DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr5 and Dscam3

DIOPT Version :9

Sequence 1:	NP_650080.3	Gene:	dpr5 / 41381	FlyBaseID:	FBgn0037908	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_996226.2	Gene:	Dscam3 / 42103	FlyBaseID:	FBgn0261046	Length:	2087	Species:	Drosophila melanogaster

Alignment Length:	241	Identity:	59/241 - (24%)
Similarity:	90/241 - (37%)	Gaps:	62/241 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 GTTARLHCRVRHLGDRAVSWIRQRDLHILTIGIMTYTNDQRFLARHIDNSDEWVLKIVSVQQRDA 169
            |.||..:|........|:.|:...........:.|..::.|||::.       .|.:.:|.:||.
  Fly   355 GGTANFNCTTTGSAIDAIDWLHNGKPLQANNALTTGRDNIRFLSKS-------SLLVQNVGRRDR 412

  Fly   170 GVYECQVSTEPKISLAYKLVVVTSKAQILANREL----------FIQS----GSDINLTCIAPQA 220
            |||:|.|..:            .:.||.:|..:|          ||:.    |..|:|.|.|..:
  Fly   413 GVYQCLVENQ------------RASAQAMAELKLGDTVPELIYTFIEQNVRPGPLISLKCSASGS 465

  Fly   221 PGPYTHMLWHKDTELVSD-SARGGIRVESEQQMK---TSNLVISRVQHTDSGNYTCSADNSNSDS 281
            |.|  ...|..|::.:.| |......:.....|.   .|:|.||.|:..|.|.|.|.|.||
  Fly   466 PPP--QFAWLLDSQPIMDVSLHHRFAIGQFVDMSGDVISHLNISHVRPDDGGLYKCVASNS---- 524

  Fly   282 VFVHIIKSEQHAAMQHELGSRLLLPPLPLLLLAVLLVVLLGPTSSL 327
                 :.|.||:|..:..|     ||         .|..:||..::
  Fly   525 -----MGSVQHSARLNVYG-----PP---------YVRAIGPIKAV 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr5	NP_650080.3	V-set	95..191	CDD:284989	19/85 (22%)
		IG_like	98..179	CDD:214653	19/73 (26%)
		IG_like	206..278	CDD:214653	23/79 (29%)
		Ig	211..278	CDD:143165	22/70 (31%)
Dscam3	NP_996226.2	IG	56..133	CDD:214652
		Ig	56..125	CDD:143165
		I-set	246..337	CDD:254352
		Ig	264..334	CDD:143165
		I-set	345..433	CDD:254352	22/96 (23%)
		Ig	358..431	CDD:143165	19/91 (21%)
		Ig	456..533	CDD:143165	26/87 (30%)
		IGc2	553..619	CDD:197706
		I-set	634..724	CDD:254352
		ig	645..712	CDD:278476
		IG_like	734..815	CDD:214653
		Ig	745..815	CDD:299845
		I-set	820..913	CDD:254352
		Ig	838..920	CDD:299845
		FN3	917..1033	CDD:238020
		FN3	1040..1142	CDD:238020
		fn3	1150..1237	CDD:278470
		FN3	1263..1345	CDD:238020
		Ig	1350..1436	CDD:299845
		IG_like	1358..1436	CDD:214653
		FN3	1441..1530	CDD:238020
		FN3	1542..1620	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810