DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr5 and CG7166

DIOPT Version :9

Sequence 1:	NP_650080.3	Gene:	dpr5 / 41381	FlyBaseID:	FBgn0037908	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_001262181.1	Gene:	CG7166 / 40401	FlyBaseID:	FBgn0037107	Length:	467	Species:	Drosophila melanogaster

Alignment Length:	225	Identity:	64/225 - (28%)
Similarity:	99/225 - (44%)	Gaps:	49/225 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 SNLIPDNYDAIDPVFDNTTDREVIA-------ALGTTARLHCRVRHLGDRAVSWIRQRDLHILTI 135
            |.::|:|    ||   .||..:.::       .:|.|..|.|:|::||...:.|  ::...:||.
  Fly    26 SFILPEN----DP---PTTAPKFLSRGHLYKVIVGETIELPCKVQNLGSFVLLW--RKGSSVLTA 81

  Fly   136 GIMTYTNDQRFLARHIDNSDEWVLKIVSVQQRDAGVYECQVSTE---PKISLAYKLVVVTSKAQI 197
            |.:..|.||||..     ..::.|:|..|:.:|||.|.||:..:   .::.....||..|.:| :
  Fly    82 GHLKITRDQRFKI-----VGDYNLQINGVKTQDAGDYICQLGDQENRDQVHTVEILVPPTLRA-L 140

  Fly   198 LANRELFIQSGSDINLTCIAPQAPGPYTHMLWHK------DTELVSDSARGGIRVESEQQMKTSN 256
            ..|.::..:.||.:.|.|.|...|.|  .:.|.|      .|.| |||               |.
  Fly   141 PHNGQVTARKGSTVTLECKASGNPVP--TIFWFKKDVFSGPTHL-SDS---------------ST 187

  Fly   257 LVISRVQHTDSGNYTCSADNSNSDSVFVHI 286
            |::..|....:|.|.|||||...|.|.:.|
  Fly   188 LILENVDRHHAGTYQCSADNGVKDRVSMDI 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr5	NP_650080.3	V-set	95..191	CDD:284989	29/105 (28%)
		IG_like	98..179	CDD:214653	25/87 (29%)
		IG_like	206..278	CDD:214653	24/77 (31%)
		Ig	211..278	CDD:143165	22/72 (31%)
CG7166	NP_001262181.1	IG_like	50..133	CDD:214653	25/89 (28%)
		Ig	56..116	CDD:143165	21/66 (32%)
		IG_like	144..221	CDD:214653	27/92 (29%)
		IGc2	151..209	CDD:197706	24/75 (32%)
		IG_like	232..313	CDD:214653
		Ig	242..311	CDD:143165
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	42	1.000	Domainoid score	I12424
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810