DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr5 and DIP-beta

DIOPT Version :9

Sequence 1:	NP_650080.3	Gene:	dpr5 / 41381	FlyBaseID:	FBgn0037908	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster

Alignment Length:	300	Identity:	74/300 - (24%)
Similarity:	120/300 - (40%)	Gaps:	71/300 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 TESSPLIGKVISNSRAPQIAHEM---------------------LVEYFMALLVIMGLTAPVDKQ 60
            |:.||.:.:|..:.:..|:  |:                     .:.:.:.||:::|....:...
  Fly    25 TKFSPKLSQVAKHRKLAQL--EIASGSGLVGLGTGTGTGSGCGPAIRWQLLLLLLLGNCIDLTVS 87

  Fly    61 SRRSSQYFGHLAAAEELSNLIPDNYDAIDPVFDNTTDREVIAALGTTARLHCRVRHLGDRAVS-- 123
            ::.||      ..|.|...:||         .:|.|     .|.|..|...|.|.:||...||
  Fly    88 NKISS------VGAFEPDFVIP---------LENVT-----IAQGRDATFTCVVNNLGGHRVSGD 132

  Fly   124 ---------WIRQRDLHILTIGIMTYTNDQRFLARHIDNSDEWVLKIVSVQQRDAGVYECQVSTE 179
                     ||:.....||.|.....||:.|...:|.| .:.|.|.|..|:..|||.|.|||:|:
  Fly   133 GSSAPAKVAWIKADAKAILAIHEHVITNNDRLSVQHND-YNTWTLNIRGVKMEDAGKYMCQVNTD 196

  Fly   180 P-KISLAYKLVVVTSKAQILANRE----LFIQSGSDINLTCIAPQAPGPYTHMLWHKD--TELVS 237
            | |:..|...||:...   :.|.|    :.:..|....|.|.|...|.|  .:.|.::  .|::
  Fly   197 PMKMQTATLEVVIPPD---IINEETSGDMMVPEGGSAKLVCRARGHPKP--KITWRREDGREII- 255

  Fly   238 DSARGGIRVESE-QQMKTSNLVISRVQHTDSGNYTCSADN 276
              ||.|...::: |.::...|.:|::..::.|.|.|.|.|
  Fly   256 --ARNGSHQKTKAQSVEGEMLTLSKITRSEMGAYMCIASN 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr5	NP_650080.3	V-set	95..191	CDD:284989	36/107 (34%)
		IG_like	98..179	CDD:214653	30/91 (33%)
		IG_like	206..278	CDD:214653	18/73 (25%)
		Ig	211..278	CDD:143165	17/68 (25%)
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	39/125 (31%)
		ig	102..195	CDD:278476	34/107 (32%)
		IG_like	219..307	CDD:214653	18/79 (23%)
		Ig	221..307	CDD:299845	18/77 (23%)
		Ig	311..404	CDD:299845
		IG_like	327..405	CDD:214653
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810