DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr5 and opcml

DIOPT Version :9

Sequence 1:	NP_650080.3	Gene:	dpr5 / 41381	FlyBaseID:	FBgn0037908	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_001005580.1	Gene:	opcml / 449538	ZFINID:	ZDB-GENE-040927-3	Length:	342	Species:	Danio rerio

Alignment Length:	370	Identity:	78/370 - (21%)
Similarity:	134/370 - (36%)	Gaps:	131/370 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 MGLTAPVDKQSRRSSQYFGHLAAAEELSNLIP--------DNYDAIDPVFDNTTDREVIAALGTT 107
            ||:|...:.|.:..      :..|..|..|:|        |:|     :.||.|.|:     |.:
Zfish     1 MGITGYFELQWKCL------VVVALRLLFLVPAGVPARSGDSY-----LKDNITVRQ-----GDS 49

  Fly   108 ARLHCRVRHLGDRAVSWIRQRDLHILTIGIMTYTNDQRFLARHIDNS--DEWVLKIVSVQQRDAG 170
            |.|.|.:.:...| |:|:.:..  ||..|...::.|.|.:   :.|:  :|:.:||::|...|.|
Zfish    50 AVLKCSMDNKVSR-VAWLNRTT--ILFTGNEKWSLDPRVV---LLNTAVNEYSIKILNVNLYDEG 108

  Fly   171 VYECQVSTEPKISLAYKLVVVTSKAQIL-ANRELFIQSGSDINLTCIAPQAPGPYTHMLW----H 230
            .|.|.:.|..|.......::|...|:|: .:.::.:..||:::|.|:|...|.|  .:||    .
Zfish   109 PYVCSILTNKKPESTKVHLIVQVPARIVNVSTDVSVNEGSNVSLMCLAIGRPEP--SILWKFRSS 171

  Fly   231 KDTELVSDS--------------------------------------------AR---------- 241
            |...:|::.                                            ||
Zfish   172 KGNRIVTEGEYVEMTGITKDMSGSYDCITSNDISPPDVRTVQVTVNYPPVISRARSTGTAVGQKG 236

  Fly   242 ---------------------------GGIRVESEQQMKTSNLVISRVQHTDSGNYTCSADNS-- 277
                                       .|:::|::.  |.|.|....|...|.|||||.|.|:
Zfish   237 VLWCEASAVPLADFQWFKGERRILNGFNGVKIENKG--KQSMLTFFNVSEEDYGNYTCVAINTLG 299

  Fly   278 -NSDSVFVHIIKSEQHAAMQHELGSRLLLPPLPLLLLAVLLVVLL 321
             .:.|:.::      .....|::.:..|.|...||||.:||.:.|
Zfish   300 ITNASIILY------GPGAIHDVNNAALSPTCSLLLLTLLLTLSL 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr5	NP_650080.3	V-set	95..191	CDD:284989	25/97 (26%)
		IG_like	98..179	CDD:214653	22/82 (27%)
		IG_like	206..278	CDD:214653	27/159 (17%)
		Ig	211..278	CDD:143165	25/154 (16%)
opcml	NP_001005580.1	Ig	41..129	CDD:299845	26/98 (27%)
		IG_like	41..129	CDD:214653	26/98 (27%)
		IG_like	139..216	CDD:214653	11/78 (14%)
		IGc2	146..202	CDD:197706	11/57 (19%)
		I-set	219..307	CDD:254352	17/89 (19%)
		ig	223..307	CDD:278476	17/85 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810