Protein Alignment dpr5 and LSAMP

DIOPT Version :10

• Sequence 1: NP_650080.3
• Gene: dpr5 / 41381
• FlyBaseID: FBgn0037908
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_001305844.1
• Gene: LSAMP / 4045
• HGNCID: 6705
• Length: 361
• Species: Homo sapiens
• Alignment Length: 340
• Identity: 72/340 - (21%)
• Similarity: 119/340 - (35%)
• Gaps: 131/340 - (38%)

  Fly    93 DNTTDREVIAALGTTARLHCRVRHLGDRAVSWIRQRDLHILTIGIMTYTNDQRFLARHID----N 153
            ||.|.|:     |.||.|.|.|.....: |:|:.:.       ||:...:|:..|...::    :
Human    39 DNITVRQ-----GDTAILRCVVEDKNSK-VAWLNRS-------GIIFAGHDKWSLDPRVELEKRH 90

  Fly   154 SDEWVLKIVSVQQRDAGVYECQVST--EPKISLAYKLVVVTSKAQILANRELFIQSGSDINLTCI 216
            |.|:.|:|..|...|.|.|.|.|.|  |||.|..|.:|.|..|...::: ::.:..||::.|.|:
Human    91 SLEYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLIVQVPPKISNISS-DVTVNEGSNVTLVCM 154

  Fly   217 APQAPGP-------------------YTHML---------------------------------- 228
            |...|.|                   |..:|
Human   155 ANGRPEPVITWRHLTPTGREFEGEEEYLEILGITREQSGKYECKAANEVSSADVKQVKVTVNYPP 219

  Fly   229 -------------------------------WHKDTELVSDSARGGIRVESEQQMKTSNLVISRV 262
                                           |::|...::.:  .|:.::|.:..  |:|.::.|
Human   220 TITESKSNEATTGRQASLKCEASAVPAPDFEWYRDDTRINSA--NGLEIKSTEGQ--SSLTVTNV 280

  Fly   263 QHTDSGNYTCSADN----SNSDSV-FVHIIKSEQHAAMQHELGSRL----------------LLP 306
            .....|||||.|.|    :|:..| |..::.:..|..  .|:|:.:                :..
Human   281 TEEHYGNYTCVAANKLGVTNASLVLFKRVLPTIPHPI--QEIGTTVHFKQKGPGSVRGINGSISL 343

  Fly   307 PLPLLLLAVLLVVLL 321
            .:||.|||..|:.||
Human   344 AVPLWLLAASLLCLL 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpr5	NP_650080.3	FR1	96..113	CDD:409355	6/16 (38%)
		IG_like	98..179	CDD:214653	24/86 (28%)
		Ig strand A'	100..102	CDD:409355	0/1 (0%)
		Ig strand B	106..114	CDD:409355	4/7 (57%)
		CDR1	114..120	CDD:409355	1/5 (20%)
		FR2	121..132	CDD:409355	2/10 (20%)
		Ig strand C	121..127	CDD:409355	2/5 (40%)
		Ig strand C'	130..133	CDD:409355	0/2 (0%)
		CDR2	133..146	CDD:409355	3/12 (25%)
		Ig strand D	146..151	CDD:409355	1/4 (25%)
		FR3	147..176	CDD:409355	10/32 (31%)
		Ig strand E	155..162	CDD:409355	2/6 (33%)
		Ig strand F	170..177	CDD:409355	3/6 (50%)
		IG_like	206..278	CDD:214653	23/159 (14%)
		Ig strand B	211..215	CDD:409353	1/3 (33%)
		Ig strand C	226..230	CDD:409353	1/68 (1%)
		Ig strand E	255..259	CDD:409353	2/3 (67%)
		Ig strand F	269..274	CDD:409353	4/4 (100%)
LSAMP	NP_001305844.1	Ig	38..128	CDD:472250	32/101 (32%)
		Ig strand B	49..53	CDD:409353	2/3 (67%)
		Ig strand C	61..65	CDD:409353	1/4 (25%)
		Ig strand E	94..98	CDD:409353	1/3 (33%)
		Ig strand F	108..113	CDD:409353	2/4 (50%)
		Ig strand G	121..124	CDD:409353	1/2 (50%)
		Ig_3	131..201	CDD:464046	10/70 (14%)
		Ig_3	218..294	CDD:464046	13/79 (16%)