DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr5 and Igsf9

DIOPT Version :9

Sequence 1:	NP_650080.3	Gene:	dpr5 / 41381	FlyBaseID:	FBgn0037908	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_001139272.1	Gene:	Igsf9 / 93842	MGIID:	2135283	Length:	1179	Species:	Mus musculus

Alignment Length:	281	Identity:	65/281 - (23%)
Similarity:	101/281 - (35%)	Gaps:	66/281 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 PDNYDAIDPVFDNTTDREVIAALGTTARLHCRVRHLGDRAVSW-IRQRDLHILTIGIMTYTNDQR 145
            |..:....|:.....:.|.:.       |.|..|......|:| .|.:||          ...|.
Mouse   135 PPQFQETPPLVLEVKELEAVT-------LRCVARGSPQPYVTWKFRGQDL----------GKGQG 182

  Fly   146 FLARHIDNSDEWVLKIVSVQQRDAGVYECQV-STEPKISLAYKLVVVTSKAQILANRELFIQSGS 209
            .:  .:.|...|:.:   |::..||.|.||. |:|..|:.|.:|:|:.....::......:.|..
Mouse   183 QV--QVQNGTLWIRR---VERGSAGDYTCQASSSEGSITHATQLLVLGPPVIVVPPSNSTVNSSQ 242

  Fly   210 DINLTCIAPQAPGPYTHMLWHKDTELVSDSARGGIRVESEQQMKTSNLVISRVQHTDSGNYTCSA 274
            |::|.|.|...|...|:. |.:|...|...:|...||   :.:...:|.:...|..|:|:|||..
Mouse   243 DVSLACRAEAYPANLTYS-WFQDGVNVFHISRLQSRV---RILVDGSLWLQATQPDDAGHYTCVP 303

  Fly   275 DNS----NSDSVFVHIIKSEQHAAMQHELGSRLLLPPLPLLLLAV----------LLVVL----- 320
            .|.    .|.|.::.::...|...|..|       .|||..:..|          ||.|.
Mouse   304 SNGFLHPPSASAYLTVLYPAQVTVMPPE-------TPLPTGMRGVIRCPVRANPPLLFVTWTKDG 361

  Fly   321 ------------LGPTSSLQI 329
                        |||..||.|
Mouse   362 QALQLDKFPGWSLGPEGSLII 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr5	NP_650080.3	V-set	95..191	CDD:284989	23/97 (24%)
		IG_like	98..179	CDD:214653	19/82 (23%)
		IG_like	206..278	CDD:214653	21/75 (28%)
		Ig	211..278	CDD:143165	19/70 (27%)
Igsf9	NP_001139272.1	IG_like	28..110	CDD:214653
		Ig	136..223	CDD:386229	24/108 (22%)
		Ig_3	227..305	CDD:372822	20/81 (25%)
		Ig	341..404	CDD:386229	10/42 (24%)
		Ig	436..500	CDD:319273
		FN3	508..599	CDD:238020
		FN3	625..715	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	767..807
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	819..842
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	942..974
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1016..1079
		PDZ-binding	1177..1179
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900