DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr5 and IGLON5

DIOPT Version :9

Sequence 1:NP_650080.3 Gene:dpr5 / 41381 FlyBaseID:FBgn0037908 Length:336 Species:Drosophila melanogaster
Sequence 2:NP_001094842.1 Gene:IGLON5 / 402665 HGNCID:34550 Length:336 Species:Homo sapiens


Alignment Length:317 Identity:68/317 - (21%)
Similarity:108/317 - (34%) Gaps:117/317 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    92 FDNTTDREVIAALGTTARLHCRV-RHLGDRAVSWIRQRDLHILTIGIMTYTNDQRFLARHIDNSD 155
            |::..|...:.. |..|.|.|.: .|:  ..|:|:.:.  :||..|...:|:|.| :...|:..:
Human    35 FNSPADNYTVCE-GDNATLSCFIDEHV--TRVAWLNRS--NILYAGNDRWTSDPR-VRLLINTPE 93

  Fly   156 EWVLKIVSVQQRDAGVYECQVST--EPKISLAYKLVVVTSKAQILANRELFIQSGSDINLTCIAP 218
            |:.:.|..|...|.|:|.|...|  :|..:..|.:|.|.::. :..:..:.:..|.::||.|:|.
Human    94 EFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARI-VNISSPVTVNEGGNVNLLCLAV 157

  Fly   219 QAPGP---------------------------------YTH------------------------ 226
            ..|.|                                 .||                        
Human   158 GRPEPTVTWRQLRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITD 222

  Fly   227 -------------------------MLWHKDTELVSDSARGGIRVESEQQMKTSNLVISRVQHTD 266
                                     ..|:||..|:|.....|::|::|:  ..|.|:.:.|....
Human   223 VTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTER--TRSMLLFANVSARH 285

  Fly   267 SGNYTCSADNSNSDSVFVHIIKSEQHAAMQHELGSRLLLP-------PLPLLLLAVL 316
            .|||||.|.|....|          .|:|      |||.|       |.|..|||:|
Human   286 YGNYTCRAANRLGAS----------SASM------RLLRPGSLENSAPRPPGLLALL 326

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr5NP_650080.3 V-set 95..191 CDD:284989 26/98 (27%)
IG_like 98..179 CDD:214653 22/83 (27%)
IG_like 206..278 CDD:214653 27/153 (18%)
Ig 211..278 CDD:143165 26/148 (18%)
IGLON5NP_001094842.1 Ig 41..129 CDD:416386 24/93 (26%)
Ig strand A' 41..46 CDD:409353 0/4 (0%)
Ig strand B 48..56 CDD:409353 3/7 (43%)
CDR1 56..60 CDD:409353 0/3 (0%)
FR2 61..68 CDD:409353 2/6 (33%)
Ig strand C 61..67 CDD:409353 2/5 (40%)
CDR2 69..79 CDD:409353 3/11 (27%)
Ig strand C' 71..74 CDD:409353 2/2 (100%)
Ig strand C' 76..79 CDD:409353 0/2 (0%)
FR3 80..115 CDD:409353 11/35 (31%)
Ig strand D 84..91 CDD:409353 2/7 (29%)
Ig strand E 94..100 CDD:409353 1/5 (20%)
Ig strand F 107..115 CDD:409353 3/7 (43%)
CDR3 116..120 CDD:409353 1/3 (33%)
Ig strand G 120..129 CDD:409353 2/8 (25%)
FR4 122..129 CDD:409353 1/6 (17%)
Ig_3 134..199 CDD:404760 8/65 (12%)
Ig strand B 148..157 CDD:409353 3/8 (38%)
Ig strand C 162..170 CDD:409353 1/7 (14%)
Ig strand F 191..199 CDD:409353 1/7 (14%)
Ig strand G 202..212 CDD:409353 0/9 (0%)
Ig_3 217..295 CDD:404760 17/79 (22%)
putative Ig strand A 218..224 CDD:409353 0/5 (0%)
Ig strand B 234..238 CDD:409353 0/3 (0%)
Ig strand C 247..251 CDD:409353 0/3 (0%)
Ig strand E 274..278 CDD:409353 2/3 (67%)
Ig strand F 288..293 CDD:409353 4/4 (100%)
Ig strand G 301..304 CDD:409353 1/2 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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