DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr5 and klg

DIOPT Version :9

Sequence 1:	NP_650080.3	Gene:	dpr5 / 41381	FlyBaseID:	FBgn0037908	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_524454.2	Gene:	klg / 42707	FlyBaseID:	FBgn0017590	Length:	545	Species:	Drosophila melanogaster

Alignment Length:	190	Identity:	55/190 - (28%)
Similarity:	87/190 - (45%)	Gaps:	30/190 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 AALGTTARLHCRVRHLGDRAVSWIRQRDLHILTIGIMTYTNDQRFLARHIDNSDEWVLKIVSVQQ 166
            |.:|.|..|.|:|.:||:..:.|  :|..::||...:..|.|:|  .|.||.   :.|:|..::.
  Fly   112 AVVGDTLVLPCQVENLGNFVLLW--RRGTNVLTASNIMVTRDER--VRLIDG---YNLEISDLEP 169

  Fly   167 RDAGVYECQVSTEPKISL----AYKLVVVTSKAQILANRELFIQSGSDINLTCIAPQAPGPYTHM 227
            :|||.|.||:|  .||:.    ..:::|..|...|..:.:|..:.|..|.|.|.....|.|  .:
  Fly   170 QDAGDYVCQIS--DKINRDQVHTVEILVPPSVRAIPTSGQLQARKGGPITLECKGSGNPVP--SI 230

  Fly   228 LWHKDTELVSDSAR---GGIRVESEQQMKTSNLVISRVQHTDSGNYTCSADNSNSDSVFV 284
            .|.|.:.....:||   |.|            |.:.:::...:|.|.|:|||...|.|.|
  Fly   231 YWTKKSGANKSTARIGDGPI------------LTLEKLERQQAGVYQCTADNGVGDPVTV 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr5	NP_650080.3	V-set	95..191	CDD:284989	29/92 (32%)
		IG_like	98..179	CDD:214653	27/76 (36%)
		IG_like	206..278	CDD:214653	19/74 (26%)
		Ig	211..278	CDD:143165	18/69 (26%)
klg	NP_524454.2	DUF1370	63..>124	CDD:284518	5/11 (45%)
		IG_like	109..195	CDD:214653	29/91 (32%)
		Ig	118..191	CDD:143165	26/81 (32%)
		IG_like	205..274	CDD:214653	20/82 (24%)
		IGc2	213..273	CDD:197706	19/73 (26%)
		IGc2	301..367	CDD:197706
		FN3	392..486	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810