGAQKELIAE 937
              :.|:.|....|:|  |.:||.:||::.||:::.::|:..|.|.:|.|:.||||.  :|:.:..
plant  1118 TVFFIIPLGWLNIWY--RGYYLASSRELTRLDSITKAPVIHHFSESIAGVMTIRAF--KKQPMFR 1178

  Fly   938 FDNLQ--------DLHSSGYYTFLATNRAFGYYLD-------CFCTLYIVIIILNYFINPPQSPG 987
            .:|::        |.|::|      :|...|:.|:       |...|::|::..|..     .|.
plant  1179 QENVKRVNANLRMDFHNNG------SNEWLGFRLELIGSWVLCISALFMVMLPSNII-----KPE 1232

  Fly   988 EVGLAITQAMGMTGMVQWAMRQSAELENTMTAVERVVEYDEIEPEGEFDSREGKKPSPSWPEKGE 1052
            .|||:::..:.:.|::.||:..|..:||.|.:|||:.::.:|..|.:::.:| .:|.|:||.||.
plant  1233 NVGLSLSYGLSLNGVLFWAIYLSCFIENKMVSVERIKQFTDIPAEAKWEIKE-SRPPPNWPYKGN 1296

  Fly  1053 IIAEDLCLRYFPDPQAKYVLKALNFRIRPCEKVGIVGRTGAGKSSLINALFRL-SYNEGIITIDE 1116
            |..||:.:||  .|....|||.|...|:..||:|:|||||:|||:||..|||| ..:.|.|.||.
plant  1297 IRLEDVKVRY--RPNTPLVLKGLTIDIKGGEKIGVVGRTGSGKSTLIQVLFRLVEPSGGKIIIDG 1359

  Fly  1117 RDTADMGLFDLRSKISIIPQEPVLFSGSMRYNLDPFEEYNDAKLWDALEEVKLKPLISELPNGLQ 1181
            .|...:||.||||:..|||||||||.|::|.|:||.|:|:|.::|.:||..:||.:::..|..|.
plant  1360 IDICTLGLHDLRSRFGIIPQEPVLFEGTVRSNIDPTEKYSDEEIWKSLERCQLKDVVASKPEKLD 1424

  Fly  1182 SKISEGGSNFSVGQRQLVCLARAILRENRVLVMDEATANVDPQTDALIQATIRSKFRDCTVLTIA 1246
            |.:::.|.|:|||||||:||.|.:|:.:|:|.:|||||:||.||||:||..||..|.|||:::||
plant  1425 SLVADNGENWSVGQRQLLCLGRVMLKRSRILFLDEATASVDSQTDAMIQKIIREDFSDCTIISIA 1489

  Fly  1247 HRLNTIMDSDRVLVMDAGHLVEFGSPYELLTSSESKIFHGMVME 1290
            ||:.|:||.|||||:|||...|:.||..||  ....:|..:|.|
plant  1490 HRIPTVMDCDRVLVIDAGKAKEYDSPVRLL--ERQSLFAALVQE 1531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mrp4	NP_650086.2	MRP_assoc_pro	13..1292	CDD:188098	441/1344 (33%)
ABCC14	NP_191829.1	MRP_assoc_pro	142..1534	CDD:188098	441/1344 (33%)