DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr5 and dscama

DIOPT Version :9

Sequence 1:	NP_650080.3	Gene:	dpr5 / 41381	FlyBaseID:	FBgn0037908	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	XP_021334866.1	Gene:	dscama / 568643	ZFINID:	ZDB-GENE-050310-7	Length:	2025	Species:	Danio rerio

Alignment Length:	268	Identity:	64/268 - (23%)
Similarity:	105/268 - (39%)	Gaps:	63/268 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 SNSRAPQIAHEMLVEYFMALLVIMGLTAPVDK--------QSRRSSQYFGHLAAAEELSNLIPDN 84
            |:||..|....:|:|          ...|.|.        .|..:::..|.|...|.|..::
Zfish   268 SDSRFRQSVTGLLIE----------RAQPSDTGSYVCEVWNSYGNAEVIGRLTVKEPLKAVV--- 319

  Fly    85 YDAIDPVFDNTTDREVIAALGTTARLHCRVRHLGDRAVSWIRQRD-----LHILTIGIMTYTNDQ 144
                       :.|:|..::|:...|.|.|....:..:||.|..|     .:|...||
Zfish   320 -----------SPRKVKGSVGSQVSLSCSVTGSDEFELSWYRNGDKINTGANIRMNGI------- 366

  Fly   145 RFLARHIDNSDEWVLKIVSVQQRDAGVYECQVSTEPKISLA--YKLVVVTSKAQIL-ANRELFIQ 206
                    |.:..|:.  .:.:.|.|||:| .|.:.|:|..  .::::.....:|| |..|..:.
Zfish   367 --------NKENLVMD--GMAKSDGGVYQC-FSRKAKMSAQDFVQVILEDGTPKILSAFSEKVVG 420

  Fly   207 SGSDINLTCIAPQAPGPYTHMLWHKDTELVSDSARGGI--RVESEQQMKTSNLVISRVQHTDSGN 269
            ....::|||.....|.|  .:.|..|.|:|:..:|..|  .:.:|..: .|.|.||.:|..|||.
Zfish   421 PNDFVSLTCHVKGTPQP--AITWTLDDEVVAKDSRHRIVHSITAEGNV-VSYLNISHIQVRDSGV 482

  Fly   270 YTCSADNS 277
            |.|:.:||
Zfish   483 YRCTCNNS 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr5	NP_650080.3	V-set	95..191	CDD:284989	23/102 (23%)
		IG_like	98..179	CDD:214653	21/85 (25%)
		IG_like	206..278	CDD:214653	24/74 (32%)
		Ig	211..278	CDD:143165	24/69 (35%)
dscama	XP_021334866.1	Ig	124..217	CDD:325142
		I-set	236..311	CDD:254352	11/52 (21%)
		IG_like	321..402	CDD:214653	23/98 (23%)
		I-set	408..502	CDD:333254	28/86 (33%)
		IGc2	524..579	CDD:197706
		Ig	614..679	CDD:319273
		Ig_DSCAM	708..787	CDD:143211
		Ig	805..898	CDD:325142
		FN3	894..988	CDD:238020
		FN3	995..1092	CDD:238020
		fn3	1100..1186	CDD:306538
		fn3	1199..1282	CDD:306538
		Ig	1312..1377	CDD:319273
		fn3	1405..1471	CDD:306538
		FN3	1492..1563	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810