DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr5 and paplna

DIOPT Version :9

Sequence 1:	NP_650080.3	Gene:	dpr5 / 41381	FlyBaseID:	FBgn0037908	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	XP_005169942.1	Gene:	paplna / 562930	ZFINID:	ZDB-GENE-070815-4	Length:	1187	Species:	Danio rerio

Alignment Length:	204	Identity:	52/204 - (25%)
Similarity:	83/204 - (40%)	Gaps:	41/204 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 VIAALGTTARLHCRVRHLGDRAVSWIRQRDLHILTIGIMTYTNDQRFLARHIDNSDEWVLKIVSV 164
            |.|..|.||:|.|.|     ..||.|....:|....|....:      .||..:|| ..|.|..:
Zfish   955 VEARAGQTAKLQCSV-----LPVSAIHAVTIHWSRAGQPLNS------LRHSQHSD-GTLVIKQL 1007

  Fly   165 QQRDAGVYECQVS-----TEPKISLAYKLVVVTSKAQILANRELFIQSGSDINLTCIAPQAPGPY 224
            ...|:|:|.|.|:     .|.::.|.....:..:||.|    ::.:..||...|.|:   ..|..
Zfish  1008 TADDSGLYTCTVTDAQKFEERQVQLRVLGDLRITKAPI----DVDVVQGSTAQLACV---VTGEN 1065

  Fly   225 THMLWHKDTELVSDSARGGIRVESE-QQMKTS---NLVISRVQHTDSGNYTCSADN---SNSDSV 282
            .::.|          :|.|:.|..: .::..|   .|:::.||..|.|.|||:|..   |.|.:.
Zfish  1066 VNVGW----------SRNGVPVRPDGHRVHVSADGTLILNNVQSVDEGTYTCNAYTGTLSVSAAA 1120

  Fly   283 FVHIIKSEQ 291
            .:.:.|:.|
Zfish  1121 EIRLAKTPQ 1129

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr5	NP_650080.3	V-set	95..191	CDD:284989	26/95 (27%)
		IG_like	98..179	CDD:214653	24/83 (29%)
		IG_like	206..278	CDD:214653	19/78 (24%)
		Ig	211..278	CDD:143165	17/73 (23%)
paplna	XP_005169942.1	TSP1	24..75	CDD:214559
		ADAM_spacer1	181..293	CDD:310520
		TSP1	303..356	CDD:214559
		TSP1	388..442	CDD:214559
		TSP1	449..498	CDD:214559
		TSP1	504..557	CDD:214559
		KU	720..771	CDD:238057
		Ig_3	839..906	CDD:316449
		IGc2	960..1022	CDD:197706	22/73 (30%)
		I-set	1039..1121	CDD:333254	24/98 (24%)
		PLAC	1142..1173	CDD:312271
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900