Protein Alignment Mrp4 and CG9270

DIOPT Version :10

• Sequence 1: NP_650086.2
• Gene: Mrp4 / 41387
• FlyBaseID: FBgn0263316
• Length: 1316
• Species: Drosophila melanogaster
• Sequence 2: NP_995741.2
• Gene: CG9270 / 35366
• FlyBaseID: FBgn0032908
• Length: 1292
• Species: Drosophila melanogaster
• Alignment Length: 1312
• Identity: 810/1312 - (61%)
• Similarity: 1014/1312 - (77%)
• Gaps: 35/1312 - (2%)

  Fly     4 MKADELPENPRERSSPLSSLMFCFALPVLFKGRKKTLEQKDLYRALKEHKSDSLGDRLCAAWDEQ 68
            |:|.:|..||||.:...|:||||||||:||||||||||..|||.||||||:::|||:..|.|..:
  Fly     1 MQAKKLQTNPRESAGIFSTLMFCFALPILFKGRKKTLEPTDLYNALKEHKAETLGDKFFATWQSE 65

  Fly    69 V-----AKNETPRLGRALTKVFGFHLFITGVFLLAQEFLTKVTQPICLIGVMAYFAGN-DPDRSK 127
            |     :..:.|.:.|.:.||||:.||::|:.:...|..|:.|.|:.|..::|.|..| :.|...
  Fly    66 VRSCGDSPKKEPSIIRVILKVFGWQLFLSGIVVGVLELGTRATLPLILGALIAEFTRNGNGDGLW 130

  Fly   128 AQLWAAGLIAGSVFSVCIGHPYMLGLLHLGMKMRIALSSLIYRKALRLSRTALGDTTVGQVVNLL 192
            ||::...||...:|||.:.||.|:||:||.||||:|:|:.|||||||||||||||||.||||||:
  Fly   131 AQIYGLTLILSILFSVLMFHPLMMGLMHLAMKMRVAVSTAIYRKALRLSRTALGDTTTGQVVNLI 195

  Fly   193 SNDVGRFDLVLINVHYLWIAPLELIAVTYLMYLEIGISSMFGVAIMLLFLPFQSYLGKRTSVLRL 257
            |||:||||..||:.|:||:.||||:..:|.:|.:||::|::|:.|:|||||.|::|.:.||.||.
  Fly   196 SNDLGRFDRALIHFHFLWLGPLELLISSYFLYQQIGVASLYGIVILLLFLPIQTFLSRLTSRLRH 260

  Fly   258 RTALRTDERVRMMNEIISGIQVIKMYAWEKPFGKVVEMTRFNEMLCIKQVNYIRGILISFAMFLS 322
            :||||||:||||||||||||||||||.||||||:::|..|.:||..|::||||||.|:||.:.||
  Fly   261 QTALRTDQRVRMMNEIISGIQVIKMYTWEKPFGRLIERLRRSEMSSIRKVNYIRGTLLSFEITLS 325

  Fly   323 RIFTSSSLIAFVLLGNILNAEKAFFVTAYYNILRRSVTMFFPQGISEFAELLVSVRRLEAFMHRP 387
            ||....||:.|||:|..|.||:||.|||:||||||:|..|||.|:|:|||::|::||::.||.|.
  Fly   326 RIAIFVSLLGFVLMGGELTAERAFSVTAFYNILRRTVCKFFPSGMSQFAEMMVTLRRIKGFMMRS 390

  Fly   388 ETKVRDKSKVKNANQKAESPNGDSPKGNGIPENLIEFSQFQARWESHSLEPTLEDINLQLGRRKL 452
            ||:.. ..|....|:..|.            |.|::...|||||....:||.||:||:.|...:|
  Fly   391 ETEAL-YLKGGQTNKLFEG------------EPLVKLQSFQARWNHDHVEPVLENINISLSPPQL 442

  Fly   453 VAVIGPVGAGKSSLIQAILGELPGESGTLRINGSYSYAAQEPWLFTGTVRQNILFGLDWDKHRYR 517
            ||||||||:||||||||||||||||||.|::.|..|||:||||||..:||.||||||..||||||
  Fly   443 VAVIGPVGSGKSSLIQAILGELPGESGKLKVQGDISYASQEPWLFNASVRDNILFGLPMDKHRYR 507

  Fly   518 TVVKKCALERDFELLPFGDKTIVGERGASLSGGQKARISLARAVYRRADIYLLDDPLSAVDTHVG 582
            .|::.|||||||||| .||:|.||||||||||||:|||||||||||:||.|||||||||||||||
  Fly   508 NVIRNCALERDFELL-HGDRTFVGERGASLSGGQRARISLARAVYRQADTYLLDDPLSAVDTHVG 571

  Fly   583 RHLFDQCMRGYLRSELVILVTHQLQFLEQADLIVIMDKGRISAMGTYSSMKRSGLDFAQLLTAPN 647
            ||||::||||:||.:|||||||||||||.||||||||||:|||:|||..|.:||.||.:||....
  Fly   572 RHLFEECMRGFLRDKLVILVTHQLQFLEHADLIVIMDKGKISAVGTYEEMLKSGQDFGKLLATEA 636

  Fly   648 KDAEDLD-EIDGAGGDGLDLLNVPSLSRRGSKNSKPSTRNNSFTSLSSMAESMAQEASLQMQETR 711
            ::..|.: |...|.||..:  :..:.||:.|:.|:.|.     ||:.|..||:........||:|
  Fly   637 QEMGDSNQEQVNAEGDSRN--DKSTYSRQSSRVSRVSV-----TSVDSSTESILDNERQPAQESR 694

  Fly   712 VEGKIGLGLYKEYLTSGSSWFMIFFMVFLCLATQILCSAADYFLSYWVDKNVDGQTDINTDPQDM 776
            .:||||||:|.:|.::||.|.|:..:.|.||.||||.|..|||||||| ||.|     ::...|:
  Fly   695 SQGKIGLGIYGKYFSAGSGWLMVILVAFFCLGTQILASGGDYFLSYWV-KNND-----SSSSTDI 753

  Fly   777 YYFAALNVAVVVFTIVRTMLFYKMAMRSSTQLHNAMYQGITRAAMYFFNTNPSGRILNRFSKDLG 841
            |.|:.:|.|:|:|.::||:||:.|||.|||||||.|:||::|.|:|||:.||||||||||:.|||
  Fly   754 YIFSGINAALVIFALLRTLLFFSMAMHSSTQLHNTMFQGVSRTALYFFHANPSGRILNRFAMDLG 818

  Fly   842 QLDEVLPSVMLDVVQLFLTLLGIIVVICITNPYYLILTLALAIIFYYIREFYLKTSRDVKRLEAV 906
            |:||:||:||||.:|:|||:.|||.|:|||||:|||.|:.:.:.|:::|.|||.||||:|||||:
  Fly   819 QVDEILPAVMLDCIQIFLTISGIIGVLCITNPWYLINTITMFLAFHFLRTFYLSTSRDLKRLEAI 883

  Fly   907 ARSPIYSHLSATITGLPTIRALGAQKELIAEFDNLQDLHSSGYYTFLATNRAFGYYLDCFCTLYI 971
            ||||:|||.|||:.||.||||:.||..|..|:||.||:|||||||||:||||||||||.||..|:
  Fly   884 ARSPMYSHFSATLNGLSTIRAMEAQDLLTKEYDNYQDIHSSGYYTFLSTNRAFGYYLDLFCVAYV 948

  Fly   972 VIIILNYFINPP-QSPGEVGLAITQAMGMTGMVQWAMRQSAELENTMTAVERVVEYDEIEPEGEF 1035
            :.:.|..:.||| .:||::||.|||||.|||.|||.|||||||||:||:||||:||..:|.||||
  Fly   949 ISVTLMSYFNPPVDNPGQIGLVITQAMSMTGTVQWGMRQSAELENSMTSVERVLEYRHLEAEGEF 1013

  Fly  1036 DSREGKKPSPSWPEKGEIIAEDLCLRYFPDPQAKYVLKALNFRIRPCEKVGIVGRTGAGKSSLIN 1100
            :|.:.|||..:||::|.|.||.|.|||.|||:|..|||:|||.|.|.||:|||||||||||||||
  Fly  1014 ESPDDKKPPMNWPQEGLISAEQLSLRYNPDPKADRVLKSLNFIIMPREKIGIVGRTGAGKSSLIN 1078

  Fly  1101 ALFRLSYNEGIITIDERDTADMGLFDLRSKISIIPQEPVLFSGSMRYNLDPFEEYNDAKLWDALE 1165
            ||||||||||.:.||..|...:||.||||||||||||||||||::|.||||||:|.|.|||:|||
  Fly  1079 ALFRLSYNEGSLVIDNTDILGIGLHDLRSKISIIPQEPVLFSGTLRCNLDPFEQYADEKLWEALE 1143

  Fly  1166 EVKLKPLISELPNGLQSKISEGGSNFSVGQRQLVCLARAILRENRVLVMDEATANVDPQTDALIQ 1230
            ||.||..:|||||||:|.::|||||:|||||||||||||||||||:|||||||||||||||||||
  Fly  1144 EVHLKDEVSELPNGLESVVAEGGSNYSVGQRQLVCLARAILRENRILVMDEATANVDPQTDALIQ 1208

  Fly  1231 ATIRSKFRDCTVLTIAHRLNTIMDSDRVLVMDAGHLVEFGSPYELLTSSESKIFHGMVMETGQNT 1295
            :|||.|||||||||||||||||:|||||:|:|||.|||||||:||||.|.||:|:|||::||:::
  Fly  1209 STIRRKFRDCTVLTIAHRLNTIIDSDRVMVLDAGTLVEFGSPFELLTQSWSKVFYGMVLQTGRSS 1273

  Fly  1296 FDSLLKVAEKAH 1307
            |:.|||:|.:||
  Fly  1274 FEHLLKLALEAH 1285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mrp4	NP_650086.2	MRP_assoc_pro	13..1292	CDD:188098	797/1286 (62%)
CG9270	NP_995741.2	PLN03130	10..1289	CDD:215595	806/1303 (62%)