DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr5 and kirrel1a

DIOPT Version :9

Sequence 1:	NP_650080.3	Gene:	dpr5 / 41381	FlyBaseID:	FBgn0037908	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_001349348.1	Gene:	kirrel1a / 405804	ZFINID:	ZDB-GENE-040426-2126	Length:	819	Species:	Danio rerio

Alignment Length:	353	Identity:	73/353 - (20%)
Similarity:	130/353 - (36%)	Gaps:	107/353 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 RATFTSTTATESSPLI-------GKVISNSRAPQIAHEMLVEYFMALLVIMGLTAPVDKQSRRSS 65
            |.||| ..||.:.|::       |.||..:|......:....:|         |.||      |.
Zfish   238 RVTFT-CQATANPPIMGYKWAKGGVVIQGARESVFVTKADHSFF---------TEPV------SC 286

  Fly    66 QYFGHLAAAEELSNLIPDNYD---AIDPVFDNTTDREVIAALGTTARLHCRVRHLGDRAVSWIRQ 127
            |.| :...:..:|.|:..::.   .::|       :.|...:.:...|:|:........::|.::
Zfish   287 QVF-NAVGSTNVSILVDVHFGPILVVEP-------KPVTVDVDSDVTLNCKWAGNPPLTLTWTKK 343

  Fly   128 RDLHILTIGIMTYTNDQRFLARHIDNSDEWVLKIVSVQQRDAGVYECQVSTEPKISLAYKLVVVT 192
            ....:|:                  |:::..||  ||.|.|||.|.|: :..|:|.:....|.:|
Zfish   344 GSSMVLS------------------NNNQLYLK--SVSQADAGQYVCK-AIVPRIGVGETEVTLT 387

  Fly   193 SKAQILANRELFIQS--GSDINLTCIAPQAPGP------YTHMLWHKDTELVSD---------SA 240
            .....:.:.|.|..:  |....:.|.....|.|      :...:|.|:...:|:         ||
Zfish   388 VNGPPIISSEPFQYAVRGERGEVKCYIASTPPPDKIVWAWKENVWEKEKGTLSERYTVEQSKPSA 452

  Fly   241 RGGIRVESEQQMKTSNLVISRVQHTD-SGNYTCSADNS-NSDSVFVHIIKSEQHAAMQHELGSRL 303
            :||..:        |.|.|:.:..:| ...|.|:|.|| .|.::.:.:.:.|
Zfish   453 QGGAVL--------STLTINNIMESDFQSTYNCTAWNSFGSGTMIISLEEME------------- 496

  Fly   304 LLPPLP-----------LLLLAVLLVVL 320
             :.|:.           ||||.:|.:||
Zfish   497 -IVPVGIIAGGTVGCSILLLLCLLALVL 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr5	NP_650080.3	V-set	95..191	CDD:284989	19/95 (20%)
		IG_like	98..179	CDD:214653	16/80 (20%)
		IG_like	206..278	CDD:214653	20/90 (22%)
		Ig	211..278	CDD:143165	19/83 (23%)
kirrel1a	NP_001349348.1	I-set	21..115	CDD:333254
		Ig2_KIRREL3-like	137..218	CDD:143236
		I-set	222..303	CDD:333254	20/81 (25%)
		Ig_3	307..372	CDD:316449	17/92 (18%)
		Ig5_KIRREL3	390..493	CDD:143306	23/110 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910